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Your search keyword '"Schmader, Kenneth E."' showing total 17 results
Start Over Author "Schmader, Kenneth E." Journal clinical infectious diseases
17 results on '"Schmader, Kenneth E."'

1. Performance of Urinalysis Parameters in Predicting Urinary Tract Infection: Does One Size Fit All?

Author

Advani, Sonali D, North, Rebecca, Turner, Nicholas A, Ahmadi, Sahra, Denniss, Julia, Francis, Adero, Johnson, Rachel, Hasan, Anum, Mirza, Faryal, Pardue, Sarah, Rao, Meghana, Rosshandler, Yasmin, Tang, Helen, Schmader, Kenneth E, and Anderson, Deverick J

Subjects
URINARY tract infection diagnosis, PREDICTIVE tests, SUPPURATION, RESEARCH funding, SEX distribution, RETROSPECTIVE studies, URINE, AGE distribution, URINALYSIS, MEDICAL records, ACQUISITION of data, NITRITES
Abstract

In a multihospital cohort study of 3392 patients, positive urinalysis parameters had poor positive predictive value for diagnosing urinary tract infection (UTI). Combined urinalysis parameters (pyuria or nitrite) performed better than pyuria alone for ruling out UTI. However, performance of all urinalysis parameters was poor in older women. [ABSTRACT FROM AUTHOR]

Published
2024
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2. A Phase 2 Clinical Trial to Evaluate the Safety, Reactogenicity, and Immunogenicity of Different Prime-Boost Vaccination Schedules of 2013 and 2017 A(H7N9) Inactivated Influenza Virus Vaccines Administered with and without AS03 Adjuvant in Healthy US Adults

Author

Rostad, Christina A, primary, Atmar, Robert L, additional, Walter, Emmanuel B, additional, Frey, Sharon, additional, Meier, Jeffery L, additional, Sherman, Amy C, additional, Lai, Lilin, additional, Tsong, Rachel, additional, Kao, Carol M, additional, Raabe, Vanessa, additional, El Sahly, Hana M, additional, Keitel, Wendy A, additional, Whitaker, Jennifer A, additional, Smith, Michael J, additional, Schmader, Kenneth E, additional, Swamy, Geeta K, additional, Abate, Getahun, additional, Winokur, Patricia, additional, Buchanan, Wendy, additional, Cross, Kaitlyn, additional, Wegel, Ashley, additional, Xu, Yongxian, additional, Yildirim, Inci, additional, Kamidani, Satoshi, additional, Rouphael, Nadine, additional, Roberts, Paul C, additional, Mulligan, Mark J, additional, and Anderson, Evan J, additional

Published
2024
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3. Editorial Commentary: Zoster Vaccine in Immunocompromised Patients: Time to Reconsider Current Recommendations

Author

Oxman, Michael N and Schmader, Kenneth E

Subjects
Medical Microbiology, Biomedical and Clinical Sciences, Good Health and Well Being, Antineoplastic Agents, Female, Herpes Zoster, Herpes Zoster Vaccine, Humans, Male, Neoplasms, cancer chemotherapy, herpes zoster, immunization, varicella-zoster virus, zoster vaccine, Biological Sciences, Medical and Health Sciences, Microbiology, Clinical sciences
Published
2014

5. Recommendations for the Management of Herpes Zoster

Author

Johnson, Robert W., Breuer, Judith, Gnann, John W., Levin, Myron J., Betts, Robert F., Gershon, Anne A., Oxman, Michael N., Schmader, Kenneth E., Tyring, Stephen K., Wallace, Mark S., and Whitley, Richard J.

Published
2007

8. Long-term Persistence of Zoster Vaccine Efficacy

Author

Shingles Prevention Study Group, Morrison, Vicki A., Johnson, Gary R., Schmader, Kenneth E., Levin, Myron J., Zhang, Jane H., Looney, David J., Betts, Robert, Gelb, Larry, Guatelli, John C., Harbecke, Ruth, Pachucki, Connie, Keay, Susan, Menzies, Barbara, Griffin, Marie R., Kauffman, Carol A., Marques, Adriana, Toney, John, Boardman, Kathy, Su, Shu-Chih, Li, Xiaoming, Chan, Ivan S. F., Parrino, Janie, Annunziato, Paula, and Oxman, Michael N.

