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A modified model based on kinetic rate theory is presented to simulate the dose dependence of defects nucleation and growth in reduced-activation ferritic/martensitic (RAFM) steel under helium ion irradiation by considering the motion of dislocation loops. The modeling results are compared with the transmission electron microscopy (TEM) experiments. The TEM analysis shows that the mean size of dislocation loops increases with the increasing atomic displacement damage dose, while the density of the observed loops exhibits minor change. To investigate the evolution of dislocation loops, we compare two cases incorporating mobile and immobile interstitial clusters in our modified model, respectively. The calculated results reveal a good agreement with experiments in the case of considering mobile interstitial clusters. It is included the motion of interstitial clusters plays an important role in the evolution of dislocation loops in RAFM steel. [ABSTRACT FROM AUTHOR]