1. Ebola Virus Persistence in Breast Milk After No Reported Illness: A Likely Source of Virus Transmission From Mother to Child
- Author
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Theresa Enkirch, Katrin Singethan, Victoria Amburgey, David L. Fitter, Sakoba Keita, Ousmane Faye, Daouda Sissoko, Fara Raymond Koundouno, Xavier Anglaret, Stephan Günther, Raymond Bruce Aylward, Benjamin A. Dahl, Mamoudou Harouna Djingarey, Miles W. Carroll, Boubacar Diallo, Sarah Meisel, Amadou A. Sall, N’Faly Magassouba, Sophie Duraffour, Mory Keita, Negar Aliabadi, Joseph Akoi Bore, Nicholas J. Loman, Denis Malvy, Antonio Mazzarelli, and Pierre Formenty
- Subjects
Adult ,Male ,0301 basic medicine ,Microbiology (medical) ,medicine.medical_specialty ,Mother to child transmission ,Breastfeeding ,Sequence Homology ,Disease ,Breast milk ,medicine.disease_cause ,real-time sequencing ,Persistence (computer science) ,asymptomatic carriage ,Ebola virus ,Young Adult ,03 medical and health sciences ,Semen ,Epidemiology ,Cluster Analysis ,Humans ,Medicine ,Ebola Virus ,Mother-to-child Transmission ,Real-time Sequencing ,Breast Milk ,Asymptomatic Carriage ,Phylogeny ,Milk, Human ,business.industry ,Transmission (medicine) ,Brief Report ,mother-to-child transmission ,Infant ,Sequence Analysis, DNA ,Hemorrhagic Fever, Ebola ,Ebolavirus ,Virology ,Infectious Disease Transmission, Vertical ,3. Good health ,030104 developmental biology ,Infectious Diseases ,Immunology ,breast milk ,RNA, Viral ,Female ,business - Abstract
A 9-month-old infant died from Ebola virus (EBOV) disease with unknown epidemiological link. While her parents did not report previous illness, laboratory investigations revealed persisting EBOV RNA in the mother’s breast milk and the father’s seminal fluid. Genomic analysis strongly suggests EBOV transmission to the child through breastfeeding.
- Published
- 2016