1. Anatomic pathology of hepatocellular carcinoma: histopathology using classic and new diagnostic tools.
- Author
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Pittman ME and Brunt EM
- Subjects
- Biopsy, Diagnosis, Differential, Eosine Yellowish-(YS), Hematoxylin, Humans, Immunohistochemistry, Liver Neoplasms secondary, Carcinoma, Hepatocellular pathology, Coloring Agents, Liver pathology, Liver Neoplasms pathology, Precancerous Conditions pathology
- Abstract
Hepatocellular carcinoma can be diagnosed on a needle biopsy of the liver; however, uncertainty may arise because of the inherent complexity of liver histology. This article aims to provide practicing pathologists with tools for the approach to mass-directed liver biopsies clinically concerning for hepatocellular carcinoma. The examination of routine hematoxylin-eosin stains and the use of ancillary histochemical and immunohistochemical stains are discussed. Sections reviewing liver carcinoma with biphenotypic differentiation and the challenge of dysplastic nodules are included., (Copyright © 2015 Elsevier Inc. All rights reserved.)
- Published
- 2015
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