27 results on '"bell’s palsy"'
Search Results
2. Electromyography in the prognostication of recovery in patients with acute peripheral facial nerve palsy: A systematic review.
- Author
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Petrides, George Andrew, Hayler, Raymond, Lee, Jennifer W., Jankelowitz, Stacey, and Low, Tsu‐Hui
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FACIAL nerve , *BELL'S palsy , *PERIPHERAL nervous system , *ELECTROMYOGRAPHY , *PROGNOSIS , *FACIAL paralysis , *NEEDLESTICK injuries - Abstract
Objectives: Needle electromyography (EMG) may be used to characterise the severity of the injury in acute peripheral facial nerve palsy (FNP) to predict recovery and guide management, but its prognostic value and clinical utility remain controversial. The aim of this systematic review was to evaluate the role of EMG to prognosticate the recovery of facial motor function in patients with acute peripheral FNP. Design: A comprehensive search strategy was applied in PubMed, Embase, and Web of Science based on Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. The main outcome measure was the accuracy of EMG in predicting long‐term facial function at least 6 months following symptom onset. Results: Eleven studies were included comprising 3837 participants, with 91.6% of these diagnosed with Bell's palsy (BP). In BP patients, the positive predictive value and negative predictive value for a good outcome based on EMG findings ranged from 82.1% to 100% and 66.7% to 80.5%, respectively, with two out of three studies finding that EMG remained a significant predictor of the outcome on multivariate analysis. Three studies addressed the role of EMG in non‐idiopathic FNP with two of these studies supporting EMG to predict prognosis. Conclusions: EMG is a useful tool to gain insight into the likely outcome to guide management decisions and counsel patients on their expectations, particularly in BP. However, given inconsistencies in its application and lack of evidence around non‐idiopathic FNP, it should not currently be relied on to predict recovery. Ultimately, its prognostic value and widespread adoption are dependent on the implementation of a clear and standardised protocol in future high‐quality studies and routine clinical settings. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
3. Bell's palsy and pregnancy: Incidence, comorbidities and complications. A meta‐analysis and systematic review of the literature.
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Carmel Neiderman, Narin N., Netanyahu, Yael, Ungar, Omer J., Handzel, Ophir, Masarwy, Razan, Abu‐Eta, Rani, Reicher, Lee, and Oron, Yahav
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BELL'S palsy , *PERIPARTUM cardiomyopathy , *PREGNANCY complications , *GESTATIONAL diabetes , *PREGNANCY , *PREGNANT women - Abstract
Objectives: Data on the association between Bell's palsy (BP) and pregnancy is scarce and there is an ongoing debate regarding the association of BP and pregnancy. Main Outcome Measures: We aimed to investigate the prevalence of BP among pregnant patients and determine the frequency of pregnant women in BP cohorts and vice versa, assess which term of the pregnancy and peripartum bears a higher risk for BP occurrence, and determine the prevalence of maternal comorbidities associated with BP during pregnancy. Design: Meta analysis. Settings: Screening standard articles and extracting data from Ovid MEDLINE (1960–2021), Embase (1960–2021), and Web of Science (1960–2021). All study types were included except for case reports. Measures: Data were pooled by means of both fixed and random‐effects models. Results: The search strategy identified 147 records. Twenty‐five of the studies that met our inclusion criteria described 809 pregnant patients with BP in a total of 11,813 BP patients and they were included in the meta‐analysis. The incidence of BP among the pregnant patients was 0.05%; The incidence of pregnant patients among all BP patients was 6.62%. Most of the BP occurrences were during the third trimester (68.82%). The pooled incidence of gestational diabetes mellitus; hypertension; pre‐eclampsia/eclampsia and fetal complications among the pregnant patients with BP was 6.3%, 13.97%, 9.54%, and 6.74%, respectively. Conclusions: This meta‐analysis revealed a low incidence of BP during pregnancy. A Higher proportion occurred during the third trimester. The association of BP and pregnancy warrants further exploration. [ABSTRACT FROM AUTHOR]
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- 2023
- Full Text
- View/download PDF
4. Facial and hearing outcomes in transmastoid nerve decompression for Bell's palsy, with preservation of the ossicular chain.
