1. Dynamics of methicillin-resistant Staphylococcus aureus and methicillin-susceptible Staphylococcus aureus carriage in pig farmers: a prospective cohort study
- Author
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van Cleef, B A G L, van Benthem, B H B, Verkade, E J M, van Rijen, M, Kluytmans-van den Bergh, M F Q, Schouls, L M, Duim, B, Wagenaar, Jaap, Graveland, H, Bos, M E H, Heederik, D, Kluytmans, J A J W, I&I RATIA-SIB, Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA-SIB, LS Klinisch Onderzoek Wagenaar, LS IRAS EEPI GRA (Gezh.risico-analyse), Medical Microbiology and Infection Prevention, CCA - Innovative therapy, I&I RATIA-SIB, Risk Assessment of Toxic and Immunomodulatory Agents, IRAS RATIA-SIB, LS Klinisch Onderzoek Wagenaar, and LS IRAS EEPI GRA (Gezh.risico-analyse)
- Subjects
Male ,Veterinary medicine ,Sus scrofa ,Prevalence ,MRSA ,medicine.disease_cause ,Risk Factors ,Epidemiology ,Prospective Studies ,Prospective cohort study ,Netherlands ,methicillin-susceptible Staphylococcusaureus ,pigs ,General Medicine ,Middle Aged ,Staphylococcal Infections ,Infectious Diseases ,Staphylococcus aureus ,Carrier State ,Female ,epidemiology ,Adult ,Microbiology (medical) ,medicine.medical_specialty ,Adolescent ,Coronacrisis-Taverne ,Nose ,methicillin-resistant Staphylococcus aureus ,MSSA ,ST398 ,Young Adult ,medicine ,Animals ,Humans ,Nasal carriage ,Aged ,Mouth ,business.industry ,the Netherlands ,biochemical phenomena, metabolism, and nutrition ,bacterial infections and mycoses ,Methicillin-resistant Staphylococcus aureus ,livestock ,Cross-Sectional Studies ,Carriage ,Dynamics of carriage ,business ,Methicillin Susceptible Staphylococcus Aureus ,methicillin-resistant Staphylococcus aureus, methicillin-susceptible Staphylococcus aureus - Abstract
Our purpose was to determine the dynamics of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) carriage and its determinants in persons working at pig farms, in order to identify targets for interventions. This prospective cohort study surveyed 49 pig farms in the Netherlands on six sampling dates in 1 year (2010-11). Nasal and oropharyngeal swabs were collected, as well as environmental surface samples from stables and house. Of 110 pig farmers, 38% were persistent MRSA nasal carriers. The average cross-sectional MRSA prevalence was 63%. Methicillin-susceptible S. aureus (MSSA) nasal carriage was associated with fewer MRSA acquisitions (prevalence rate (PR) = 0.47, p 0.02). In multivariate analysis, an age of 40-49 years (PR = 2.13, p 0.01), a working week of ≥40 h (PR=1.89, p 0.01), giving birth assistance to sows (PR=2.26, p 0.03), removing manure of finisher pigs (PR=0.48, p 0.02), and wearing a facemask (PR = 0.13, p 0.02) were significantly related with persistent MRSA nasal carriage. A higher MRSA exposure in stables was associated with MRSA in pig farmers (p
- Published
- 2014
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