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Clin Microbiol Infect 2010; 16: 630–632 A clinical Klebsiella pneumoniae isolate carrying the extended-spectrum β-lactamase gene variants blaSHV-40, blaTEM-116 and blaGES-7 was recovered. Cefoxitin and ceftazidime activity was most affected by the presence of these genes and an additional resistance to trimethoprim-sulphamethoxazole was observed. The blaGES-7 gene was found to be inserted into a class 1 integron. These results show the emergence of novel blaTEM and blaSHV genes in Brazil. Moreover, the presence of class 1 integrons suggests a great potential for dissemination of blaGES genes into diverse nosocomial pathogens. Indeed, the blaGES-7 gene was originally discovered in Enterobacter cloacae in Greece and, to our knowledge, has not been reported elsewhere. [ABSTRACT FROM AUTHOR]