89 results
Search Results
52. Surgical Treatment for Severe Fixed Hyperkyphosis in an Adult Patient Suffering From Ankylosing Spondylitis and Hereditary Hypophosphatemia With Vertebral Osteopetrosis
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Julia M Wolfram, Emanuel Zitt, and Christian M Bach
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Adult ,Male ,medicine.medical_specialty ,medicine.medical_treatment ,Hereditary hypophosphatemia ,Thoracic Vertebrae ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Humans ,Orthopedics and Sports Medicine ,Spondylitis, Ankylosing ,Kyphosis ,Surgical treatment ,030222 orthopedics ,Ankylosing spondylitis ,Rehabilitation ,Posterior fusion ,Lumbar Vertebrae ,business.industry ,Osteopetrosis ,Surgical correction ,medicine.disease ,Surgery ,Spinal Fusion ,Neurology (clinical) ,Familial Hypophosphatemic Rickets ,business ,030217 neurology & neurosurgery ,Hypophosphatemia - Abstract
Purpose Ankylosing spondylitis and hereditary hypophosphatemia with long-term high dose supplementation of phosphorous and calcitriol can both lead to severe structural abnormalities of the vertebrae. Impairment of spinal mobility and spinal deformity may ultimately necessitate surgical treatment. A severe fixed hyperkyphosis in a patient with ankylosing spondylitis is a surgically demanding condition, therefore, the indication for surgical treatment should be thoroughly considered and chosen individually. Methods This is an uncommon case with a combination of a severe fixed hyperkyphosis with a Cobb-angle of 105 degrees between Th2 and L4 in an adult male patient suffering from ankylosing spondylitis and X-linked hypophosphatemia with surprisingly massive osteopetrosis. In this paper, the coexisting conditions of late-stage ankylosing spondylitis and long-term treated hereditary hypophosphatemia are highlighted. The surgical treatment with different techniques, complications, and results are well explained. Results A normal gait and stand were achieved by a long posterior fusion with 3 pedicle subtraction osteotomies on L1, L3, and L5. The surgical correction was performed in 3 stages. Postoperative the patient was administered to a rehabilitation center for 3 months. The hyperkyphosis, the C7 plumbline, and the pelvic retroversion were corrected. Conclusions Surgical treatment of a severe fixed hyperkyphosis due to ankylosing spondylitis is technically demanding but can be successfully achieved if all surgical challenges and comorbidities are adequately addressed including intraoperative surprising findings like osteopetrotic bone in a patient with hereditary hypophosphatemia as in our case.
- Published
- 2020
53. The Efficacy of Lumbar Hybrid Fusion for the Prevention of Adjacent Segment Disease: Fact or Artifact? A Meta-analysis
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Chi Heon Kim, Hyun Jae Cho, Chang Hyun Lee, Chun Kee Chung, Seung Heon Yang, Young San Ko, and Young Il Won
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medicine.medical_specialty ,Lumbar Vertebrae ,business.industry ,medicine.medical_treatment ,Lumbosacral Region ,Subgroup analysis ,Perioperative ,Odds ratio ,Intervertebral Disc Degeneration ,Confidence interval ,Surgery ,Oswestry Disability Index ,Lumbar ,Spinal Fusion ,Treatment Outcome ,Spinal fusion ,Meta-analysis ,medicine ,Humans ,Orthopedics and Sports Medicine ,Neurology (clinical) ,business ,Artifacts - Abstract
Study Design: A systematic literature review and meta-analysis Objective: The aim of this study is to compare hybrid constructs with traditional fusion-only constructs for the incidence of adjacent segment degeneration (ASDeg) and clinical outcomes in patients with degenerative lumbar diseases. Summary of Background Data: Spinal fusion is a standard surgery for various pathologies of the lumbar spine, which results in changes to the biomechanics of the spine, potentially leading to ASDeg. Although ASDeg can occur slowly as a natural course, early-onset ASDeg is regarded to be related to fusion surgery. Materials and Methods: A systematic search was conducted to identify studies that match the purpose. Included studies were compared using the incidence of ASDeg, Oswestry Disability Index, Visual Analog Score, and perioperative outcomes. We calculated the Peto odds ratio and mean difference (MD) for the continuous variables, respectively. In the hybrid group, subgroup analysis was also performed among devices. Results: Among 10 papers involving 767 patients, 372 patients underwent hybrid fusion and 395 patients underwent fusion-only. ASDeg occurred in 10.2% in the hybrid and 21.5% in the fusion-only group [Peto odds ratio, 0.39; 95% confidence interval (CI), 0.23-0.64]. The MD for Visual Analog Score were 0.45 (95% CI, 0.05-0.85) between 2 groups, which was statistically significant but was too small to have clinical significance. The MD for Oswestry Disability Index was 0.93 (95% CI, -1.016 to 2.872), which was not statistically different between 2 groups. The hybrid is superior for 18 minutes (95% CI, 5.78-30.72) shorter than typical surgery. Conclusions: Hybrid lumbar surgery decreased the incidence of early-onset ASDeg for about 2 years of follow-up. Among the hybrid constructs, the interspinous devices group accomplished favorable results with a lower risk. Adjacent segment disease was not as statistically significant as ASDeg, but adjacent segment disease may show a substantial difference for >2-year follow-up.
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- 2020
54. Lumbar Radiofrequency Ablation: Procedural Technique
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Junyoung Ahn, Mark F. Kurd, and David Stolzenberg
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medicine.medical_specialty ,Facet (geometry) ,Radiofrequency ablation ,Patient positioning ,Patient Positioning ,Zygapophyseal Joint ,law.invention ,Lumbar ,law ,Arthropathy ,medicine ,Humans ,Orthopedics and Sports Medicine ,Radiofrequency Ablation ,Lumbar Vertebrae ,business.industry ,medicine.disease ,Cannula ,Low back pain ,Surgery ,Conservative treatment ,Neurology (clinical) ,medicine.symptom ,Chronic Pain ,Joint Diseases ,business ,Low Back Pain - Abstract
Lumbar radiofrequency ablation is indicated for the treatment of chronic axial low back pain that is mediated by facet arthropathy which has failed more conservative treatment options. This article details proper equipment and medications, patient positioning and setup, step-by-step instructions for multiplanar fluoroscopic visualization, cannula placement, and postoperative management. Pearls and pitfalls are also discussed. In addition, an instructional procedure video (Supplemental Digital Content 1, http://links.lww.com/CLINSPINE/A90) accompanies this paper.
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- 2020
55. Propensity Score Matching: A Statistical Method
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Kristen Nicholson, Alexander R. Vaccaro, Liam T Kane, Dhruv K.C. Goyal, Gregory D. Schroeder, Taolin Fang, Matthew S. Galetta, and Christopher K. Kepler
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030222 orthopedics ,Matching (statistics) ,Computer science ,fungi ,Confounding ,Regression analysis ,03 medical and health sciences ,0302 clinical medicine ,Data Interpretation, Statistical ,Outlier ,Statistics ,Covariate ,Propensity score matching ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Observational study ,Orthopedic Procedures ,Neurology (clinical) ,Propensity Score ,030217 neurology & neurosurgery - Abstract
Propensity score matching (PSM) is a commonly used statistical method in orthopedic surgery research that accomplishes the removal of confounding bias from observational cohorts where the benefit of randomization is not possible. An alternative to multiple regression analysis, PSM attempts to reduce the effects of confounders by matching already treated subjects with control subjects who exhibit a similar propensity for treatment based on preexisting covariates that influence treatment selection. It, therefore, establishes a new control group by discarding outlier control subjects. This new control group reduces the unwanted influences of covariates, allowing for proper measurement of the intended variable. An example from orthopedic spine literature is discussed to illustrate how PSM may be applied in practice. PSM is uniquely valuable in its utility and simplicity, but it is limited in that it requires the removal of data and works primarily on binary treatments. In addition to matching, the propensity score can be used for stratification, covariate adjustments, and inverse probability of treatment weighting, but these topics are outside the scope of this paper. Personnel in the orthopedic field would benefit from learning about the function and application of this method given its common use in the orthopedic literature.
