1. O.14 Adaptation of the human exocrine pancreas in response to a 10-day continuous intraduodenal infusion of a peptide diet rich in carbohydrate and poor in fat content
- Author
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E.O. Riecken, C. Emde, H. Menge, M. Zeitz, and R.-H. Liehr
- Subjects
chemistry.chemical_classification ,medicine.medical_specialty ,Nutrition and Dietetics ,Fat content ,business.industry ,Insulin ,medicine.medical_treatment ,Peptide ,Carbohydrate ,Critical Care and Intensive Care Medicine ,Enteral administration ,Endocrinology ,Gastric inhibitory polypeptide ,chemistry ,Internal medicine ,medicine ,Nasoduodenal Tube ,business ,Abdominal surgery - Abstract
Although in several studies the nutritional benefits of immediate postoperative enteral feeding have been confirmed, until now there is no investigation about the function of the "entero-insular axis" during this period. Eleven non-diabetic patients (8 ~, 3~ , 52 years (23-67) , 70 kg (52,7-88) , 172 cm (155-178) were tested before major abdominal surgery and at the first p.o. day. During each test three different quantities of gluoose (5 g, 15 g, 40 g) were given intraduodenally via a new developed thin nasoduodenal tube (@ 2 ram). Blood samples for determination of glucose, insulin, and gastric inhibitory polypeptide (GIP) were taken at -10, -5, 0, 5, 10, 15, 20, 30, 45, and 60 min. after each glucose load. Results: glucose (mg/100ml) insulin (~U/ml) GIP (pg/ml) fasting peak fasting peak fasting peak 5g 15g 409 59 159 409 59 159 409 preop. 85,5 105 114 136 17 31 63 137 1898 2276 1874 2480 postop. 111" 120" 142" 169" 17,5 52* 95* 163" 1207 2172 2354 2713
- Published
- 1983
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