1. Visualization of Risk Factors and Predictive Models for Early Death of Neonatal Gastric Perforation.
- Author
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Mengying, Cui, Pengfei, Chen, Jinfeng, Hou, Yi, Wang, Wei, Liu, and Zhenhua, Guo
- Subjects
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RISK assessment , *PREDICTION models , *PLATELET count , *ABDOMINAL surgery , *LOGISTIC regression analysis , *HYPERKALEMIA , *POTASSIUM , *PERINATAL death , *RETROSPECTIVE studies , *BICARBONATE ions , *DESCRIPTIVE statistics , *PEDIATRICS , *ODDS ratio , *ARTERIAL pressure , *GASTRIC diseases , *INTENSIVE care units , *VOMITING , *CONFIDENCE intervals , *ACIDOSIS , *HYPOXEMIA , *SENSITIVITY & specificity (Statistics) , *CHILDREN - Abstract
A retrospective analysis was performed from May 2003 to October 2021 at our hospital. One hundred and eleven neonates diagnosed with gastric perforation were categorized into non-survivor and survivor groups based on prognosis. The mortality rate was 23.42%. Logistic regression was used to analyze the factors influencing the early neonatal death. The non-survivor groups showed more abdominal distension, vomiting, hypoxia, acidosis, hyperkalemia, and coagulation abnormalities. Serum potassium concentration (odds ratio [OR] 2.148, P =.043) was an independent risk factor; however, arterial partial pressure of oxygen (OR 0.977, P =.024), bicarbonate (OR 0.779, P =.023), and platelet count (OR 0.986, P =.014) had protective effects on neonatal death. Based on this, a visualized nomogram prediction model was constructed, patients who had a nomogram score of more than 163.787 was considered to have high risks of mortality, the area under the curve of this was up to 0.828 (95% confidence interval [0.733, 0.923]), the sensitivity was 80.0%, and the specificity was 76.9%. [ABSTRACT FROM AUTHOR]
- Published
- 2024
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