Published
2015

9. Reply to Arroyo

Author

Schmader, Kenneth E., Levin, Myron J., Keay, Susan, Chan, Ivan S. F., Annunziato, Paula W., and Parrino, Janie

Published
2012
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11. Workshop on HIV Infection and Aging: What Is Known and Future Research Directions

Author

Effros, Rita B., Fletcher, Courtney V., Gebo, Kelly, Halter, Jeffrey B., Hazzard, William R., Horne, Frances McFarland, Huebner, Robin E., Janoff, Edward N., Justice, Amy C., Kuritzkes, Daniel, Nayfield, Susan G., Plaeger, Susan F., Schmader, Kenneth E., Ashworth, John R., Campanelli, Christine, Clayton, Charles P., Rada, Beth, Woolard, Nancy F., and High, Kevin P.

Published
2008
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12. Recommendations for the management of herpes zoster

Author

Dworkin, Robert H., Johnson, Robert W., Breuer, Judith, Gnann, John W., Levin, Myron J., Backonja, Miroslav, Betts, Robert F., Gershon, Anne A., Haanpaa, Maija L., McKendrick, Michael W., Nurmikko, Turo J., Oaklander, Anne Louise, Oxman, Michael N., Pavan-Langston, Deborah, Petersen, Karin L., Rowbotham, Michael C., Schmader, Kenneth E., Stacey, Brett R., Tyring, Stephen K., van Wijck, Albert J. M., Wallace, Mark S., Wassilew, Sawko W., and Whitley, Richard J.

Subjects
Shingles (Disease) -- Care and treatment, Shingles (Disease) -- Research, Shingles (Disease) -- Diagnosis, Shingles (Disease) -- Development and progression, Antiviral agents -- Usage, Medical case management -- Evaluation, Patients -- Care and treatment, Patients -- Management, Company business management, Health, Health care industry
Published
2007

13. Surgical site infection in the elderly population

Author

Kaye, Keith S., Schmader, Kenneth E., and Sawyer, Robert

Subjects
Aged -- Care and treatment, Communicable diseases -- Risk factors, Communicable diseases -- Care and treatment, Health, Health care industry
Published
2004

14. Treatment and prevention of postherpetic neuralgia. (Clinical Practice: Invited Article)

Author

Dworkin, Robert H. and Schmader, Kenneth E.

Subjects
Herpesvirus diseases -- Complications, Herpes, Neuralgia -- Care and treatment, Neuralgia -- Drug therapy, Gabapentin -- Usage, Lidocaine -- Usage, Opioids -- Usage, Nortriptyline -- Physiological aspects, Nortriptyline -- Evaluation, Nortriptyline -- Usage, Amitriptyline -- Physiological aspects, Amitriptyline -- Evaluation, Amitriptyline -- Usage, Varicella-zoster virus -- Physiological aspects, Health, Health care industry
Published
2003

15. Aging and Infectious Diseases: Workshop on HIV Infection and Aging: What Is Known and Future Research Directions

Author

Effros, Rita B., primary, Fletcher, Courtney V., additional, Gebo, Kelly, additional, Halter, Jeffrey B., additional, Hazzard, William R., additional, Horne, Frances McFarland, additional, Huebner, Robin E., additional, Janoff, Edward N., additional, Justice, Amy C., additional, Kuritzkes, Daniel, additional, Nayfield, Susan G., additional, Plaeger, Susan F., additional, Schmader, Kenneth E., additional, Ashworth, John R., additional, Campanelli, Christine, additional, Clayton, Charles P., additional, Rada, Beth, additional, Woolard, Nancy F., additional, and High, Kevin P., additional

Published
2008
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16. Long-term Persistence of Zoster Vaccine Efficacy.

