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Start Over Author "Viva W. Tai" Journal clinical infectious diseases
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1. Effects of Recombinant Human Growth Hormone on Fat Distribution in Patients with Human Immunodeficiency Virus–Associated Wasting

Author

Clara Shayevich, Morris Schambelan, Kathleen Mulligan, Heather Algren, and Viva W. Tai

Subjects
Adult, Male, Microbiology (medical), medicine.medical_specialty, medicine.medical_treatment, HIV Infections, Cachexia, Fats, Metabolic Diseases, Weight loss, Internal medicine, Immunopathology, medicine, Humans, Distribution (pharmacology), Wasting, Retrospective Studies, Clinical Trials as Topic, Chemotherapy, Human Growth Hormone, business.industry, medicine.disease, Trunk, Recombinant Proteins, Infectious Diseases, Endocrinology, Lean body mass, Female, medicine.symptom, business
Abstract

In light of current interest in recombinant human growth hormone (GH) as a treatment for fat distribution abnormalities, we retrospectively evaluated regional changes in fat and lean body mass in a subset of subjects who participated in randomized, double-blind, placebo-controlled trials of GH for treatment of wasting. Treatment with a pharmacologic dose of GH (0.1 mg/kg/day) resulted in significant and sustained increases in lean body mass and losses of fat in both the trunk and appendicular regions.

Published
2002

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