1. Personal characteristics of older primary care patients who provide a buccal swab for apolipoprotein E testing and banking of genetic material: the spectrum study
- Author
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Peter V. Rabins, Joseph J. Gallo, Jon F. Merz, Hillary R. Bogner, Joseph B. Straton, Peter F. Cronholm, and Marsha N. Wittink
- Subjects
Gerontology ,Apolipoprotein E ,Male ,medicine.medical_specialty ,Genotype ,Buccal swab ,Primary care ,Article ,Apolipoproteins E ,stomatognathic system ,Internal medicine ,medicine ,Humans ,Genetics (clinical) ,Genetic testing ,Aged ,Aged, 80 and over ,Chi-Square Distribution ,medicine.diagnostic_test ,Primary Health Care ,business.industry ,Racial Groups ,Public Health, Environmental and Occupational Health ,Age Factors ,Logistic Models ,lipids (amino acids, peptides, and proteins) ,Female ,Patient Participation ,business - Abstract
Objective: To determine the personal characteristics and reasons associated with providing a buccal swab for apolipoprotein E (APOE) genetic testing in a primary care study. Methods: The study sample consisted of 342 adults aged 65 years and older recruited from primary care settings. Results: In all, 88% of patients agreed to provide a DNA sample for APOE genotyping and 78% of persons providing a sample agreed to banking of the DNA. Persons aged 80 years and older and African-Americans were less likely to participate in APOE genotyping. Concern about confidentiality was the most common reason for not wanting to provide a DNA sample or to have DNA banked. Conclusion: We found stronger relationships between sociodemographic variables of age and ethnicity with participation in genetic testing than we did between level of educational attainment, gender, function, cognition, and affect.
- Published
- 2005