Author

Morrison, Vicki A., Johnson, Gary R., Schmader, Kenneth E., Levin, Myron J., Zhang, Jane H., Looney, David J., Betts, Robert, Gelb, Larry, Guatelli, John C., Harbecke, Ruth, Pachucki, Connie, Keay, Susan, Menzies, Barbara, Griffin, Marie R., Kauffman, Carol A., Marques, Adriana, Toney, John, Boardman, Kathy, Su, Shu-Chih, and Li, Xiaoming

Subjects
HERPES zoster treatment, HERPES zoster vaccines, VACCINE effectiveness, LONG-term health care, POSTHERPETIC neuralgia, DISEASE incidence, VACCINES
Abstract

The Long-Term Persistence Substudy of the Shingles Prevention Study (SPS) assessed zoster vaccine efficacy in a subset of the SPS vaccine recipients followed for up to 11 years postvaccination. Vaccine efficacy was no longer statistically significant beyond 8 years postvaccination.Background. The Shingles Prevention Study (SPS) demonstrated zoster vaccine efficacy through 4 years postvaccination. A Short-Term Persistence Substudy (STPS) demonstrated persistence of vaccine efficacy for at least 5 years. A Long-Term Persistence Substudy (LTPS) was undertaken to further assess vaccine efficacy in SPS vaccine recipients followed for up to 11 years postvaccination. Study outcomes were assessed for the entire LTPS period and for each year from 7 to 11 years postvaccination.Methods. Surveillance, case determination, and follow-up were comparable to those in SPS and STPS. Because SPS placebo recipients were offered zoster vaccine before the LTPS began, there were no unvaccinated controls. Instead, SPS and STPS placebo results were used to model reference placebo groups.Results. The LTPS enrolled 6867 SPS vaccine recipients. Compared to SPS, estimated vaccine efficacy in LTPS decreased from 61.1% to 37.3% for the herpes zoster (HZ) burden of illness (BOI), from 66.5% to 35.4% for incidence of postherpetic neuralgia, and from 51.3% to 21.1% for incidence of HZ, and declined for all 3 outcome measures from 7 through 11 years postvaccination. Vaccine efficacy for the HZ BOI was significantly greater than zero through year 10 postvaccination, whereas vaccine efficacy for incidence of HZ was significantly greater than zero only through year 8.Conclusions. Estimates of vaccine efficacy decreased over time in the LTPS population compared with modeled control estimates. Statistically significant vaccine efficacy for HZ BOI persisted into year 10 postvaccination, whereas statistically significant vaccine efficacy for incidence of HZ persisted only through year 8. [ABSTRACT FROM PUBLISHER]

Published
2015

17. Epstein-Barr Virus and the Elderly Host

Author

Schmader, Kenneth E., van der Horst, Charles M., and Klotman, Mary E.

Abstract

The ability of the Epstein-Barr virus (EBV) to cause latent lifelong infection in the host and its capabilities of transformation may have important implications for the elderly host. Reports in the literature and hospital records were reviewed to determine the activity of EBV in the elderly. Seroepidemiologic surveys demonstrated that 90%–97% of adults more than 60 years old were seropositive for EBV. Geometric mean antibody titers and the percentage of individuals with high antibody titers to EBV increased with age — changes that were not associated with clinical illness. Only 29 cases of infectious mononucleosis have been reported in adults more than 60 years old. The elderly with infectious mononucleosis had significantly fewer occurrences of pharyngitis, lymphadenopathy, and splenomegaly when compared with young adults. The cases of two patients with illnesses that did not meet full criteria for infectious mononucleosis but may still have represented clinical manifestations of EBV infection are presented. Other EBV-associateddiseases reported in the elderly include nasopharyngeal carcinoma and possibly B cell lymphoproliferative disease but not a chronic mononucleosis-like syndrome.

Published
1989
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