- Author
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Inagaki, Akira, Takahashi, Mariko, and Murakami, Shingo
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BELL'S palsy , *EAR ossicles , *FACIAL nerve , *PAROTIDECTOMY , *MASTOIDECTOMY , *NEURODEGENERATION , *NERVES - Abstract
Objectives: Facial nerve decompression is a salvage treatment for Bell's palsy patients for whom a poor prognosis is anticipated with standard medical treatment. The transmastoid approach is a frequently performed approach, but it remains unknown if this surgery is effective when the ossicular chain is preserved. This study aimed to determine the efficacy of facial nerve decompression using the transmastoid approach in Bell's palsy. Design, setting and participants: This retrospective study included patients who had undergone transmastoid facial nerve decompression with ossicular chain preservation and patients who met the criteria for surgery, but received only medical treatment between January 2007 and May 2019, at a single centre. Main outcome measures: Attainment of House‐Brackmann grade I at 12 months after onset of facial palsy. Results: The recovery rate to House‐Brackmann grade I in the decompression group in the early phase (≤18 days after onset) was higher than that of the medical treatment group, although the difference was not significant (70% vs 47%, P =.160). However, within this early surgery group, a subgroup of cases with ≥95% facial nerve degeneration demonstrated a significant improvement in recovery rate (73% vs 30%, P =.018). Among surgeries performed in the late phase (≥19 days), only a subgroup with ≥95% facial nerve degeneration was available for analysis, and the difference in recovery rate was not significant compared with medical treatment alone (26% vs 30%, P = 1.00). Post‐surgical hearing evaluation demonstrated that average hearing deterioration was 1.3 dB which was non‐significant, suggesting this procedure does not cause hearing loss. Conclusions: Transmastoid facial nerve decompression with ossicular chain preservation in the early phase after symptom‐onset is an effective salvage treatment for severe Bell's palsy with ≥95% facial nerve degeneration. [ABSTRACT FROM AUTHOR]
- Published
- 2021
- Full Text
- View/download PDF
5. Prognostic factors for the outcome of Bells' palsy: A cohort register‐based study.
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Urban, Elisabeth, Volk, Gerd Fabian, Geißler, Katharina, Thielker, Jovanna, Dittberner, Andreas, Klingner, Carsten, Witte, Otto W., and Guntinas‐Lichius, Orlando
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BELL'S palsy , *PARALYSIS , *COHORT analysis , *UNIVERSITY hospitals - Abstract
Objectives: There is a lack of data on patients' and diagnostic factors for prognostication of complete recovery in patients with Bell's palsy. Design and setting: Cohort register‐based study of 368 patients with Bell's palsy and uniform diagnostics and standardised treatment in a university hospital from 2007 to 2017 (49% female, median age: 51 years). Main outcome measures: Clinical data, facial grading, electrodiagnostics, motor function tests, non‐motor function tests and onset of prednisolone therapy were assessed for their impact on the probability of complete recovery using univariable and multivariable statistics. Results: Median onset of treatment was 1.5 days. 46% of patients had a House‐Brackmann scale at baseline of ≥ III. The median recovery time was 2.6 months (95% confidence interval [CI] = 2.1‐3.0). 54.9% achieved a complete recovery. If prednisolone therapy started later than 96 hours after onset, the recovery rate decreased significantly. Beyond less severe palsy, no abnormal electroneurography side difference, no pathological spontaneous activity in electromyography and normal stapedius reflex testing were the most powerful tool for prognostication of recovery after Bell's palsy. Conclusion: Beyond severity of the palsy, facial electrodiagnostics and stapedius reflex testing are the most powerful tool for prognostication of recovery time after Bell's palsy. Prednisolone therapy should have started at best within a time window of 96 hours after onset to reach the highest probability of complete recovery. [ABSTRACT FROM AUTHOR]
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- 2020
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6. CT and clinical prognostic factors in Bell's palsy: A study of 56 cases.
- Author
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Hervochon, Rémi, Madelain, Vincent, Seiller, Ian, Lahlou, Ghizlene, Nguyen, Yann, and Tankéré, Frédéric
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BELL'S palsy , *PICTURE archiving & communication systems - Abstract
The aim of this study was to carry out a radio-clinical assessment in order to identify CT and clinical prognostic criteria in Bell's palsy. For all patients admitted for Bell's palsy, we searched our hospital's Picture Archiving and Communication System (PACS) for those patients who had a petrous CT scan. 1 Abbreviations: BMI, Body Mass Index; BP, Bell's palsy. 1 Hervochon R, Seiller I, Trunet S, Nguyen Y, Tankéré F. Morphometric analysis of CT scans of the facial canal in Bell's palsy: a study of 51 patients. [Extracted from the article]
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- 2019
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7. Morphometric analysis of CT scans of the facial canal in Bell's palsy: A study of 51 patients.
