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The first probabilistic definition of the geometric mean of a non negative random variable under certain assumptions was given in Feng et al. (2013). In this paper, we generalize the definition to a larger class of random variables. We also show the basic properties of the geometric mean and point out its discontinuity and instability. Some convergence properties are studied as well, for which we emphasize its link to the positive moments of the random variable. A discussion of potential applications of the new definition in biomedical research and open questions to complete the theory of geometric mean is highlighted. [ABSTRACT FROM PUBLISHER]

Andersen's plot, a graphical method for testing the proportionality assumption in the Cox Regression Model (Cox, 1972), first proposed by Kay (1977) and popularized by Andersen (1982), has been used widely in biomedical research to check the validity of applying this popular regression model in survival analysis. Our theoretical derivation and examples show that the theoretical basis of this method is flawed. The graphical method should not be used in testing the proportionality. Instead, formal analytical methods based on residuals such as Cox–Snell residual and martingale residual should be used in practice. [ABSTRACT FROM PUBLISHER]

In this article, we compare the zero-inflated Poisson (ZIP) and negative binomial (NB) distributions based on three most important criteria: the probability of zero, the mean value, and the variance. Our results show that with same mean value and variance, the ZIP distribution always has a larger probability of zeros; with same mean value and probability of zeros, the NB distribution always has a larger variance; and with same variance and probability of zeros, the ZIP distribution always has a larger mean value. We also study the properties of Vuong test in model selection in three cases by simulations. [ABSTRACT FROM PUBLISHER]