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Abstract: Using an Atmospheric Global Circulation Model, we assess the relevance of selected atmospheric mechanisms for climate evolution of Saharan and sub-Saharan regions since the Miocene. First, we test the influence of the East-African Rift System uplift on atmospheric dynamics. Although the uplift played an important role in triggering East-African rainfall, no significant impact over central and western Africa has been detected. We also analyse the feedbacks of a giant lake on the climate of Chad basin. First results infer a negative feedback of the giant lake on the water balance, as convection is weakened by the cold water surface and as water evaporated from the lake does not feed the basin hydrological cycle. Lastly, we suggest that colder than present sea surface temperatures over the Gulf of Guinea reinforce the West-African monsoon, by enhancing the moisture advection engine via stronger thermal contrast between the ocean and the continent. [Copyright &y& Elsevier]