- Author
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Hervochon, Rémi, Seiller, Ian, Trunet, Stéphanie, Nguyen, Yann, and Tankéré, Frédéric
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BELL'S palsy - Abstract
The article discusses a study to compare the anatomical criteria ofthe facial canal on petrous computed tomography (CT) scans from Bell's palsy (BP) patients and controls. Topics discussed include the measurement of the size of the bony canal of the facial nerve on CT scans, several aetiological factors causing BP such as viral infections, autoimmune reactions or ischaemic neuropathy of the vasa nervorum, and angles of the first and second genu.
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- 2019
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8. Recurrent Bell's palsy.
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Dong, Sung Hwa, Jung, Ah Ra, Jung, Junyang, Jung, Su Young, Byun, Jae Yong, Park, Moon Suh, Kim, Sang Hoon, and Yeo, Seung Geun
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BELL'S palsy , *META-analysis , *DISEASE relapse , *SYMPTOMS , *DISEASE incidence , *PROGNOSIS - Abstract
Objective: Although recurrent facial palsy was first reported in 1871, the aetiology, definitions, classifications, pathogenesis, treatment options and prognosis have not been clearly determined. There have been no systematic reviews and meta‐analyses of recurrent Bell's palsy. The purpose of this study was to evaluate the clinical manifestations of recurrent Bell's palsy through a systematic review and meta‐analysis. Design: The SCOPUS, PubMed, Cochrane Library and EBSCO databases were searched through 1 May 2018, using the search terms "recurrent Bell's palsy" and "recurrent facial palsy," for studies involving patients with recurrent Bell's palsy. Reference lists of eligible studies were also reviewed. Results: A search of titles and abstracts in these four databases identified 222 studies; of these, 27 studies, involving 1041 patients from 13 countries, were analysed. The mean percentage of patients who experienced recurrence of Bell's palsy ranged from 0.8% to 19.4%. Five studies that included 191 patients were included in the meta‐analysis. Conclusions: Among patients previously affected by Bell's palsy, the mean incidence of recurrent Bell's palsy was 6.5%. Sidedness of recurrent disease, relative to the side of the original disease, had no effect on patient prognosis. Of all patients with Bell's palsy, 66.0% recovered completely, with the recovery rate lower in patients with recurrent than with primary Bell's palsy. [ABSTRACT FROM AUTHOR]
- Published
- 2019
- Full Text
- View/download PDF
9. Inpatient treatment of patients with acute idiopathic peripheral facial palsy: A population-based healthcare research study.
- Author
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Plumbaum, K., Volk, G.F., Boeger, D., Buentzel, J., Esser, D., Steinbrecher, A., Hoffmann, K., Jecker, P., Mueller, A., Radtke, G., Witte, O.W., and Guntinas‐Lichius, O.
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TREATMENT of facial paralysis , *MEDICAL care research , *HEALTH outcome assessment , *PREDNISOLONE , *HORMONE therapy , *ADRENOCORTICAL hormones , *OTOLARYNGOLOGY - Abstract
Objectives To determine the inpatient management for patients with acute idiopathic facial palsy ( IFP) in Thuringia, Germany. Design Population-based study. Setting All inpatients with IFP in all hospitals with departments of otolaryngology and neurology in 2012, in the German federal state, Thuringia. Main outcome measures Patients' characteristics and treatment were compared between departments, and the probability of recovery was tested. Results A total of 291 patients were mainly treated in departments of otolaryngology (55%) and neurology (36%). Corticosteroid treatment was the predominant therapy (84.5%). The probability to receive a facial nerve grading (odds ratio [ OR=12.939; 95% confidence interval [ CI]=3.599 to 46.516), gustatory testing ( OR=6.878; CI=1.064 to 44.474) and audiometry ( OR=32.505; CI=1.485 to 711.257) was significantly higher in otolaryngology departments, but lower for cranial CT ( OR=0.192; CI=0.061 to 0.602), cerebrospinal fluid examination ( OR=0.024; CI=0.006 to 0.102). A total of 131 patients (45%) showed a recovery to House-Brackmann grade≤ II. A pathological stapedial reflex test (Hazard ratio [ HR]=0.416; CI=0.180 to 0.959) was the only independent diagnostic predictor of worse outcome. Prednisolone dose >500 mg ( HR=0.579; CI 0.400 to 0.838) and no adjuvant physiotherapy ( HR=0.568; CI=0.407 to 0.794) were treatment-related predictors of worse outcome. Conclusions Inpatient treatment of IFP seems to be highly variable in daily practice, partly depending on the treating discipline and despite the availability of evidence-based guidelines. The population-based recovery rate was worse than reported in clinical trials. [ABSTRACT FROM AUTHOR]
- Published
- 2017
- Full Text
- View/download PDF
10. Facial and hearing outcomes in transmastoid nerve decompression for Bell's palsy, with preservation of the ossicular chain
- Author
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Mariko Takahashi, Akira Inagaki, and Shingo Murakami
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Decompression ,Hearing loss ,Degeneration (medical) ,Mastoid ,03 medical and health sciences ,0302 clinical medicine ,Bell's palsy ,medicine ,Bell Palsy ,Humans ,steroid therapy ,030223 otorhinolaryngology ,Ear Ossicles ,Retrospective Studies ,Salvage Therapy ,Ossicular chain ,Palsy ,business.industry ,Hearing Tests ,Retrospective cohort study ,Original Articles ,ossicular chain preservation ,Recovery of Function ,Middle Aged ,medicine.disease ,Decompression, Surgical ,Prognosis ,Facial nerve ,Surgery ,facial nerve decompression ,Otorhinolaryngology ,030220 oncology & carcinogenesis ,Original Article ,Female ,medicine.symptom ,transmastoid approach ,business - Abstract
Objectives Facial nerve decompression is a salvage treatment for Bell's palsy patients for whom a poor prognosis is anticipated with standard medical treatment. The transmastoid approach is a frequently performed approach, but it remains unknown if this surgery is effective when the ossicular chain is preserved. This study aimed to determine the efficacy of facial nerve decompression using the transmastoid approach in Bell's palsy. Design, setting and participants This retrospective study included patients who had undergone transmastoid facial nerve decompression with ossicular chain preservation and patients who met the criteria for surgery, but received only medical treatment between January 2007 and May 2019, at a single centre. Main outcome measures Attainment of House-Brackmann grade I at 12 months after onset of facial palsy. Results The recovery rate to House-Brackmann grade I in the decompression group in the early phase (≤18 days after onset) was higher than that of the medical treatment group, although the difference was not significant (70% vs 47%, P = .160). However, within this early surgery group, a subgroup of cases with ≥95% facial nerve degeneration demonstrated a significant improvement in recovery rate (73% vs 30%, P = .018). Among surgeries performed in the late phase (≥19 days), only a subgroup with ≥95% facial nerve degeneration was available for analysis, and the difference in recovery rate was not significant compared with medical treatment alone (26% vs 30%, P = 1.00). Post-surgical hearing evaluation demonstrated that average hearing deterioration was 1.3 dB which was non-significant, suggesting this procedure does not cause hearing loss. Conclusions Transmastoid facial nerve decompression with ossicular chain preservation in the early phase after symptom-onset is an effective salvage treatment for severe Bell's palsy with ≥95% facial nerve degeneration.