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- 2020
56. Ultrasound Lancet-aided Translaminar Posterior Lumbar Approach to the Recesso-Foraminal Area: Technical Note
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Alessandro Rustia, Mauro Palmieri, Alessandro Pesce, Alessandro Frati, and Giancarlo D'Andrea
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medicine.medical_specialty ,Ultrasound lancet ,translaminar posterior approach ,lumbar disc herniation ,Pars interarticularis ,Segmental instability ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Spinal canal ,Lumbar Vertebrae ,business.industry ,Ultrasound ,Lumbosacral Region ,Technical note ,Anatomy ,medicine.anatomical_structure ,Treatment Outcome ,Orthopedic surgery ,Lumbar approach ,Surgery ,Lumbar spine ,Neurology (clinical) ,business ,Spinal Canal ,Intervertebral Disc Displacement - Abstract
Extrusion and sequestration of the nucleus pulposus involving the spinal canal or the foramina/recesses complicates up to 28% of the lumbar disc herniations. The transpars/translaminar anatomical approach is well described and its advantages when handling with a lateral, foraminal extruded disc herniation are appreciated and recognized. Nevertheless, this approach presents several pitfalls such as the risk of disconnecting the pars interarticularis, which may cause segmental instability. This particular eventuality is because of the particular anatomical conformation of the pars interarticularis. Although already part of the modern surgical armamentarium for general, orthopedic, cranial and spinal surgeons, the use of the ultrasonic scalpel technique for such approach has never been discussed to date, to the best of our knowledge. The purpose of the present paper is therefore to introduce and describe the stepwise technique along with an extensive discussion of the facilitating role of the ultrasonic scalpel in the translaminar/transpars approach in the management of extruded disc herniation of the lumbar spine.
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- 2020
57. Thoracolumbar Spinal Cord Stimulator Trial: Procedural Technique
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Mayan Lendner, David Stolzenberg, Mark F. Kurd, and Junyoung Ahn
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medicine.medical_specialty ,Patient positioning ,Pain ,Patient Positioning ,law.invention ,Postoperative management ,03 medical and health sciences ,0302 clinical medicine ,Refractory ,law ,medicine ,Humans ,Orthopedics and Sports Medicine ,030222 orthopedics ,Postlaminectomy syndrome ,business.industry ,Laminectomy ,medicine.disease ,Spinal cord stimulator ,Surgery ,Conservative treatment ,Complex regional pain syndrome ,Spinal Cord ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Spinal cord stimulator trials are indicated for the treatment of postlaminectomy syndrome with persistent severe back and limb pain which has failed conservative treatment options and where no further surgery is indicated. They are also indicated for refractory complex regional pain syndrome. This article details patient positioning and set up, step-by-step instructions for the procedure and postoperative management. Pearls and pitfalls are also discussed. In addition, an instructional procedure video, Supplemental Digital Content 1 (http://links.lww.com/CLINSPINE/A121) accompanies this paper.
- Published
- 2019
58. Propensity Score Matching: A Powerful Tool for Analyzing Observational Nonrandomized Data
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Jetan H. Badhiwala, Brij S Karmur, and Jefferson R. Wilson
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030222 orthopedics ,medicine.medical_specialty ,Accurate estimation ,business.industry ,Confounding ,Confounding Factors, Epidemiologic ,Outcome (game theory) ,Treatment and control groups ,03 medical and health sciences ,0302 clinical medicine ,Clinical research ,Spine surgery ,Research Design ,Propensity score matching ,Physical therapy ,medicine ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Observational study ,Neurology (clinical) ,business ,Propensity Score ,030217 neurology & neurosurgery - Abstract
In using observational, nonrandomized data, there is often interest in studying the effect of a particular treatment on a specific outcome. However, the imbalance of potential confounding variables between the treatment groups can distort the relationship between treatment and outcome. Propensity score matching is one, increasingly utilized, method to help account for such imbalances, allowing for a more accurate estimation of the influence of treatment on outcome. In this paper, we provide the clinician with an overview of propensity score matching techniques and provide a practical example of how this has been used in clinical research relevant to spine surgery.
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- 2019
59. Percutaneous Nucleoplasty for the Treatment of a Contained Cervical Disk Herniation
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Hans A. Aukes, Frank J P M Huygen, Pravesh S. Gadjradj, John S. Soria van Hoeve, Biswadjiet S. Harhangi, Judith D de Rooij, Neurosurgery, and Anesthesiology
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medicine.medical_specialty ,Percutaneous ,Decompression ,Fast recovery ,cervical spine ,disk herniation ,nucleoplasty ,Anterior cervical discectomy ,03 medical and health sciences ,Cervical radiculopathy ,0302 clinical medicine ,Postoperative Complications ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Diskectomy, Percutaneous ,030212 general & internal medicine ,Surgical Technique ,Surgical treatment ,Postoperative Care ,business.industry ,Standard treatment ,Surgery ,Conservative treatment ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,minimally invasive ,Neurology (clinical) ,business ,030217 neurology & neurosurgery ,Intervertebral Disc Displacement - Abstract
Supplemental Digital Content is available in the text., Cervical radiculopathy is characterized by compression of the roots of the nerve. When conservative treatment fails and symptoms persist or increase in severity, surgical treatment is considered. Anterior cervical discectomy with or without fusion is regarded as the standard treatment for cervical disk herniation. Recently, there is an evolving trend in spinal surgery towards less invasive techniques. Nucleoplasty is a minimally invasive technique in which radiofrequency technology is used for percutaneous decompression. During the last years nucleoplasty has been proven to be a safe and effective treatment to alleviate radiculopathy, caused by a contained disk herniation. Nucleoplasty is usually performed on an outpatient basis and is associated with a fast recovery time. This paper will describe the preoperative and postoperative management of cervical nucleoplasty as well as the surgical technique, accompanied by a video.
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- 2017
60. Guidelines on How to Perform a Meta-Analysis in Spine Surgery: Strengths and Weaknesses of Design
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David Gendelberg, Casey Slattery, and Kushagra Verma
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030222 orthopedics ,Computer science ,MEDLINE ,Subject (documents) ,Guidelines as Topic ,Data science ,Spine ,Data set ,03 medical and health sciences ,0302 clinical medicine ,Spine surgery ,Meta-Analysis as Topic ,Meta-analysis ,Humans ,Orthopedics and Sports Medicine ,Surgery ,Neurology (clinical) ,030217 neurology & neurosurgery ,Strengths and weaknesses ,Statistician ,Randomized Controlled Trials as Topic - Abstract
There are many questions in the literature that remain unanswered due to the paucity of available subjects or the large sample size needed to detect a difference. A meta-analysis consists of integrating together data from multiple studies into one larger data set in order to increase the subject size and power of a paper. In essence, it is a systematic review in which one uses statistical methods to summarize the results of these studies. It is important that a meta-analysis be performed in a systematic and orderly manner with the assistance of a statistician. When carried out correctly, these studies serve as powerful tools to help us better address our knowledge. Because of their complexity, they are prone to bias at multiple levels. This article will discuss the steps involved in performing a meta-analysis, select good studies, as well as explain the statistics conducted in these studies. Furthermore, we will discuss examples from the literature that demonstrate a good meta-analysis.
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- 2018
61. How to Write Effective Discussion and Conclusion Sections
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Mayan Lendner, Carol Foltz, Alexander R. Vaccaro, and Gabriel Makar
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Biomedical Research ,030504 nursing ,business.industry ,Writing ,Section (typography) ,Guidelines as Topic ,Field (computer science) ,03 medical and health sciences ,0302 clinical medicine ,Spine surgery ,Publishing ,Orthopedics and Sports Medicine ,Surgery ,Engineering ethics ,Neurology (clinical) ,Meaning (existential) ,0305 other medical science ,business ,Psychology ,030217 neurology & neurosurgery - Abstract
With the exponential increase in research in the field of spine surgery, publishing peer-reviewed articles has become both more desirable and competitive in the past decade. Constructing an impactful manuscript has many important factors, one of which is a well-written Discussion section. A research study can ask a pressing question, have a meticulous methodology and report compelling results; however, without a thoughtful and well-informed analysis of the meaning of the study's findings and their potential influence on the field, the paper will be uninteresting and weak. Thus, formulating an effective Discussion section is crucial to improving the likelihood of the study's publication and its impact.
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- 2018
62. Fluoroscopically Guided Lumbar Transforaminal Epidural Steroid Injection: Procedural Technique
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Junyoung Ahn, Mark F. Kurd, and David Stolzenberg
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musculoskeletal diseases ,medicine.medical_specialty ,medicine.medical_treatment ,Patient positioning ,Injections, Epidural ,Patient Positioning ,Postoperative management ,03 medical and health sciences ,0302 clinical medicine ,Lumbar ,Medicine ,Fluoroscopy ,Humans ,Orthopedics and Sports Medicine ,030212 general & internal medicine ,Epidural steroid ,Lumbar Vertebrae ,medicine.diagnostic_test ,business.industry ,Epidural steroid injection ,medicine.disease ,Surgery ,Radicular pain ,Steroids ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Fluoroscopically guided lumbar transforaminal epidural steroid injections are indicated for the treatment of lumbar radicular pain that has failed more conservative options. This article details proper equipment and medications, patient positioning and set-up, step-by-step instructions for multiplanar fluoroscopic visualization, needle advancement and medication instillation, and postoperative management. Pearls and pitfalls are also discussed. In addition, an instructional procedure video accompanies this paper.
