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2. The influence of bitter-taste receptor (TAS2R) expression in pharmacological response to Chloroquine in obese patients with COVID-19

Author

Lígia Moriguchi Watanabe, Natália Yumi Noronha, Carla Barbosa Nonino, Marcela Augusta de Souza Pinhel, and Izabella Ferreira Pires

Subjects
Medicine (General), medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Pneumonia, Viral, 030204 cardiovascular system & hematology, Affect (psychology), Receptors, G-Protein-Coupled, Betacoronavirus, 03 medical and health sciences, R5-920, 0302 clinical medicine, Chloroquine, Internal medicine, Pandemic, medicine, Humans, Obesity, 030212 general & internal medicine, Receptor, Pandemics, SARS-CoV-2, business.industry, Public health, COVID-19, General Medicine, medicine.disease, Bitter taste, COVID-19 Drug Treatment, Editorial, Coronavirus Infections, business, medicine.drug
Abstract

CONCLUSION The COVID-19 pandemic is a significant global public health challenge, especially concerning the pursuit of effective drugs for its prevention and treatment. Considering the prevalence of obesity worldwide and the complications associated with excessive body mass ratio, special attention should be given to patients with obesity. In a condition of obesity, reduced TAS2R expression could affect the response to medications such as CQ. Altogether, we highlighted the importance of obese patient care, particularly during the current COVID-19 pandemic. […] [...]

Published
2020

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