- Published
- 2020
11. CT and clinical prognostic factors in Bell's palsy: A study of 56 cases
- Author
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Yann Nguyen, F. Tankéré, Ghizlene Lahlou, Rémi Hervochon, Vincent Madelain, and Ian Seiller
- Subjects
Pediatrics ,medicine.medical_specialty ,business.industry ,Facial Paralysis ,Prognosis ,medicine.disease ,Imaging, Three-Dimensional ,ROC Curve ,Otorhinolaryngology ,Multidetector Computed Tomography ,Bell's palsy ,Bell Palsy ,medicine ,Humans ,business ,Follow-Up Studies ,Petrous Bone ,Retrospective Studies - Published
- 2019
12. Morphometric analysis of CT scans of the facial canal in Bell’s palsy: A study of 51 patients
- Author
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Yann Nguyen, F. Tankéré, Rémi Hervochon, Stéphanie Trunet, and Ian Seiller
- Subjects
Male ,Orthodontics ,business.industry ,MEDLINE ,Contrast Media ,medicine.disease ,Magnetic Resonance Imaging ,Imaging, Three-Dimensional ,Facial canal ,medicine.anatomical_structure ,Otorhinolaryngology ,Morphometric analysis ,Bell's palsy ,Bell Palsy ,medicine ,Humans ,Radiographic Image Interpretation, Computer-Assisted ,Female ,Tomography, X-Ray Computed ,business ,Retrospective Studies - Published
- 2019
13. Inpatient treatment of patients with acute idiopathic peripheral facial palsy: A population-based healthcare research study
- Author
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Dirk Esser, Katharina Plumbaum, Andreas Steinbrecher, Katrin Hoffmann, Andreas Mueller, Gerald Radtke, Jens Buentzel, Gerd Fabian Volk, Daniel Boeger, Orlando Guntinas-Lichius, Otto W. Witte, and Peter Jecker
- Subjects
Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Population ,Hospital Departments ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Germany ,Bell's palsy ,Bell Palsy ,medicine ,Humans ,Child ,030223 otorhinolaryngology ,education ,Aged ,Retrospective Studies ,Aged, 80 and over ,education.field_of_study ,business.industry ,Hazard ratio ,Infant ,Recovery of Function ,Odds ratio ,Middle Aged ,medicine.disease ,Confidence interval ,Hospitalization ,Clinical trial ,Outcome and Process Assessment, Health Care ,Otorhinolaryngology ,Child, Preschool ,Acute Disease ,Prednisolone ,Female ,Health Services Research ,business ,030217 neurology & neurosurgery ,medicine.drug - Abstract
Objectives To determine the inpatient management for patients with acute idiopathic facial palsy (IFP) in Thuringia, Germany. Design Population-based study. Setting All inpatients with IFP in all hospitals with departments of otolaryngology and neurology in 2012 in the German federal state Thuringia. Main outcome measures Patients’ characteristics and treatment were compared between departments, and the probability of recovery was tested. Results 291 patients were mainly treated in departments of otolaryngology (55%) and neurology (36%). Corticosteroid treatment was the predominant therapy (84.5%). The probability to receive a facial nerve grading (Odds ratio [OR] =12.939; 95% confidence interval [CI] = 3.599 to 46.516), gustatory testing (OR = 6.878; CI =1.064 to 44.474), and audiometry (OR = 32.505; CI = 1.485 to 711.257) was significantly higher in otolaryngology departments, but lower for cranial CT (OR = 0.192; CI = 0.061 to 0.602), CSF examination (OR = 0.024; CI = 0.006 to 0.102). 131 patients (45%) showed a recovery to House-Brackmann grade ≤II. A pathological stapedial reflex test (Hazard ratio [HR] = 0.416; CI = 0.180 to 0.959) was the only independent diagnostic predictor of worse outcome. Prednisolone dose >500 mg (HR = 0.579; CI 0.400 to 0.838), and no adjuvant physiotherapy (HR = 0.568; CI = 0.407 to 0.794) were treatment-related predictors of worse outcome. Conclusions Inpatient treatment of IFP seems to be highly variable in daily practice, partly depending on the treating discipline, and despite the availability of evidence-based guidelines. The population-based recovery rate was worse than reported in clinical trials. This article is protected by copyright. All rights reserved.
