1. Co-infections with hepatitis B and C viruses in human immunodeficiency virus-infected patients in Morocco
- Author
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Bouchra Kitab, H. Himmich, H. Issouf, Khadija Rebbani, Soumaya Benjelloun, A. Ouladlahsen, Lahcen Wakrim, Abdellah Akil, K. Marhoum El Filali, Fatima-Zohra Fakhir, Sayeh Ezzikouri, H Lamdini, A. Bensghir, and Ikram Brahim
- Subjects
Adult ,Male ,Microbiology (medical) ,medicine.medical_specialty ,genotype ,Hepatitis C virus ,prevalence ,Population ,medicine.disease_cause ,co-infection ,Antigen ,Genotype ,Epidemiology ,Medicine ,Humans ,education ,Chronic hepatitis ,Hepatitis B virus ,Hepatitis ,education.field_of_study ,human immunodeficiency virus ,business.industry ,Coinfection ,virus diseases ,General Medicine ,Hepatitis B ,Middle Aged ,medicine.disease ,Virology ,Hepatitis C ,digestive system diseases ,Morocco ,Infectious Diseases ,Immunology ,Female ,business - Abstract
Human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis Cvirus (HCV) are major public health concerns. We aimed to determine the prevalence of HBV and HCV infections among HIV-infected patients, and to identify the main circulating hepatitis strains in Morocco. The study was carried out in 503 HIV-infected patients. Our survey indicated that the prevalence of HIV/hepatitis co-infection was 10.6%; 5.2% of patients were HBV surface antigen positive, and 5.4% of patients were anti-HCV positive. Among the HBV surface antigen-positive group, HBV DNA sequencing identified exclusively genotype D (D1: 26.7%; D7: 73.3%) in accordance with what is found in the general population. In contrast, sequencing of HCV isolates produced an unusual subtype distribution with a decreasing order of prevalence: 1a, 3a (both 23.5%), 1b, 4a (both 17.6%), 1c (11.8%) and 6h (6%).
- Published
- 2013
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