1. Musculoskeletal disorders in hemodialysis patients: different disease clustering according to age and dialysis vintage
- Author
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Nathalie El-Khoury, Dania Chelala, Sandrine Hage, Nelly Ziade, Hiba Azar, and Valérie Hage
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,medicine.medical_treatment ,Population ,Chondrocalcinosis ,Osteoarthritis ,Disease ,Disease cluster ,Fractures, Bone ,03 medical and health sciences ,0302 clinical medicine ,Rheumatology ,Musculoskeletal Pain ,Renal Dialysis ,Internal medicine ,Prevalence ,medicine ,Cluster Analysis ,Humans ,030212 general & internal medicine ,Lebanon ,education ,Carpal tunnel syndrome ,Serum Albumin ,Dialysis ,Aged ,Aged, 80 and over ,Chronic Kidney Disease-Mineral and Bone Disorder ,030203 arthritis & rheumatology ,education.field_of_study ,Duration of Therapy ,business.industry ,Phosphorus ,General Medicine ,Middle Aged ,Alkaline Phosphatase ,medicine.disease ,Carpal Tunnel Syndrome ,Parathyroid Hormone ,Tendinopathy ,Kidney Failure, Chronic ,Calcium ,Female ,Hemodialysis ,business - Abstract
Musculoskeletal disorders remain a major problem in hemodialysis patients. The aim of the study was to estimate the prevalence of musculoskeletal manifestations in hemodialysis patients and identify disease cluster profiles. We performed a cross-sectional study including all adult patients in the hemodialysis unit at Hotel-Dieu de France Hospital. We collected demographic characteristics, musculoskeletal symptoms, biologic parameters, and treatments. Musculoskeletal disorders were classified by a rheumatologist into predefined diagnostic categories. Prevalence was presented, and a cluster analysis was performed. Eighty-nine patients were included, mean age was 67.5 ± 12 years, and 43.8% were female. Dialysis vintage was 5.7 ± 5.37 years. Musculoskeletal symptoms were reported by 76.4% of the patients. Pain was the most frequent symptom (44.9%). The main diagnoses were osteoarthritis (53.9%) and fracture (27%). Musculoskeletal symptoms and disorders were significantly associated with dialysis vintage and age. Cluster analysis identified three patient profiles: younger with low calcium levels, younger but long dialysis vintage with osteoarthritis and carpal tunnel syndrome, and older with long dialysis vintage and fractures. The prevalence of musculoskeletal manifestations is high in the hemodialysis population and increases with dialysis vintage. Musculoskeletal disorders cluster according to age and dialysis vintage. Key Points• Musculoskeletal symptoms are highly prevalent among hemodialysis patients (76.4%).• All musculoskeletal disorders are associated with dialysis vintage and age.• Three clusters are identified among hemodialysis patients: young with low calcium levels, young but long dialysis vintage with osteoarthritis and carpal tunnel syndrome and old with long dialysis vintage with fractures.
- Published
- 2019
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