- Published
- 2017
14. Synkinesis in Bell's palsy in a randomised controlled trial
- Author
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Malou Hultcrantz, Sara Enghag, Elin Marsk, David Jensson, Lars Jonsson, Thomas Berg, Andres Rodriguez-Lorenzo, Nermin Hadziosmanovic, and Nina Bylund
- Subjects
Adult ,Male ,medicine.medical_specialty ,Time Factors ,Adolescent ,Synkinesis ,Prednisolone ,Acyclovir ,macromolecular substances ,030230 surgery ,Antiviral Agents ,law.invention ,Young Adult ,03 medical and health sciences ,0302 clinical medicine ,Double-Blind Method ,Randomized controlled trial ,law ,Bell's palsy ,Bell Palsy ,Humans ,Medicine ,030223 otorhinolaryngology ,Glucocorticoids ,Aged ,Palsy ,Dose-Response Relationship, Drug ,business.industry ,Valine ,Middle Aged ,medicine.disease ,stomatognathic diseases ,Treatment Outcome ,Otorhinolaryngology ,Valacyclovir ,Physical therapy ,Drug Therapy, Combination ,Female ,business ,human activities ,Follow-Up Studies - Abstract
To study the development of synkinesis in Bell's palsy. Frequency, severity, gender aspects and predictors were analysed.Data from the randomised controlled Scandinavian Bell's palsy trial including 829 patients.Frequency and severity of synkinesis at 12 months were the main outcome measures. Mean Sunnybrook synkinesis scores, voluntary movement scores and composite scores between 6 and 12 months were compared.In 743 patients with a 12-month follow-up, synkinesis frequency was 21.3%. There was no gender difference. Synkinesis was moderate to severe in 6.6% of patients. Those with synkinesis at 6 months had a synkinesis score of 4.1 (±2.8 sd), which increased to 4.7 (±3.2) (P = 0.047) at 12 months (n = 93). Sunnybrook composite score at 1 month was the best predictor for synkinesis development with receiver operating characteristics and area under the curve (AUC) 0.87. Risk for synkinesis increased with a lower Sunnybrook composite score. Furthermore, at 1 month, symmetry of voluntary movement had higher predictive value for synkinesis than resting symmetry with AUC 0.87 and 0.77, respectively. Gentle eye closure and open-mouth smile were the only independent significant predictive items (AUC 0.86).Moderate-to-severe synkinesis was present in 6.6% of patients. The mean synkinesis score increased between 6 and 12 months, and outcome should therefore be evaluated after at least 12 months. Sunnybrook composite score and symmetry of voluntary movement at 1 month were good predictors for synkinesis.
- Published
- 2016
15. Bell’s palsy - the effect of prednisolone and/or valaciclovir versus placebo in relation to baseline severity in a randomised controlled trial
- Author
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Mats Engström, Lars Jonsson, Sara Axelsson, Anna Stjernquist-Desatnik, Thomas Berg, and Mervi Kanerva
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medicine.medical_specialty ,Palsy ,business.industry ,medicine.disease ,Placebo ,law.invention ,Valaciclovir ,Surgery ,Otorhinolaryngology ,Randomized controlled trial ,law ,Anesthesia ,Bell's palsy ,Severity of illness ,medicine ,Prednisolone ,Prospective cohort study ,business ,medicine.drug - Abstract
Objectives: To evaluate the treatment effect of prednisolone and/or valaciclovir in Bell's palsy patients with different baseline severity of palsy. Design: Patient data were collected from the Scandinavian Bell's Palsy Study, a prospective, randomized, double-blind, placebo-controlled, multi-centre trial. Setting: Sixteen otorhinolaryngological centres in Sweden and one in Finland. Participants: Altogether 829 patients aged 18-75 years were treated within 72 hours of palsy onset. Patients were randomly assigned to treatment with prednisolone plus placebo (n=210), valaciclovir plus placebo (n=207), prednisolone plus valaciclovir (n=206), placebo plus placebo (n=206). Follow-up was 12 months. Main outcome measures: Facial function was assessed using the Sunnybrook grading scale at baseline and at 12 months. Complete recovery was defined as Sunnybrook score = 100. Results: All patients, regardless of baseline severity, showed significantly higher complete recovery rates if treated with prednisolone compared with no prednisolone. In patients with severe palsy, recovery at 12 months was 51% with prednisolone treatment versus 31% without prednisolone (P=0.02). Corresponding results were 68% versus 51% (P=0.004) for moderate, and 83% versus 73% (P=0.02) for mild palsy. In patient groups with moderate and mild palsy at baseline, significantly fewer prednisolone-treated patients had synkinesis at 12 months (P=0.04 and P
- Published
- 2012