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- 2018
63. Heterogeneity of Reporting Outcomes in the Spine Surgery Literature
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Luke A. Torre-Healy, Maxwell Cooper, Samuel K. Cho, Michael P. Steinmetz, Vincent J. Alentado, Thomas E. Mroz, and Edward C. Benzel
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Research Report ,medicine.medical_specialty ,PubMed ,Depression scale ,Visual analogue scale ,03 medical and health sciences ,0302 clinical medicine ,Patient satisfaction ,Spine surgery ,Quality of life ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Depression (differential diagnoses) ,030222 orthopedics ,business.industry ,Background data ,Publications ,Spine ,Oswestry Disability Index ,Treatment Outcome ,Physical therapy ,Surgery ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
STUDY DESIGN Review of spine surgery literature between 2005 and 2014 to assess the reporting of patient outcomes by determining the variability of use of patient outcomes metrics in the following categories: pain and disability, patient satisfaction, readmission, and depression. OBJECTIVE Expose the heterogeneity of outcomes reporting and discuss current initiatives to create more homogenous outcomes databases. SUMMARY OF BACKGROUND DATA There has been a recent focus on the reporting of quality metrics associated with spine surgery outcomes. However, little consensus exists on the optimal metrics that should be used to measure spine surgery outcomes. MATERIALS AND METHODS A PubMed search of all spine surgery manuscripts from January 2005 through December 2014 was performed. Linear regression analyses were performed on individual metrics as well as outcomes categories as a fraction of total papers reviewing surgical outcomes. RESULTS Outcomes reporting has increased significantly between January 1, 2005 and December 31, 2014 [175/2871 (6.1%) vs. 764/5603 (13.6%), respectively; P
- Published
- 2018
64. Instability in Thoracolumbar Trauma: Is a New Definition Warranted?
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Apar S. Patel, Christina M. Walter, Kamran Sattarov, Salman Abbasi Fard, Mauricio J. Avila, Jesse Skoch, and Ali A. Baaj
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Joint Instability ,medicine.medical_specialty ,MEDLINE ,Classification scheme ,Thoracic Vertebrae ,03 medical and health sciences ,0302 clinical medicine ,Physical medicine and rehabilitation ,Deformity ,medicine ,Humans ,Orthopedics and Sports Medicine ,030222 orthopedics ,Lumbar Vertebrae ,business.industry ,Spinal instability ,Thoracolumbar spine ,Search terms ,Spinal Injuries ,Meta-analysis ,Spinal Fractures ,Surgery ,Neurology (clinical) ,medicine.symptom ,Medline database ,business ,030217 neurology & neurosurgery - Abstract
Study design Review of the articles. Objective The objective of this study was to review all articles related to spinal instability to determine a consensus statement for a contemporary, practical definition applicable to thoracolumbar injuries. Summary of background data Traumatic fractures of the thoracolumbar spine are common. These injuries can result in neurological deficits, disability, deformity, pain, and represent a great economic burden to society. The determination of spinal instability is an important task for spine surgeons, as treatment strategies rely heavily on this assessment. However, a clinically applicable definition of spinal stability remains elusive. Materials and methods A review of the Medline database between 1930 and 2014 was performed limited to papers in English. Spinal instability, thoracolumbar, and spinal stability were used as search terms. Case reports were excluded. We reviewed listed references from pertinent search results and located relevant manuscripts from these lists as well. Results The search produced a total of 694 published articles. Twenty-five articles were eligible after abstract screening and underwent full review. A definition for spinal instability was described in only 4 of them. Definitions were primarily based on biomechanical and classification studies. No definitive parameters were outlined to define stability. Conclusions Thirty-six years after White and Panjabi's original definition of instability, and many classification schemes later, there remains no practical and meaningful definition for spinal instability in thoracolumbar trauma. Surgeon expertise and experience remains an important factor in stability determination. We propose that, at an initial assessment, a distinction should be made between immediate and delayed instability. This designation should better guide surgeons in decision making and patient counseling.
- Published
- 2017
65. Microscope and Fiberscope-assisted Subarachnoid-Subarachnoid (S-S) Bypass: A Novel Surgical Technique to Reestablish Cerebrospinal Fluid Flow in Treating Dorsal Spinal Arachnoid Webs, Diagnosed by Cine-MRI
- Author
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Takayuki Shima, Yasushi Fujiwara, Nobuo Adachi, Bunichiro Izumi, and Hideki Manabe
- Subjects
Dorsum ,Male ,congenital, hereditary, and neonatal diseases and abnormalities ,Magnetic Resonance Imaging, Cine ,Spinal arachnoid ,Patient Positioning ,Subarachnoid Space ,030218 nuclear medicine & medical imaging ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Cerebrospinal fluid ,law ,Fiberscope ,Medicine ,Humans ,Orthopedics and Sports Medicine ,cardiovascular diseases ,Cerebrospinal Fluid ,Postoperative Care ,Microscopy ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,Anatomy ,Middle Aged ,Spinal cord ,medicine.disease ,nervous system diseases ,body regions ,medicine.anatomical_structure ,Treatment Outcome ,Spinal Cord ,Surgery ,Neurology (clinical) ,Subarachnoid space ,business ,Rheology ,030217 neurology & neurosurgery ,Syringomyelia - Abstract
A "dorsal spinal arachnoid web" is the thickened arachnoid band on the surface of the spinal cord which disturbs the cerebrospinal fluid (CSF) flow, known as a rare cause of thoracic myelopathy. The ideal treatment is controversial because of the risk of readhesion after simple resection of the web. A subarachnoid-subarachnoid bypass is a method to reestablish CSF flow through a silicon tube between the cranial and caudal subarachnoid space. This method is reported to be useful for traumatic syringomyelia, adhesive arachnoiditis, etc. We applied this technique for arachnoid webs with the assistance of a microscope and fiberscope. After a dura incision, the thickened arachnoid web can be seen fluttering within the CSF flow inside the arachnoid space, which partitions the subarachnoid space into cranial and caudal parts. After opening the subarachnoid space and resection of the web under a microscope, the fiberscope is inserted toward the cranial and caudal directions to check for the presence of another arachnoid web. If another web is found, it is penetrated using a guiding wire. Then, a silicone tube is inserted into the cranial and caudal normal subarachnoid space. In this paper, we would like to introduce this technique.
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- 2017
66. Transoral Closed Reduction of Fixed Atlanto-Axial Rotatory-Subluxation (AARS) in Childhood and Adolescence
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Markus Loibl, Daniel Haschtmann, Tamas F. Fekete, Dezsoe Jeszenszky, and Frank Kleinstück
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Male ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,Joint Dislocations ,Cervical spine injury ,03 medical and health sciences ,0302 clinical medicine ,030225 pediatrics ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Cervical Atlas ,Child ,Reduction (orthopedic surgery) ,Subluxation ,Mouth ,business.industry ,medicine.disease ,Cervical spine ,Surgery ,Spinal Fusion ,Atlanto-Axial Joint ,Minor trauma ,Spinal Injuries ,Cervical Vertebrae ,Cervical collar ,Female ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
Atlanto-axial rotatory-subluxation (AARS) is the most common pediatric cervical spine injury. Patients usually present with contralateral rotation and inclination of the upper cervical spine after minor trauma, or associated with an infection of the upper respiratory tract. According to the authors, initial management of patients with acute and chronic AARS type I-II should comprise closed reduction and immobilization with a cervical collar or a Halo-Body-Jacket. Surgical options of open reduction or C1/2 fusion should be restricted to irreducible or recurrent subluxations. This paper reviews the detailed technique of transoral closed reduction of AARS, as well as the preoperative and postoperative considerations.
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- 2017
67. Subsidizing the Sick: How Community Rating Works
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Alok D. Sharan, Praveen V. Mummaneni, Michael S Virk, and Anthony M DiGiorgio
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Tobacco use ,Actuarial science ,Insurance, Health ,Patient Protection and Affordable Care Act ,Community Participation ,Subsidy ,030204 cardiovascular system & hematology ,Repeal ,Insurance Coverage ,United States ,03 medical and health sciences ,Insurance premium ,0302 clinical medicine ,Community rating ,Humans ,Orthopedics and Sports Medicine ,Surgery ,030212 general & internal medicine ,Neurology (clinical) - Abstract
Insurance premium rates have typically been calculated using a variety of rating algorithms. Passage of the Patient Protection and Affordable Care Act mandated that all individual and small group plans must use the community rating method. This method gives the same insurance rate to all members of a community, with adjustments only being allowed based on age, geography, and tobacco use. This effectively raises rates on low-risk individuals to subsidize high-risk individuals. With President Trump and Congressional Republicans vowing to repeal the Patient Protection and Affordable Care Act, this lesser-known but controversial portion of the law may be abolished. This paper will review the various rating methods used by insurance companies in determining premiums.
