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Despite the rapid improvement in dental health over the last few decades, a significant portion of our population continue seek dental care every year. Estimates show that 13% of adults seek dental care for dental infection or fatigue within four years. The Social and individual burden of this disease can be reduced by its early detection. However, the symptoms of teeth infection in the early stages are not clear, hence, it would be relatively difficult to predict teeth infections based solely on human skills and experience. Big Data (BD) technologies have a great potential in transforming dental care, as they have revolutionized other industries. In addition to reducing cost, they could save millions of lives and improve patient outcomes. This paper proposes a novel integrated prediction model that extracts hidden knowledge from radiographic datasets containing a large volume of dental X-ray images and utilizes this knowledge to predict dental infections. Initially, preprocessing techniques using morphological skeleton and mean approach is applied to eliminate noise and enhance the images. Next, Multi Scale Segmented Region (MSR) approach, Watershed Approach (WA), Sobel edge Detection (SD), Histogram based Segmentation (HS), Trainable Segmentation (TS), Dual Clustering (DC), and Fuzzy C-Means clustering (FCM) are examined for image segmentation and feature extraction. Among these methods, MSR was selected for feature extraction since it outperformed other methods in terms of accuracy, specificity, precision, recall and F1-score. Then, a set of neural network classifiers are trained to identify patterns in the extracted optimized features and predict dental infections. For this purpose, we have examined Bacterial Optimized Recurrent Neural Networks (BORNN), Deep Learning Neural Networks (DANN), Genetic Optimized Neural Networks (GONN) and Adaptive Neural Networks Algorithm (ADNN). BORNN have shown maximum accuracy and Roc value (98.1% and 0.92 respectively), and minimum error values (MSE = 0.189, MAE = 0.143). The output of the proposed integrated prediction model is fed into a dental robot who proceeds with the treatment process with high accuracy and minimum delay. The proposed prediction model was implemented using a big data analytics tool called Apache SAMOA and experimental results showed its correctness and effectiveness. [ABSTRACT FROM AUTHOR]