1. Neurological outcomes following iatrogenic vascular injury during posterior atlanto-axial instrumentation
- Author
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Gustavo Pradilla, Oluwaseun O. Akinduro, Jonathan A Grossberg, Brian M. Howard, Griffin R. Baum, Gerald E. Rodts, and Faiz U. Ahmad
- Subjects
Adult ,medicine.medical_specialty ,Vertebral artery ,Neurological morbidity ,Iatrogenic Disease ,Arteriovenous fistula ,03 medical and health sciences ,Pseudoaneurysm ,0302 clinical medicine ,medicine.artery ,medicine ,Humans ,030212 general & internal medicine ,Intraoperative Complications ,Prospective cohort study ,Aged ,business.industry ,Retrospective cohort study ,General Medicine ,Middle Aged ,Vascular System Injuries ,medicine.disease ,Surgery ,Spinal Fusion ,Posterior inferior cerebellar artery ,Atlanto-Axial Joint ,Neurology (clinical) ,Complication ,business ,030217 neurology & neurosurgery - Abstract
Background Iatrogenic vascular injury is a feared complication of posterior atlanto-axial instrumentation. A better understanding of clinical outcome and management options following this injury will allow surgeons to better care for these patients. The object of the study was to systematically review the neurologic outcomes after iatrogenic vascular injury during atlanto-axial posterior instrumentation. Methods We performed a systematic review of the Medline database following PRISMA guidelines. In our analysis, we included any retrospective cohort studies, prospective cohort studies, case reports, cases series, or systematic reviews with patients who had undergone posterior atlanto-axial fusion via screw rod constructs (SRC) or transarticular screws (TAS) that reported a patient with an injury to an arterial vessel directly attributable to the surgical procedure. Results Sixty cases of vascular injury were reported in 2078 (2.9%) patients over 27 publications. The average age for this patient population was 55.7+/−17.9. Vascular injury following posterior C1/2 instrumentation resulted in ipsilateral stroke in 10.0% (n = 6/60) and non-persistent neurologic deficit in 6.7% (n = 4/60) of cases with the deficit being permanent (not including death) in 1.7% (n = 1/60) of cases. Four patients (6.7%) died. Arteriovenous fistula or pseudoaneurysm occurred in 8.3% (n = 5/60) and 3.3% (n = 2/60) of cases, respectively. Eight patients (13.3%) underwent endovascular repair of the injury with no permanent deficit. Conclusion Neurological morbidity after iatrogenic vascular injury during posterior C1/2 fixation is higher than previously reported in literature. Some patients may benefit from endovascular treatment. Surgeons should be aware of normal and anomalous vertebral artery anatomy to avoid this potentially catastrophic complication.
- Published
- 2016