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- 2017
68. Spinopelvic Alignment by Different Surgical Methods in the Treatment of Degenerative Sagittal Imbalance of the Lumbar Spine
- Author
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Dong-Gune Chang, Eun-Whan Lee, Kee-Yong Ha, and Young Hoon Kim
- Subjects
Pelvic tilt ,Male ,medicine.medical_specialty ,Visual analogue scale ,medicine.medical_treatment ,Osteotomy ,Surgical methods ,Pelvis ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Postural Balance ,Aged ,Orthodontics ,030222 orthopedics ,Lumbar Vertebrae ,business.industry ,Pelvic incidence ,Middle Aged ,Sagittal plane ,Surgery ,Oswestry Disability Index ,medicine.anatomical_structure ,Treatment Outcome ,Lumbar spine ,Female ,Neurology (clinical) ,business ,030217 neurology & neurosurgery - Abstract
A retrospective comparative study.To compare pedicle subtraction osteotomy (PSO) and iliac fixation (ILF) without osteotomy as methods of correcting lumbar spine deformities due to degenerative sagittal imbalance (DSI) through the evaluation of the changes in spinopelvic alignment.Many papers have reported the surgical results after PSO and ILF for patients with fixed adult deformities. However, little is known about the difference between PSO and ILF corrections of spinopelvic alignment in adults with DSI.DSI patients who had undergone PSO or ILF with a minimum of 2-year follow-up (FU) were retrospectively studied in PSO (n=30) or ILF (n=25) groups. Lumbar lordosis (LL), thoracic kyphosis (TK), and sagittal vertical axis (SVA) were measured as spinal parameters and pelvic incidence (PI), sacral slope (SS), and pelvic tilt (PT) were used as measurements of pelvic parameters. Clinical outcomes were evaluated using a visual analogue scale (VAS) and Oswestry Disability Index (ODI) scores.There were no statistically significant differences between the PSO and ILF groups with regard to age and fused segments, but there were significant differences in operative time and estimated blood loss. Concerning spinal parameters, there were significant increases of LL and TK in PSO group immediate postoperatively (LL: P=0.014, TK: P=0.017) and at the 2-year FU (LL: P=0.021, TK: P=0.022), but no significant difference in SVA was evident between the 2 groups. Within the pelvic parameters, there was a significant increase of SS and decrease of PT in the ILF group immediate postoperatively (SS: P=0.013, PT: P=0.009) and at the 2-year FU (SS: P=0.024, PT: P=0.027), but the PI in both groups was not changed after surgery and there was no significant difference between 2 groups. VAS and ODI were significantly improved after surgery in both groups.The PSO group was better than the ILF group in the correction of the LL and TK, but not with regard to the pelvic parameters. The ILF group was superior in the correction of the pelvic orientation as compared with the PSO group when the PI was constant after surgery. Ultimately, ILF effectively achieves better correction of the pelvic parameters (SS and PT).
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- 2017
69. Etiology of Adult-onset Stress Fracture in the Lumbar Spine
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Akira Dezawa, Toshinori Sakai, Koichi Sairyo, and Fumitake Tezuka
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musculoskeletal diseases ,Adult ,Male ,medicine.medical_specialty ,Tomography Scanners, X-Ray Computed ,Fractures, Stress ,Spondylolysis ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Lumbar ,Pars interarticularis ,medicine ,Humans ,Orthopedics and Sports Medicine ,Young adult ,Retrospective Studies ,Orthodontics ,030222 orthopedics ,Stress fractures ,Lumbar Vertebrae ,business.industry ,medicine.disease ,Magnetic Resonance Imaging ,Surgery ,Athletic Injuries ,Etiology ,Fracture (geology) ,Lumbar spine ,Female ,Neurology (clinical) ,business ,Low Back Pain ,030217 neurology & neurosurgery - Abstract
This study was a case series.The purpose of this paper was to present a case series of fresh stress fractures (spondylolysis) in the lumbar spines of adult athletes.Lumbar spondylolysis is a stress fracture of the pars interarticularis, which is generally considered a disease of children or adolescence. There is only 1 case series written in English reporting on adult-onset fresh spondylolysis.Eleven patients aged 20-27 years are included in this case series. A retrospective analysis was made of events that may cause stress fracture such as traumatic episodes or sports activities, spinal level, radiologic findings, stage of spondylolysis, treatment, and prognosis.Among the 11 patients, two had bilateral early-stage spondylolysis, 7 had unilateral early-stage spondylolysis and 2 had unilateral progressive-stage spondylolysis. Three occurred subsequent to a preexisting terminal-stage spondylolysis in the contralateral side, 1 occurred subsequent to a terminal-stage spondylolysis at the adjacent spinal level, and 1 occurred subsequent to a terminal-stage spondylolysis at a distant level. Thirteen pedicles adjacent to the pars interarticularis in the 11 patients showed bone marrow edema-like signal on magnetic resonance imaging. Six spondylolyses were found at L5, 2 each at L3 and L4, and 1 spondylolysis at L2. The 11 patients were divided into 4 groups according to suspected pathogenic mechanism: preexistent spondylolysis in the contralateral side, alteration of the athletic event, apparent traumatic episode, and others. Conservative treatment was prescribed for return to sports in all cases. Although 1 patient retired because of persistent low back pain, the remaining 10 patients returned to competition.Although lumbar spondylolysis is generally recognized to occur in childhood or adolescence, fresh lumbar spondylolysis should be included in the differential diagnosis of adult low back pain when patients are high-level athletes. Conservative treatment should be attempted for adult patients.
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- 2017
70. Microdiscectomy for a Paracentral Lumbar Herniated Disk
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Christopher K. Kepler, Jason W. Savage, Gregory D. Schroeder, Paul W. Millhouse, Mark F. Kurd, and Alexander R. Vaccaro
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Weakness ,medicine.medical_specialty ,Lumbar Vertebrae ,business.industry ,Radiography ,Leg pain ,Severity of Illness Index ,Lumbar herniated disk ,Surgery ,Intervertebral disk ,Lumbar ,Postoperative Complications ,Severity of illness ,medicine ,Humans ,Minimally Invasive Surgical Procedures ,Orthopedics and Sports Medicine ,Neurology (clinical) ,medicine.symptom ,business ,Microdissection ,Intervertebral Disc Displacement - Abstract
Lumbar disk herniations occur frequently and are often associated with leg pain, weakness, and paresthesias. Fortunately, the natural outcomes of radiculopathy due to a disk herniation are generally favorable, and the vast majority of patients improve with nonoperative care. Surgical intervention is reserved for patients who have significant pain that is refractory to at least 6 weeks of conservative care, patients who have a severe or progressive motor deficit, or patients who have any symptoms of bowel or bladder dysfunction. This paper reviews the preoperative and postoperative considerations, as well as the surgical technique, for a microdiscectomy for a lumbar intervertebral disk herniation.
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- 2015
71. Intraoperative Neural Mobility and Postoperative Neurological Recovery in Anterior Cervical Decompression Surgery: Evaluation With Intraoperative Sonography
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Shinya Katoh, Masashi Hachiya, Soichi Kondo, Hisanori Mihara, and Masatoshi Ono
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musculoskeletal diseases ,Adult ,Male ,medicine.medical_specialty ,Cord ,Nerve root ,Intraoperative Neurophysiological Monitoring ,Decompression ,Pulsatile flow ,Severity of Illness Index ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Compressive myelopathy ,Recovery rate ,Monitoring, Intraoperative ,Medicine ,Humans ,Orthopedics and Sports Medicine ,Aged ,Ultrasonography ,030222 orthopedics ,business.industry ,Recovery of Function ,Middle Aged ,Spinal cord ,Decompression, Surgical ,Surgery ,medicine.anatomical_structure ,Anesthesia ,Cervical decompression ,Cervical Vertebrae ,Female ,Neurology (clinical) ,business ,Spinal Cord Compression ,030217 neurology & neurosurgery - Abstract
STUDY DESIGN A study using intraoperative sonography (IOS) was conducted for evaluating neural mobility in anterior cervical decompression surgery. OBJECTIVES To analyze decompression status and mobility of the spinal cord and the nerve root during anterior cervical decompression and to clarify its relevance to the postoperative neurological recovery. SUMMARY OF BACKGROUND DATA Several papers introduced the usefulness of IOS assessments; however, there have been no reports systematically evaluating the neural mobility in anterior cervical decompression surgery. METHODS Eighty-four consecutive patients with compressive myelopathy who underwent anterior cervical decompression procedures were studied. The decompression status of the spinal cord was evaluated with IOS and classified into 3 grades according to the restoration pattern of the space ventral to the cord. Pulsatile motion of the spinal cord in cranio-caudal direction was named "sliding pulsation" and graded into 3 groups. The nerve root pulsation was also assessed using the IOS short-axis views. This study analyzed whether those neural mobility in anterior cervical decompression surgery had relevance to postoperative neurological recovery, which was assessed by the Japan Orthopaedic Association score. RESULTS The mean recovery rate of the Japan Orthopaedic Association score was 59.1% in total. According to the decompression status in IOS, 67 patients who acquired space ventral to the spinal cord indicated 64.3% of the recovery rate which was significantly higher than 36.6% of the other patients on an average. As to the sliding pulsation of the cord, 10 patients who failed to show this particular motion indicated significantly lower recovery rate as 36.9%. In addition, 6 patients who did not exhibit nerve root pulsation indicated just 29.3% of recovery rate, and 4 of them failed to show the cord sliding motion. CONCLUSIONS Sonographic evaluation during anterior cervical decompression surgery provided very useful information of neural decompression status that had significant correlation with postoperative neurological recovery.