16. Bell’s palsy: a review of three systematic reviews of steroid and anti-viral therapy
- Author
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G.G. Browning
- Subjects
medicine.medical_specialty ,Pediatrics ,business.industry ,Treatment outcome ,Anti-Inflammatory Agents ,Alternative medicine ,MEDLINE ,Acyclovir ,Valine ,medicine.disease ,Antiviral Agents ,Treatment Outcome ,Systematic review ,Otorhinolaryngology ,Valacyclovir ,Bell's palsy ,Bell Palsy ,medicine ,Humans ,Prednisone ,Viral therapy ,business ,Systematic Reviews as Topic - Published
- 2010
17. Salivary flow rate and acute-phase proteins in Bell's palsy
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A. V. Nieuw Amerongen, L. Abraham-Inpijn, and I. Keur
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Adult ,Male ,Saliva ,Pathology ,medicine.medical_specialty ,Sialography ,Facial Paralysis ,Physiology ,Functional Laterality ,fluids and secretions ,stomatognathic system ,Bell's palsy ,medicine ,Humans ,Parotid Gland ,alpha-Macroglobulins ,Salivary Proteins and Peptides ,Aged ,Palsy ,Haptoglobins ,biology ,medicine.diagnostic_test ,business.industry ,Haptoglobin ,Acute-phase protein ,Ceruloplasmin ,Middle Aged ,medicine.disease ,Parotid gland ,stomatognathic diseases ,medicine.anatomical_structure ,Otorhinolaryngology ,biology.protein ,Female ,business ,Acute-Phase Proteins - Abstract
The flow rate of extra-parotid and parotid saliva was compared in patients with Bell's palsy and in healthy volunteers. Samples were analysed for the concentration of total protein and seven acute-phase proteins. There was no difference between younger and older patients with regard to oral status, salivary flow rate, total protein or acute-phase proteins, in either extra-parotid or parotid saliva. No significant difference in flow rate for both extra-parotid and parotid saliva was found in the Bell's palsy patients in comparison with the controls. In the patients the salivary flow rate from the parotid gland on the paralysed side was slightly lower than on the healthy side, but not to a significant extent. The quantity of total protein was lower in the extra-parotid saliva in the patient group; there were no differences between the two groups with regard to parotid saliva. We were able to demonstrate small amounts of various acute-phase proteins in the control group. In the patients we found higher quantities per minute of acute-phase proteins in both extra-parotid saliva and parotid saliva than in the controls. In extra-parotid saliva there were significant differences in haptoglobulin, alpha 2-macroglobulin, C3-complement factor and ceruloplasmin; in parotid saliva the differences in haptoglobulin and ceruloplasmin were significant. However, there was a large inter individual variation in both groups studied. In the patient group no significant difference in the secretion of acute-phase proteins from the parotid gland could be demonstrated between the paralysed side and the healthy side.(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1994
18. Valaciclovir in combination with prednisolone for Bell's palsy
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Ken. McAlister, J. Alexander De Ru, T.K. Blackburn, Edwin L. Van der Veen, Peter Brennan, and Cara R. Featherstone
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Male ,Pediatrics ,medicine.medical_specialty ,business.industry ,Prednisolone ,Acyclovir ,Valine ,medicine.disease ,Antiviral Agents ,Valaciclovir ,Otorhinolaryngology ,Bell's palsy ,Bell Palsy ,Humans ,Medicine ,Female ,business ,Glucocorticoids ,medicine.drug - Published
- 2014
19. The prognostic value of facial electroneurography in Bell's palsy
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C. Maynard, J. A. M. Murray, R. Barr-Hamilton, I. M. Smith, R. E. Mountain, and M.W.J. Armstrong
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Male ,medicine.medical_specialty ,Electrodiagnosis ,Facial Paralysis ,Action Potentials ,Predictive Value of Tests ,Electroneuronography ,Bell's palsy ,medicine ,Humans ,Retrospective Studies ,Palsy ,medicine.diagnostic_test ,business.industry ,Middle Aged ,Prognosis ,medicine.disease ,Facial nerve ,Facial paralysis ,Surgery ,Facial Nerve ,Otorhinolaryngology ,Predictive value of tests ,Nerve Degeneration ,Female ,Presentation (obstetrics) ,business - Abstract
Twenty six patients with Bell's palsy were studied at presentation using electroneurography. Ninety-four per cent of those who recovered completely could have been predicted by ENoG within 10 days of onset. Of the 18 patients who recovered completely, 13 had a total palsy at presentation.
