1. Highly selective differential pulse voltammetric determination of phenazopyridine using MgCr2O4 nanoparticles decorated MWCNTs-modified glassy carbon electrode.
- Author
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Ensafi AA, Arashpour B, Rezaei B, and Allafchian AR
- Subjects
- Calibration, Dielectric Spectroscopy, Electricity, Electrodes, Humans, Hydrogen-Ion Concentration, Limit of Detection, Nanoparticles ultrastructure, Nanotubes, Carbon ultrastructure, Solutions, Chromium Compounds chemistry, Electrochemical Techniques methods, Glass chemistry, Magnesium Compounds chemistry, Nanoparticles chemistry, Nanotubes, Carbon chemistry, Oxides chemistry, Phenazopyridine blood, Phenazopyridine urine
- Abstract
A selective modified glassy carbon electrode based on multiwall carbon nanotubes decorated with MgCr2O4 nanoparticles was fabricated and used for the determination of phenazopyridine using differential pulse voltammetry. The electrochemical response of the modified electrode toward phenazopyridine was characterized by different electrochemical methods including differential pulse voltammetry (DPV), cyclic voltammetry (CV), and impedance spectroscopy. The prepared electrode showed an efficient synergic effect on the oxidation of phenazopyridine at pH 6.0. The oxidation peak current was proportional to the concentration of phenazopyridine from 0.05 to 7.5 μmol L(-1). The detection limit was 0.025 μmol L(-1). The applicability of the method was confirmed with satisfactory results obtained through the assay of phenazopyridine in human plasma, urine samples, and pharmaceuticals., (Copyright © 2013 Elsevier B.V. All rights reserved.)
- Published
- 2013
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