1. Relation between vitamin D and geriatric syndrome
- Author
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Eman Z. Azzam, Noha M El-Sabbagh, Nany Elgayar, and Doreen N. Younan
- Subjects
0301 basic medicine ,Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,030209 endocrinology & metabolism ,Timed Up and Go test ,Risk Assessment ,vitamin D deficiency ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,Vitamin D and neurology ,Humans ,Cognitive Dysfunction ,Prospective Studies ,Vitamin D ,Prospective cohort study ,Geriatric Assessment ,Depression (differential diagnoses) ,Aged ,030109 nutrition & dietetics ,Nutrition and Dietetics ,Mini–Mental State Examination ,medicine.diagnostic_test ,business.industry ,Tinetti test ,Middle Aged ,medicine.disease ,Vitamin D Deficiency ,Nutrition Assessment ,Time and Motion Studies ,Anxiety ,Female ,medicine.symptom ,business - Abstract
Summary Background Vitamin D level is a common health problem for elderly persons and it is associated with a decrease in physical performance, furthermore, it has been demonstrated that those with low serum vitamin D level has more risk of cognitive impairment, depression and anxiety. Aim The aim of the study was to estimate relation of vitamin D and geriatric syndrome. Methods A prospective study was done on 50 subjects who were normal elderly persons above 65 years. All the participants were subjected to full history taking, complete physical examination, laboratory assessment including serum 25-hydroxyvitamin D (OH)D by enzyme linked immunosorbent assay (ELISA) and geriatric syndrome assessment using 5 methods namely fall risk assessment using timed up &go test, mini-mental state examination (MMSE), geriatric depressive scale, mini nutritional assessment and Tinetti performance – oriented mobility assessment (POMA). Results The number of patients who were vitamin D deficient ( 20 ng/ml) were 11, 24 and 15 respectively. There was significant p association between low vitamin D level and female gender (p = 0.024), advanced age (p = 0.026), no-sun exposure jobs (p = 0.001) and nursing home residency. Mini mental state examination (p = 0.006) and geriatric depressive scale (p = 0.002) had a significant positive correlation with low vitamin D level while mini nutritional assessment (p = 1.000), timed up and go test (p = 0.225) and POMA score (p = 0.133) had no significant correlation with low vitamin D level. Conclusion There is correlation finding between vitamin D deficiency and advanced age, cognitive dysfunction, and depression.
- Published
- 2019