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Start Over Author "Kousik Vankadari" Journal clinical nuclear medicine
8 results on '"Kousik Vankadari"'

5. 18F-FDG PET/CT Findings in a Rare Case of Paraneoplastic Vestibulocerebellar Syndrome Associated With Isolated Antiamphiphysin Antibodies

Author

Kousik Vankadari, Shivaram Rao Komandla, V Hemanth, Milap Milap, and Rukmini Mridula Kandadai

Subjects
Pathology, medicine.medical_specialty, Cerebellum, business.industry, Autoantibody, Nerve Tissue Proteins, General Medicine, Neurological disorder, medicine.disease, Paraneoplastic cerebellar degeneration, Paraneoplastic Cerebellar Degeneration, medicine.anatomical_structure, Extragonadal Germ Cell Tumor, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography, medicine, Humans, Radiology, Nuclear Medicine and imaging, Sensorineural hearing loss, Vestibulocerebellar syndrome, business, Stiff person syndrome, Autoantibodies
Abstract

Paraneoplastic cerebellar degeneration (PCD) is an immune-mediated neurological disease characterized by adaptive immune response against onconeural antigens physiologically expressed in the cerebellum. It is characterized by presence of highly specific onconeural autoantibodies such as anti-Yo, anti-Hu, anti-Ri, and anti-Ma2 in the serum and cerebrospinal fluid as diagnostic biomarkers. Antiamphiphysin autoantibody-related paraneoplastic encephalitis is a less commonly seen autoimmune neurological disorder usually presenting as stiff person syndrome. We present an unusual case of isolated antiamphiphysin antibody-related PCD presenting as vestibulocerebellar syndrome with associated sensorineural hearing loss and sensory neuropathy. FDG PET helped in topographical localization of brain lesion along with early detection of extragonadal germ cell tumor in the retroperitoneum.

Published
2021

6. Isolated Involvement of Prostate Gland by Immunoglobulin G4–Related Disease Diagnosed With the Help of FDG PET/CT

Author

Rajender Kumar, Rakesh Kochhar, Harmandeep Singh, Bhagwant Rai Mittal, Anish Bhattacharya, and Kousik Vankadari

Subjects
Male, medicine.medical_specialty, business.industry, Prostate, General Medicine, Disease, 030218 nuclear medicine & medical imaging, Young Adult, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Fluorodeoxyglucose F18, Immunoglobulin G, Positron Emission Tomography Computed Tomography, 030220 oncology & carcinogenesis, Immunoglobulin g4, medicine, Humans, Abdomen, Radiology, Nuclear Medicine and imaging, Fdg pet ct, Immunoglobulin G4-Related Disease, Radiology, Prostate gland, business
Abstract

Immunoglobulin G4 (IgG4)-related disease is known to mimic multiple malignancies and always poses a diagnostic challenge. We report a case of a 20-year-old young man, who presented with unexplained recurrent episodes of fever and pain abdomen. F-FDG PET/CT revealed intense focal FDG avidity in the prostate. On further workup, he had an elevated serum IgG4 level, and a clinical diagnosis of immunoglobulin G4-related disease was kept. A follow-up FDG PET/CT after glucocorticoid therapy revealed resolution of FDG avidity in the prostate with fall in serum IgG4 levels, hence confirming a diagnosis of atypical immunoglobulin G4-related disease involving isolated prostate gland.

Published
2019

8. Detection of Hepatic Encephalopathy on 18F-FDG PET/CT Brain Images in a Patient With Decompensated Liver Cirrhosis

Author

Bhagwant Rai Mittal, Harmandeep Singh, Radha K. Dhiman, Anish Bhattacharya, Rajender Kumar, and Kousik Vankadari

Subjects
Liver Cirrhosis, Male, medicine.medical_specialty, Cirrhosis, Malignancy, Lesion, 03 medical and health sciences, 0302 clinical medicine, Fluorodeoxyglucose F18, Positron Emission Tomography Computed Tomography, Ascites, Humans, Medicine, Radiology, Nuclear Medicine and imaging, Hepatic encephalopathy, Aged, Asterixis, Suspicious for Malignancy, business.industry, General Medicine, medicine.disease, Hepatic Encephalopathy, Hypermetabolism, 030211 gastroenterology & hepatology, Radiology, Radiopharmaceuticals, medicine.symptom, business, 030217 neurology & neurosurgery
Abstract

We present a case of decompensated liver cirrhosis with ascites, which had history of asterixis, impaired balance with swaying gait along with mild irritability since 1 month. F-fluorodeoxyglucose PET/CT (FDG-PET/CT) performed to rule out malignancy did not reveal any abnormal FDG avid lesion suspicious for malignancy but showed hypermetabolism in the bilateral basal ganglia and thalamus with reduced metabolism in cerebral cortices and cerebellum, suggesting hepatic encephalopathy.

Published
2018

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