- Published
- 2012
72. How to Write an Abstract.
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Meade MH, Michael M, Henzes J, Nanavati R, and Woods B
- Abstract
The abstract of a research paper functions to attract readers and highlight the clinical significance of a research project in a broadly appealing manner. Abstract structure is commonly dictated by the target journal, however, a basic style typically follows the "Introduction, Methods, Results and Discussion" structure of introduction, materials/methods, results, and discussion/conclusion. The abstract itself is commonly the initial accessible portion of a research paper, so writing in an engaging while informative manner is imperative for increasing manuscript views and citations. Overall, an abstract is a to-the-point synopsis of a research project that succinctly describes the entirety of your work., Competing Interests: The authors declare no conflict of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2024
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73. Global Trends of Researches on Lumbar Spinal Stenosis: A Bibliometric and Visualization Study.
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Yin M, Wang H, Sun Y, Xu C, Ye J, Ma J, Wang D, and Mo W
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- Bibliometrics, Humans, Publications, Quality of Life, Spine, Spinal Stenosis surgery
- Abstract
Study Design: Bibliometric and visualization analysis., Objective: Lumbar spinal stenosis (LSS) has become a common health problem and the most frequent indication for spinal surgery. This study aimed to illustrate the overall knowledge structure, and development trends of LSS, using a bibliometric analysis and newly developed visualization tools., Materials and Methods: Research data sets were acquired from the Web of Science. The time span was defined as "2000-2019". VOS viewer and Citespace software was provided to analyze the data and generate visualization knowledge maps. Annual trend of publications, distribution, H-index status, co-authorship status and research hotspots were analyzed., Results: A total of 1934 publications met the requirement. The United States published most papers (521, 26.9%), both total citations (17,626) and H-index (61) ranked first of all the countries. The most productive organizations on LSS is Seoul National University (50). Spine (43) published the most papers on LSS. Quality of life, risk factor, disability, double blind trials, and decompression surgery are the research hotspots in the recent years., Conclusion: The number of publications showed an upward trend with a stable rise in recent years. The United States is a country with the highest productivity, not only in quality, but also in quantity. Seoul National University has been the largest contributor in this field. Spine is the best journal related to LSS. Quality of life, risk factor, disability, and decompression surgery are the research hotspots in the recent years. Indeed, this study provides a new insight to the growth and development of LSS. Moreover, it will contribute to the growth of the international frontier of LSS., Competing Interests: The authors declare no conflict of interest., (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
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- 2022
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74. Comparing Surgical Treatments for Spondylolysis: Review on Current Research.
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Tarpada SP, Kim D, Levine NL, Morris MT, and Cho W
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- Adult, Humans, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae surgery, Treatment Outcome, Young Adult, Spondylolysis diagnostic imaging, Spondylolysis surgery
- Abstract
Study Design: Narrative review., Objective: To compare the various surgical methods of repairing spondylolysis defects in regard to improving pain, restoration of function, radiographic improvement, and complication rate., Summary of Background Data: Spondylolysis is a defect in the pars interarticularis of the vertebral arch, typically in the lumbar vertebra. Treatment can be nonoperative and/or surgical. There are various types of surgical repair including spinal compression, fusion, and direct pars repair., Methods: A comprehensive review of the English literature was performed utilizing Medline, Embase, and Web of Science. Inclusion criteria included papers or abstracts that evaluated the surgical techniques. Exclusion criteria included non-English-language papers or abstracts with inadequate information about outcomes., Results: Postoperative pain levels and patient function were consistently improved, regardless of surgical technique chosen. Positive clinical outcomes after surgery were seen more often in patients under age 20 and those who underwent minimally invasive repairs. Positive radiographic improvements were reported broadly, although some reported higher rates of nonunion with spinal compression. Complication rates were low throughout and minimally invasive techniques reported decreased blood loss and shorter hospital stays., Conclusions: Present surgical options appear largely comparable in terms of their ability to provide meaningful treatment for spondylolysis where conservative treatments have failed or otherwise remain unattempted., Competing Interests: The authors declare no conflict of interest., (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2021
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75. The Efficacy of Lumbar Hybrid Fusion for the Prevention of Adjacent Segment Disease: Fact or Artifact? A Meta-analysis.
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Cho HJ, Ko YS, Won YI, Lee CH, Yang SH, Kim CH, and Chung CK
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- Artifacts, Humans, Lumbar Vertebrae surgery, Lumbosacral Region, Treatment Outcome, Intervertebral Disc Degeneration surgery, Spinal Fusion adverse effects
- Abstract
Study Design: A systematic literature review and meta-analysis., Objective: The aim of this study is to compare hybrid constructs with traditional fusion-only constructs for the incidence of adjacent segment degeneration (ASDeg) and clinical outcomes in patients with degenerative lumbar diseases., Summary of Background Data: Spinal fusion is a standard surgery for various pathologies of the lumbar spine, which results in changes to the biomechanics of the spine, potentially leading to ASDeg. Although ASDeg can occur slowly as a natural course, early-onset ASDeg is regarded to be related to fusion surgery., Materials and Methods: A systematic search was conducted to identify studies that match the purpose. Included studies were compared using the incidence of ASDeg, Oswestry Disability Index, Visual Analog Score, and perioperative outcomes. We calculated the Peto odds ratio and mean difference (MD) for the continuous variables, respectively. In the hybrid group, subgroup analysis was also performed among devices., Results: Among 10 papers involving 767 patients, 372 patients underwent hybrid fusion and 395 patients underwent fusion-only. ASDeg occurred in 10.2% in the hybrid and 21.5% in the fusion-only group [Peto odds ratio, 0.39; 95% confidence interval (CI), 0.23-0.64]. The MD for Visual Analog Score were 0.45 (95% CI, 0.05-0.85) between 2 groups, which was statistically significant but was too small to have clinical significance. The MD for Oswestry Disability Index was 0.93 (95% CI, -1.016 to 2.872), which was not statistically different between 2 groups. The hybrid is superior for 18 minutes (95% CI, 5.78-30.72) shorter than typical surgery., Conclusions: Hybrid lumbar surgery decreased the incidence of early-onset ASDeg for about 2 years of follow-up. Among the hybrid constructs, the interspinous devices group accomplished favorable results with a lower risk. Adjacent segment disease was not as statistically significant as ASDeg, but adjacent segment disease may show a substantial difference for >2-year follow-up., Competing Interests: The authors declare no conflict of interest., (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2021
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76. Thoracolumbar Spinal Cord Stimulator Trial: Procedural Technique.
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Stolzenberg D, Ahn JJ, Lendner M, and Kurd M
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- Humans, Patient Positioning, Spinal Cord, Laminectomy, Pain
- Abstract
Spinal cord stimulator trials are indicated for the treatment of postlaminectomy syndrome with persistent severe back and limb pain which has failed conservative treatment options and where no further surgery is indicated. They are also indicated for refractory complex regional pain syndrome. This article details patient positioning and set up, step-by-step instructions for the procedure and postoperative management. Pearls and pitfalls are also discussed. In addition, an instructional procedure video, Supplemental Digital Content 1 (http://links.lww.com/CLINSPINE/A121) accompanies this paper., Competing Interests: The authors declare no conflict of interest., (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2021
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77. Propensity Score Matching: A Powerful Tool for Analyzing Observational Nonrandomized Data.
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Badhiwala JH, Karmur BS, and Wilson JR
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- Confounding Factors, Epidemiologic, Humans, Propensity Score, Research Design
- Abstract
In using observational, nonrandomized data, there is often interest in studying the effect of a particular treatment on a specific outcome. However, the imbalance of potential confounding variables between the treatment groups can distort the relationship between treatment and outcome. Propensity score matching is one, increasingly utilized, method to help account for such imbalances, allowing for a more accurate estimation of the influence of treatment on outcome. In this paper, we provide the clinician with an overview of propensity score matching techniques and provide a practical example of how this has been used in clinical research relevant to spine surgery., Competing Interests: The authors declare no conflict of interest., (Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2021
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78. Does Pedicle Screw Fixation Assisted by O-Arm Navigation Perform Better Than Fluoroscopy-guided Technique in Thoracolumbar Fractures in Percutaneous Surgery?: A Retrospective Cohort Study.
