1. PSMA-Ligand Uptake in Disseminated Epidermoid Cysts in a PSMA PET/CT of a Patient With Recurrent Prostate Cancer
- Author
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Ian Alberts, Ali Afshar-Oromieh, Clemens Mingels, Karl Peter Bohn, and Axel Rominger
- Subjects
Male ,Biochemical recurrence ,medicine.medical_specialty ,Pathology ,medicine.medical_treatment ,Epidermal Cyst ,Ligands ,urologic and male genital diseases ,Metastasis ,Prostate cancer ,Positron Emission Tomography Computed Tomography ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,610 Medicine & health ,Lymph node ,Edetic Acid ,Aged ,Retrospective Studies ,Prostatectomy ,business.industry ,Prostatic Neoplasms ,General Medicine ,Epidermoid cyst ,medicine.disease ,Ligand (biochemistry) ,medicine.anatomical_structure ,Histopathology ,Neoplasm Recurrence, Local ,business ,Oligopeptides - Abstract
PSMA PET/CT is routinely used for the detection of prostate cancer (PC). However, increased PSMA-ligand uptake has been described in a variety of benign and malignant tissues. A 71-year-old man with biochemical recurrence of PC initially treated with radical prostatectomy was referred for PSMA-ligand PET/CT. Apart from 1 lymph node with intense PSMA-ligand uptake, suspicious for metastasis, disseminated PSMA-ligand-avid subcutaneous lesions were seen. Histopathology of 1 of these lesions revealed an epidermoid cyst. Physicians should remain cognizant of non-PC-related causes of increased PSMA-ligand uptake, of which this case represent yet another example.
- Published
- 2021
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