- Published
- 1994
20. Re: Prognostic value of electroneurography in Bell’s palsy and Ramsay-Hunt’s syndrome
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M.‐W. Kim and E.‐H. Kim
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Pediatrics ,medicine.medical_specialty ,S syndrome ,Otorhinolaryngology ,business.industry ,Electroneuronography ,Bell's palsy ,Medicine ,Ramsay hunt ,business ,medicine.disease ,Value (mathematics) - Published
- 2011
21. Two Bell’s palsy studies that are complimentary
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G.G. Browning
- Subjects
medicine.medical_specialty ,Physical medicine and rehabilitation ,Otorhinolaryngology ,business.industry ,Bell's palsy ,medicine ,medicine.disease ,business - Published
- 2009
22. Prednisolone and valaciclovir in Bell’s palsy: a randomized, double-blind, placebo-controlled, multicentre trial
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Lars Jonsson, Thomas Berg, Mervi Kanerva, Per Hanner, Sara Axelsson, Malou Hultcrantz, Anne Pitkäranta, Anna Stjernquist-Desatnik, and Mats Engström
- Subjects
Double blind ,medicine.medical_specialty ,Otorhinolaryngology ,business.industry ,Bell's palsy ,medicine ,Prednisolone ,medicine.disease ,Placebo ,business ,Valaciclovir ,medicine.drug ,Surgery - Published
- 2009
23. Prednisolone improves complete recovery to 94% in Bell’s palsy
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G.G. Browning
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medicine.medical_specialty ,Otorhinolaryngology ,business.industry ,Bell's palsy ,Physical therapy ,Prednisolone ,Medicine ,business ,medicine.disease ,medicine.drug - Published
- 2007
24. Early Treatment with Prednisolone or Acyclovir in Bell’s Palsy
- Author
-
Luke Vale, Brian McKinstry, Fergus Daly, Ken Stewart, Peter T. Donnan, Blair H. Smith, Janet E. Ciarkson, Frank Sullivan, Richard Davenport, Anne McAteer, Jillian Morrison, Victoria Hammersley, Iain R. C. Swan, and Sima Hayavi
- Subjects
Pediatrics ,medicine.medical_specialty ,Otorhinolaryngology ,business.industry ,Bell's palsy ,medicine ,Prednisolone ,business ,medicine.disease ,medicine.drug - Published
- 2007
25. Bell's palsy ? which factors determine final recovery?
- Author
-
Roger E. Cull and Ian M. Smith
- Subjects
Pediatrics ,medicine.medical_specialty ,business.industry ,Facial Paralysis ,Facial Muscles ,Prognosis ,medicine.disease ,Axons ,Nerve Regeneration ,Facial Expression ,Facial Nerve ,Treatment Outcome ,Otorhinolaryngology ,Nerve Degeneration ,Bell's palsy ,medicine ,Humans ,business - Published
- 1994
26. Bell's palsy: prognostic accuracy of case history, sialometry and taste impairment
- Author
-
Tom Ekstrand
- Subjects
Adult ,Male ,Pediatrics ,medicine.medical_specialty ,Adolescent ,Facial Paralysis ,Submandibular Gland ,Pain ,Audiology ,Xerostomia ,Diabetes Complications ,Taste Disorders ,Bell's palsy ,Humans ,Medicine ,Child ,Ear Diseases ,Medical History Taking ,Physical Examination ,Aged ,Palsy ,business.industry ,Electrodiagnosis ,Infant ,Middle Aged ,Prognosis ,medicine.disease ,Otorhinolaryngology ,Child, Preschool ,Taste ,Female ,Chorda Tympani Nerve ,Seasons ,Salivation ,business - Abstract
A prognostic test in cases of Bell's palsy must be accurate and applicable early in the course of the disease. The case history is examined in 239 patients with Bell's palsy. The prognostic value of the case history, taste impairment and sialometry is investigated in a series of untreated patients who were followed up for 12 months. Sialometry is advocated as a reliable prognostic indicator in the individual patient if a strong stimulant is used. None of the other examined parameters discrimates between good and poor outcome with reasonable accuracy. A follow-up time of 12 months is advocated in determining the ultimate outcome of a Bell's palsy.
- Published
- 1979
27. Bell's palsy: factors affecting the prognosis in 200 patients with reference to hypertension and diabetes mellitus
- Author
-
L. Abraham-Inpijn, A. A. M. Hart, and J. Oosting
- Subjects
Male ,Pediatrics ,medicine.medical_specialty ,Palsy ,business.industry ,Facial Paralysis ,Prognosis ,medicine.disease ,Synaptic Transmission ,Clinical study ,Facial Nerve ,Clinical prognosis ,Diabetic Neuropathies ,Otorhinolaryngology ,Diabetes mellitus ,Hypertension ,Bell's palsy ,Physical therapy ,Humans ,Prednisone ,Medicine ,Female ,medicine.symptom ,business ,Paresis - Abstract
In an effort to refine and amplify the basis for clinical prognosis in Bell's palsy, 14 factors in a clinical study were analysed. From the results, it is still impossible to make a certain prognosis of recovery in the individual patient. However, it is obvious that, based on degree of paresis on assessment, and to a lesser degree the MAP value, at least a quantitative statement can be made.
- Published
- 1987
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