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Lu J, Chen W, Liu H, Yang H, and Liu T
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- Adult, Aged, Aged, 80 and over, Female, Fluoroscopy methods, Fracture Fixation, Internal methods, Humans, Male, Middle Aged, Prosthesis Failure, Reproducibility of Results, Retrospective Studies, Young Adult, Fluoroscopy instrumentation, Fracture Fixation, Internal instrumentation, Lumbar Vertebrae surgery, Pedicle Screws, Spinal Fractures surgery, Thoracic Vertebrae surgery
- Abstract
Study Design: A retrospective cohort study., Objective: To evaluate the effect of O-arm navigation in percutaneous surgeries for thoracolumbar fracture in comparison to the use of conventional fluoroscopic technique., Summary of Background Data: O-arm navigation is a progressive surgical tool, with extensive research papers reporting its effects. Whereas, there were not many papers describing its accuracy and facet impingement rate when compared with fluoroscopy-guided technique in percutaneous surgeries, especially at varying fracture levels., Materials and Methods: We conducted a retrospective comparative study of 97 consecutive patients of single-level neurological intact thoracolumbar fractures from November 2015 to October 2017 and they were all treated with percutaneous pedicle screw implantation. Screws were classified as 4 grades of perforations and 3 grades of facet joint violation. The association between variables such as anatomic perforation, functional perforation, and facet impingement were investigated by χ test, Fisher exact test or t test. A P-value of <0.05 was considered statistically significant., Results: A total of 573 pedicle screws were implanted and graded. The overall anatomic perforation rate and functional perforation rate were lower in the O-arm group compared with the fluoroscopy group (8.3% vs. 15.0%, P=0.013, 1.1% vs. 4.2%, P=0.024). At fracture level, the rate of grade 2 perforation of the O-arm group was lower than that of the fluoroscopy group (0% vs. 6.1%, P=0.033). Furthermore, the O-arm group obviously reduced the facet impingement rate both at all levels and at fracture levels (P=0.002; 0.02)., Conclusions: In percutaneous pedicle screw placement for neurological intact thoracolumbar fracture, the introduction of O-arm navigation improved accuracy, reduced functional perforations, and minimized serious perforations compared with conventional fluoroscopic technique. It also decreased facet joint violation observably and helped to prevent development of adjacent segment degeneration.
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- 2020
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79. Propensity Score Matching: A Statistical Method.
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Kane LT, Fang T, Galetta MS, Goyal DKC, Nicholson KJ, Kepler CK, Vaccaro AR, and Schroeder GD
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- Humans, Data Interpretation, Statistical, Orthopedic Procedures, Propensity Score
- Abstract
Propensity score matching (PSM) is a commonly used statistical method in orthopedic surgery research that accomplishes the removal of confounding bias from observational cohorts where the benefit of randomization is not possible. An alternative to multiple regression analysis, PSM attempts to reduce the effects of confounders by matching already treated subjects with control subjects who exhibit a similar propensity for treatment based on preexisting covariates that influence treatment selection. It, therefore, establishes a new control group by discarding outlier control subjects. This new control group reduces the unwanted influences of covariates, allowing for proper measurement of the intended variable. An example from orthopedic spine literature is discussed to illustrate how PSM may be applied in practice. PSM is uniquely valuable in its utility and simplicity, but it is limited in that it requires the removal of data and works primarily on binary treatments. In addition to matching, the propensity score can be used for stratification, covariate adjustments, and inverse probability of treatment weighting, but these topics are outside the scope of this paper. Personnel in the orthopedic field would benefit from learning about the function and application of this method given its common use in the orthopedic literature.
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- 2020
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80. Bibliometric Analysis of the 100 Most Cited Articles on Intervertebral Disk Research: From 1900 to 2017 Year.
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Yang G, Li Z, Ye W, Huang S, Liu S, Liu K, and Tan Q
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- Humans, Bibliometrics, Biomedical Research, Intervertebral Disc, Periodicals as Topic
- Abstract
Study Design: A bibliometric review of the literature., Object: To analyze and quantify the most frequently cited papers in intervertebral disk research., Summary of Background Data: The number of citations that a paper has received reflects its impact in related research area. In the field of disk research, however, it remains unknown which papers are most cited. By searching related literature databases, we identified the most cited 100 articles that advanced the understanding of the intervertebral disk to provide a historic view of scientific research of the disk., Materials and Methods: Intervertebral disk original research-related publications from January 1, 1900 to December 31, 2017 were retrieved from the Web of Science database. Each retrieved article was analyzed using the Cited Reference Search tool to identify the most cited articles. The number of citations, year of publication, publishing journal, authorship, country of publication, and the knowledge maps of keywords were gathered and generated., Results: The number of citations of the 100 selected articles ranges from 209 to 1269, and they were published from 1953 to 2009. Basic research is the most common type of study (n=60), followed by epidemiological study (n=40). Spine published 57 of the most cited 100 papers. The greatest contribution came from the United States of America (n=41), followed by the United Kingdom (n=18) and Japan (n=9). Frequently appearing keywords classified into 3 clusters: "biological study," "clinical study," and "imageological study." The keyword "degeneration" was mentioned the most, 51 items, and the word "development" was the latest hot spot in the most cited articles., Conclusions: In the field of disk research, some papers were heavily cited more than 100 times, suggesting these studies have substantially contributed to the body of knowledge of the intervertebral disk and findings were widely accepted by related clinicians and scientists.
- Published
- 2020
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81. Heterogeneity of Reporting Outcomes in the Spine Surgery Literature.
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Cooper ME, Torre-Healy LA, Alentado VJ, Cho S, Steinmetz MP, Benzel EC, and Mroz TE
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- Humans, PubMed, Publications, Treatment Outcome, Research Report, Spine surgery
- Abstract
Study Design: Review of spine surgery literature between 2005 and 2014 to assess the reporting of patient outcomes by determining the variability of use of patient outcomes metrics in the following categories: pain and disability, patient satisfaction, readmission, and depression., Objective: Expose the heterogeneity of outcomes reporting and discuss current initiatives to create more homogenous outcomes databases., Summary of Background Data: There has been a recent focus on the reporting of quality metrics associated with spine surgery outcomes. However, little consensus exists on the optimal metrics that should be used to measure spine surgery outcomes., Materials and Methods: A PubMed search of all spine surgery manuscripts from January 2005 through December 2014 was performed. Linear regression analyses were performed on individual metrics as well as outcomes categories as a fraction of total papers reviewing surgical outcomes., Results: Outcomes reporting has increased significantly between January 1, 2005 and December 31, 2014 [175/2871 (6.1%) vs. 764/5603 (13.6%), respectively; P<0.001; R=98.1%]. For the category of pain and disability reporting, Visual Analog Score demonstrated a statistically significant decrease in use from 2005 through 2014 [56/76 (73.7%) vs. 300/520 (57.7%), respectively; P<0.001], whereas Oswestry Disability Index increased significantly in use [19/76 (25.0%) vs. 182/520 (35.0%), respectively; P<0.001]. For quality of life, EuroQOL-5 Dimensions increased significantly in use between 2005 and 2014 [4/23 (17.4%) vs. 30/87 (34.5%), respectively; P<0.01]. In contrast, use of 36 Item Short Form Survey significantly decreased [19/23 (82.6%) vs. 57/87 (65.5%), respectively; P<0.01]. For depression, only the Zung Depression Scale underwent a significant increase in usage between 2005 and 2014 [0/0 (0%) vs. 7/13 (53.8%), respectively; P<0.01]., Conclusions: Although spine surgery outcome reporting has increased significantly over the past 10 years, there remains considerable heterogeneity in regards to individual outcomes metrics utilized. This heterogeneity makes it difficult to compare outcomes across studies and to accurately extrapolate outcomes to clinical practice.
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- 2018
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82. A Comprehensive Meta-Analysis of the Adjacent Segment Parameters in Cervical Disk Arthroplasty Versus Anterior Cervical Discectomy and Fusion.
