Search

Certain foods and dietary patterns have been associated with both inflammation and frailty. As chronic inflammation may play a role in frailty and disability, we examined the association of the inflammatory potential of diet with these outcomes. Data were taken from 1948 community-dwelling individuals ≥60 years old from the Seniors-ENRICA cohort, who were recruited in 2008–2010 and followed-up through 2012. Baseline diet data, obtained with a validated diet history, was used to calculate Shivappa's Dietary Inflammatory Index (DII), an "a priori" pattern score which is based on known associations of foods and nutrients with inflammation, and Tabung's Empirical Dietary Inflammatory Index (EDII), an " a posteriori " pattern score which was statistically derived from an epidemiological study. At follow-up, incident frailty was assessed with Fried's criteria, and incident limitation in instrumental activities of daily living (IADL) with the Lawton-Brody index. Statistical analyses were performed with logistic regression, and adjusted for the main confounders. Compared with individuals in the lowest tertile of DII, those in the highest tertile showed higher risk of frailty (odds ratio [OR] 2.48; 95% confidence interval [CI]: 1.42, 4.44, p-trend = 0.001) and IADL disability (OR: 1.96; 95% CI: 1.03, 3.86, p-trend = 0.035). By contrast, EDII did not show an association with these outcomes. The DII score was associated with slow gait speed, both as a low score in the Short Physical Performance Battery test (OR: 1.82; 95% CI: 1.27, 2.62, p-trend = 0.001) and as a positive Fried's criterion (OR: 1.64; 95% CI: 1.08, 2.51, p-trend = 0.021), which use different thresholds. DII predicted frailty and IADL while EDII did not. DII is able to measure diet healthiness in terms of physical decline in addition to avoidance of inflammation. ClinicalTrials.gov number, NCT01133093. [ABSTRACT FROM AUTHOR] more...

Summary Background & aims In normotensive and hypertensive individuals, blood pressure (BP) rises acutely during a few hours following coffee or caffeine consumption. However, the effect of habitual coffee consumption on BP and BP control is uncertain. The aim of this study was to assess the association of habitual coffee consumption on 24-h BP and BP control among older adults with hypertension. Methods Data were taken from the Seniors-Study on Nutrition and Cardiovascular Risk in Spain (ENRICA), a cross-sectional study conducted in 2012 among 1164 individuals aged ≥63 years. Habitual coffee consumption was assessed with a validated diet history. BP was recorded by 24-h ambulatory monitoring. Ambulatory hypertension was defined as BP ≥ 130/80 mm Hg or being under antihypertensive treatment, and uncontrolled BP was deemed as BP ≥ 130/80 mm Hg among hypertensives. Analyses were performed with linear and logistic regressions adjusted for the main confounders, including diet, time since diagnosis of hypertension and the number of antihypertensive drugs. Results Among the 715 hypertensive participants, those consuming ≥3 cups of coffee/day showed higher 24-h systolic BP (beta: 3.25 mm Hg, p value = 0.04) and diastolic BP (beta: 2.24 mm Hg, p value = 0.02) than non-coffee drinkers. Compared to non-coffee drinkers, the odds ratios (95% confidence interval) for uncontrolled BP among those consuming 1, 2, and ≥3 cups of coffee/day were, respectively: 1.95 (1.15–3.30), 1.41 (0.75–2.68), and 2.55 (1.28–5.09); p for trend = 0.05. The association was similar among individuals who were smokers, had excess weight (body mass index ≥25 kg/m 2 ), low adherence to the Mediterranean diet, or hypercholesterolemia. No association was found between coffee consumption and having a non-dipper BP pattern (<10% nocturnal decline in BP) among hypertensives. Conclusion Habitual coffee consumption was associated with uncontrolled BP in a hypertensive older population. [ABSTRACT FROM AUTHOR] more...

Summary: Background and aims: Understanding the effect of coffee on health-related quality of life (HRQL) would contribute to explain the mechanisms of the long-term effect of coffee on health. The aim of this study was to examine the association between coffee consumption and HRQL. Methods: Cross-sectional study conducted in 2008–2010 among 11,423 individuals representative of the Spanish population aged ≥18 years. Habitual coffee and food consumption was assessed with a validated diet history. HRQL was measured using the Spanish version of the SF-12 questionnaire. The analyses were performed using linear regression and adjusted for the main confounders. Results: Among men, no association was found between coffee consumption and the physical and mental composite summaries (PCS and MCS) of the SF-12. Among women, compared to those who did not consume coffee, habitual coffee drinkers showed similar scores on the PCS [beta coefficients (p value) for 1, 2, 3, and ≥4 cups/day: 0.49 (0.20), 0.62 (0.21), 0.50 (0.45), and 0.36 (0.59)]; but slightly better scores on the MCS [beta (p value): 1.58 (<0.001), 1.58 (0.004), 0.80 (0.31), and 1.22 (0.10)]. These results reflect mostly the consumption of non-filtered caffeinated coffee. Tea consumption and total caffeine intake did not show an association with HRQL. Conclusion: We found no evidence of an adverse effect of coffee on HRQL. These results are consistent with the null association between this beverage and several chronic diseases and all-cause mortality reported in many studies. The weak positive association of coffee with the MCS found among women needs further confirmation. [Copyright &y& Elsevier] more...