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Dong L, Wang D, Chen X, Liu T, Xu Z, Tan M, and Hao D
- Subjects
- Cervical Vertebrae physiopathology, Humans, Publication Bias, Range of Motion, Articular, Arthroplasty, Cervical Vertebrae surgery, Diskectomy, Spinal Fusion
- Abstract
Study Design: This is a meta-analysis of controlled trials., Objective: To assess the overall condition of adjacent segment of cervical disk arthroplasty (CDA) compared with anterior cervical discectomy and fusion (ACDF)., Summary of Background Data: With the increase in CDA and ACDF, surgeons are taking more attention to adjacent segment degeneration (ASDeg) and adjacent segment disease (ASDis). There are more and more meta-analyses comparing the efficacy of CDA with ACDF, however, there are few meta-analyses referring to adjacent segment parameters, and investigators are still unable to arrive at the same conclusion., Methods: Several important databases were searched for controlled trials comparing CDA and ACDF before February 2016 according to PRISMA guidelines. The analysis parameters included follow-up time, operative segments, cervical range of motion (ROM), adjacent segment motion, ASDeg, ASDis and adjacent segment reoperation. The risk of bias scale and Newcastle-Ottawa Scale were used to assess the papers. Subgroup analysis and sensitivity analysis were used to analyze the reason for high heterogeneity., Results: Forty-one controlled trials fulfilled the inclusion criteria, including 36 English papers and 5 Chinese. The average follow-up time of all included patients was 39 months. Compared with ACDF, the rate of adjacent segment reoperation in the CDA group was significantly lower (P<0.01), and the advantage of CDA group increased with the increasing of follow-up time according to subgroup analysis. The rate of ASDeg in CDA was significantly lower than that of ACDF (P<0.01). There was no statistical difference between upper and lower ASDeg using the same surgical method (P>0.05). CDA provided a greater cervical ROM than did ACDF (P<0.01). There was a lower adjacent segment ROM and the rate of ASDis in CDA compared with ACDF (P<0.05)., Conclusions: Compared with ACDF, the advantages of CDA were lower ASDeg, ASDis, adjacent segment reoperation and adjacent segment motion; and higher cervical ROM. However, there was no statistical difference between upper and lower adjacent segment ROM/ASDeg using the same surgery.
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- 2018
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83. Metastatic Spinal Cord Compression and Steroid Treatment: A Systematic Review.
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Kumar A, Weber MH, Gokaslan Z, Wolinsky JP, Schmidt M, Rhines L, Fehlings MG, Laufer I, Sciubba DM, Clarke MJ, Sundaresan N, Verlaan JJ, Sahgal A, Chou D, and Fisher CG
- Subjects
- Humans, Randomized Controlled Trials as Topic, Steroids administration & dosage, Treatment Outcome, Spinal Cord Compression drug therapy, Spinal Neoplasms drug therapy, Spinal Neoplasms secondary, Steroids therapeutic use
- Abstract
Study Design: Systematic review., Objectives: We conducted a systematic review of the literature to answer the following questions regarding the use of steroid therapy in metastatic spinal cord compression (MSCC): 1. In cases of MSCC, what is the effect of steroid administration before definitive radiotherapy or surgery on ambulatory status, bowel and bladder function and survival? 2. What steroid dosing regimens are associated with the best outcomes concerning neurological symptoms and complication prevention in cases of MSCC?, Summary of Background Data: Currently, there is significant variation in the initial bolus dose, daily maintenance dose and duration of treatment when steroids are used as a bridge to definitive therapy for MSCC., Methods: A literature search following PRISMA guidelines was conducted in June 2016, using Medline via Ovid SP, Medline via PubMed, Embase, Biosis Previews and the Cochrane Library. Search terms used in each database varied slightly to optimize results. All generic steroid formulations were included along with spinal cord compression or myelopathy combined with metastatic or malignant tumors. Papers discussing acute traumatic causes of spinal cord compression were excluded, as were papers discussing cord compression from nonmetastatic tumors or epidural lipomatosis. Subjects were limited to adult humans undergoing definitive treatment with radiotherapy or surgery., Results: Of the 309 papers retrieved, 66 full text studies were reviewed and 6 papers were found to address the stated questions., Conclusions: There is a paucity of high quality literature evaluating the use of steroids in MSCC. On the basis of the evidence available an initial 10 mg intravenous bolus of dexamethasone followed by 16 mg PO QD has been associated with fewer complications compared with 100 mg bolus and 96 mg QD. Weaning of steroids should occur rapidly after definitive treatment. Risk of gastric bleeding or perforation can be managed with the routine use of proton-pump inhibitors., Level of Evidence: Level IIIa.
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- 2017
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84. Spinopelvic Alignment by Different Surgical Methods in the Treatment of Degenerative Sagittal Imbalance of the Lumbar Spine.
- Author
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Chang DG, Ha KY, Kim YH, and Lee EW
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- Aged, Female, Humans, Male, Middle Aged, Postoperative Complications etiology, Treatment Outcome, Lumbar Vertebrae physiopathology, Lumbar Vertebrae surgery, Pelvis physiopathology, Pelvis surgery, Postural Balance
- Abstract
Study Design: A retrospective comparative study., Objective: To compare pedicle subtraction osteotomy (PSO) and iliac fixation (ILF) without osteotomy as methods of correcting lumbar spine deformities due to degenerative sagittal imbalance (DSI) through the evaluation of the changes in spinopelvic alignment., Summary of Background Data: Many papers have reported the surgical results after PSO and ILF for patients with fixed adult deformities. However, little is known about the difference between PSO and ILF corrections of spinopelvic alignment in adults with DSI., Methods: DSI patients who had undergone PSO or ILF with a minimum of 2-year follow-up (FU) were retrospectively studied in PSO (n=30) or ILF (n=25) groups. Lumbar lordosis (LL), thoracic kyphosis (TK), and sagittal vertical axis (SVA) were measured as spinal parameters and pelvic incidence (PI), sacral slope (SS), and pelvic tilt (PT) were used as measurements of pelvic parameters. Clinical outcomes were evaluated using a visual analogue scale (VAS) and Oswestry Disability Index (ODI) scores., Results: There were no statistically significant differences between the PSO and ILF groups with regard to age and fused segments, but there were significant differences in operative time and estimated blood loss. Concerning spinal parameters, there were significant increases of LL and TK in PSO group immediate postoperatively (LL: P=0.014, TK: P=0.017) and at the 2-year FU (LL: P=0.021, TK: P=0.022), but no significant difference in SVA was evident between the 2 groups. Within the pelvic parameters, there was a significant increase of SS and decrease of PT in the ILF group immediate postoperatively (SS: P=0.013, PT: P=0.009) and at the 2-year FU (SS: P=0.024, PT: P=0.027), but the PI in both groups was not changed after surgery and there was no significant difference between 2 groups. VAS and ODI were significantly improved after surgery in both groups., Conclusions: The PSO group was better than the ILF group in the correction of the LL and TK, but not with regard to the pelvic parameters. The ILF group was superior in the correction of the pelvic orientation as compared with the PSO group when the PI was constant after surgery. Ultimately, ILF effectively achieves better correction of the pelvic parameters (SS and PT).
- Published
- 2017
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85. Generation and Development of Paravertebral Ossification in Cervical Artificial Disk Replacement: A Detailed Analytic Report Using Coronal Reconstruction CT.
- Author
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Tian W, Han X, Liu B, He D, Lv Y, and Yue J
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- Adult, Aged, Female, Follow-Up Studies, Humans, Male, Middle Aged, Range of Motion, Articular, Retrospective Studies, Treatment Outcome, Intervertebral Disc Degeneration diagnostic imaging, Intervertebral Disc Degeneration etiology, Ossification, Heterotopic diagnostic imaging, Ossification, Heterotopic etiology, Tomography, X-Ray Computed, Total Disc Replacement adverse effects
- Abstract
Study Design: A retrospective follow-up study and review of images in published papers., Objective: To determine whether true heterotopic ossification (HO) occurs in artificial disk replacement (ADR); to evaluate the incidence of paravertebral ossification (PO) and its influence on ADR., Summary of Background Data: HO is typically defined as the abnormal formation of true bone within extraskeletal soft tissues. However, HO in ADR does not fit this definition precisely, as it originates from vertebral body, making it hard to distinguish radiologically from preexisting osteophytes. In this study, the term used for bone formation around ADR is PO., Methods: First, all images in the published papers were evaluated as to whether the presented PO in ADR fit the classic definition of HO or osteophytes. Second, we studied 37 consecutive patients who underwent ADR and follow-up for minimum 24 months. The preoperative and follow-up incidence of PO and its influence on range of motion were evaluated using x-ray and computed tomography., Results: All 52 images of PO were found adjacent to the disk in 1 segment rather than entire cervical spine. Fifty (96.2%) of the POs were found to originate from the vertebral body rather than in the soft tissue. A total of 31 patients were included in the follow-up study. No significant difference was found in the incidence of PO between the follow-up and preoperation (61.29% vs. 48.39%, P>0.05). The range of motion of the ADR segment in patients with progressed PO (7.44±4.64 degrees) was significantly lower than that of patients with stable PO grade (12.13±4.42 degrees, P<0.01) at last follow-up., Conclusions: A proportion of HO might in fact be the natural development of preoperative osteophytes, which is unrelated to ADR; the remaining HO might be due to changes in biomechanical environment after surgery, which promotes the grade of osteophytes and affects the segment motion.
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- 2017
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86. Etiology of Adult-onset Stress Fracture in the Lumbar Spine.
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Tezuka F, Sairyo K, Sakai T, and Dezawa A
- Subjects
- Adult, Athletic Injuries complications, Athletic Injuries diagnostic imaging, Female, Fractures, Stress complications, Fractures, Stress diagnostic imaging, Humans, Low Back Pain diagnostic imaging, Low Back Pain etiology, Lumbar Vertebrae diagnostic imaging, Magnetic Resonance Imaging, Male, Retrospective Studies, Spondylolysis complications, Spondylolysis diagnostic imaging, Tomography Scanners, X-Ray Computed, Young Adult, Fractures, Stress etiology, Lumbar Vertebrae pathology, Spondylolysis etiology
- Abstract
Study Design: This study was a case series., Objective: The purpose of this paper was to present a case series of fresh stress fractures (spondylolysis) in the lumbar spines of adult athletes., Summary of Background Data: Lumbar spondylolysis is a stress fracture of the pars interarticularis, which is generally considered a disease of children or adolescence. There is only 1 case series written in English reporting on adult-onset fresh spondylolysis., Methods: Eleven patients aged 20-27 years are included in this case series. A retrospective analysis was made of events that may cause stress fracture such as traumatic episodes or sports activities, spinal level, radiologic findings, stage of spondylolysis, treatment, and prognosis., Results: Among the 11 patients, two had bilateral early-stage spondylolysis, 7 had unilateral early-stage spondylolysis and 2 had unilateral progressive-stage spondylolysis. Three occurred subsequent to a preexisting terminal-stage spondylolysis in the contralateral side, 1 occurred subsequent to a terminal-stage spondylolysis at the adjacent spinal level, and 1 occurred subsequent to a terminal-stage spondylolysis at a distant level. Thirteen pedicles adjacent to the pars interarticularis in the 11 patients showed bone marrow edema-like signal on magnetic resonance imaging. Six spondylolyses were found at L5, 2 each at L3 and L4, and 1 spondylolysis at L2. The 11 patients were divided into 4 groups according to suspected pathogenic mechanism: preexistent spondylolysis in the contralateral side, alteration of the athletic event, apparent traumatic episode, and others. Conservative treatment was prescribed for return to sports in all cases. Although 1 patient retired because of persistent low back pain, the remaining 10 patients returned to competition., Conclusions: Although lumbar spondylolysis is generally recognized to occur in childhood or adolescence, fresh lumbar spondylolysis should be included in the differential diagnosis of adult low back pain when patients are high-level athletes. Conservative treatment should be attempted for adult patients.
- Published
- 2017
- Full Text
- View/download PDF
87. Intraoperative Neural Mobility and Postoperative Neurological Recovery in Anterior Cervical Decompression Surgery: Evaluation With Intraoperative Sonography.
- Author
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Mihara H, Kondo S, Katoh S, Ono M, and Hachiya M
- Subjects
- Adult, Aged, Cervical Vertebrae diagnostic imaging, Female, Humans, Male, Middle Aged, Monitoring, Intraoperative, Severity of Illness Index, Young Adult, Cervical Vertebrae surgery, Decompression, Surgical methods, Intraoperative Neurophysiological Monitoring methods, Recovery of Function physiology, Spinal Cord Compression surgery, Ultrasonography methods
- Abstract
Study Design: A study using intraoperative sonography (IOS) was conducted for evaluating neural mobility in anterior cervical decompression surgery., Objectives: To analyze decompression status and mobility of the spinal cord and the nerve root during anterior cervical decompression and to clarify its relevance to the postoperative neurological recovery., Summary of Background Data: Several papers introduced the usefulness of IOS assessments; however, there have been no reports systematically evaluating the neural mobility in anterior cervical decompression surgery., Methods: Eighty-four consecutive patients with compressive myelopathy who underwent anterior cervical decompression procedures were studied. The decompression status of the spinal cord was evaluated with IOS and classified into 3 grades according to the restoration pattern of the space ventral to the cord. Pulsatile motion of the spinal cord in cranio-caudal direction was named "sliding pulsation" and graded into 3 groups. The nerve root pulsation was also assessed using the IOS short-axis views. This study analyzed whether those neural mobility in anterior cervical decompression surgery had relevance to postoperative neurological recovery, which was assessed by the Japan Orthopaedic Association score., Results: The mean recovery rate of the Japan Orthopaedic Association score was 59.1% in total. According to the decompression status in IOS, 67 patients who acquired space ventral to the spinal cord indicated 64.3% of the recovery rate which was significantly higher than 36.6% of the other patients on an average. As to the sliding pulsation of the cord, 10 patients who failed to show this particular motion indicated significantly lower recovery rate as 36.9%. In addition, 6 patients who did not exhibit nerve root pulsation indicated just 29.3% of recovery rate, and 4 of them failed to show the cord sliding motion., Conclusions: Sonographic evaluation during anterior cervical decompression surgery provided very useful information of neural decompression status that had significant correlation with postoperative neurological recovery.
- Published
- 2016
- Full Text
- View/download PDF
88. The Efficacy of Intraoperative Neurophysiological Monitoring Using Transcranial Electrically Stimulated Muscle-evoked Potentials (TcE-MsEPs) for Predicting Postoperative Segmental Upper Extremity Motor Paresis After Cervical Laminoplasty.
- Author
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Fujiwara Y, Manabe H, Izumi B, Tanaka H, Kawai K, and Tanaka N
- Subjects
- Aged, Deltoid Muscle physiopathology, Female, Humans, Male, Middle Aged, Paresis etiology, Paresis therapy, Prospective Studies, Spinal Cord Diseases complications, Treatment Outcome, Cervical Vertebrae surgery, Evoked Potentials, Motor, Intraoperative Neurophysiological Monitoring, Laminoplasty adverse effects, Paresis diagnosis, Transcranial Direct Current Stimulation
- Abstract
Study Design: Prospective study., Objective: To investigate the efficacy of transcranial electrically stimulated muscle-evoked potentials (TcE-MsEPs) for predicting postoperative segmental upper extremity palsy following cervical laminoplasty., Summary of Background Data: Postoperative segmental upper extremity palsy, especially in the deltoid and biceps (so-called C5 palsy), is the most common complication following cervical laminoplasty. Some papers have reported that postoperative C5 palsy cannot be predicted by TcE-MsEPs, although others have reported that it can be predicted., Methods: This study included 160 consecutive cases that underwent open-door laminoplasty, and TcE-MsEP monitoring was performed in the biceps brachii, triceps brachii, abductor digiti minimi, tibialis anterior, and abductor hallucis. A >50% decrease in the wave amplitude was defined as an alarm point. According to the monitoring alarm, interventions were performed, which include steroid administration, foraminotomies, etc., Results: Postoperative deltoid and biceps palsy occurred in 5 cases. Among the 155 cases without segmental upper extremity palsy, there were no monitoring alarms. Among the 5 deltoid and biceps palsy cases, 3 had significant wave amplitude decreases in the biceps during surgery, and palsy occurred when the patients awoke from anesthesia (acute type). In the other 2 cases in which the palsy occurred 2 days after the operation (delayed type), there were no significant wave decreases. In all of the cases, the palsy was completely resolved within 6 months., Discussion: The majority of C5 palsies have been reported to occur several days after surgery, but some of them have been reported to occur immediately after surgery. Our results demonstrated that TcE-MsEPs can predict the acute type, whereas the delayed type cannot be predicted., Conclusions: A >50% wave amplitude decrease in the biceps is useful to predict acute-type segmental upper extremity palsy. Further examination about the interventions for monitoring alarm will be essential for preventing palsy.
- Published
- 2016
- Full Text
- View/download PDF
89. Microdiscectomy for a Paracentral Lumbar Herniated Disk.
- Author
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Millhouse PW, Schroeder GD, Kurd MF, Kepler CK, Vaccaro AR, and Savage JW
- Subjects
- Humans, Intervertebral Disc Displacement diagnostic imaging, Intervertebral Disc Displacement pathology, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae pathology, Microdissection, Minimally Invasive Surgical Procedures, Postoperative Complications, Radiography, Severity of Illness Index, Intervertebral Disc Displacement surgery, Lumbar Vertebrae surgery
- Abstract
Lumbar disk herniations occur frequently and are often associated with leg pain, weakness, and paresthesias. Fortunately, the natural outcomes of radiculopathy due to a disk herniation are generally favorable, and the vast majority of patients improve with nonoperative care. Surgical intervention is reserved for patients who have significant pain that is refractory to at least 6 weeks of conservative care, patients who have a severe or progressive motor deficit, or patients who have any symptoms of bowel or bladder dysfunction. This paper reviews the preoperative and postoperative considerations, as well as the surgical technique, for a microdiscectomy for a lumbar intervertebral disk herniation.
- Published
- 2016
- Full Text
- View/download PDF
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