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Start Over Author "Linda J, Harrison" Journal clinical infectious diseases
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1. Nasal and Plasma Severe Acute Respiratory Syndrome Coronavirus 2 RNA Levels Are Associated With Timing of Symptom Resolution in the ACTIV-2 Trial of Nonhospitalized Adults With Coronavirus Disease 2019

Author

Yijia Li, Linda J Harrison, Kara W Chew, Judy S Currier, David A Wohl, Eric S Daar, Teresa H Evering, Ryan Wu, Mark Giganti, Justin Ritz, Arzhang Cyrus Javan, Robert W Coombs, Carlee Moser, Michael D Hughes, Joseph J Eron, Davey M Smith, and Jonathan Z Li

Subjects
Microbiology (medical), Infectious Diseases
Abstract

Acute Coronavirus Disease 2019 symptoms limit daily activities, but little is known about its association with severe acute respiratory syndrome coronavirus 2 viral burden. In this exploratory analysis of placebo recipients in the ACTIV-2/A5401 platform trial, we showed that high anterior nasal RNA levels and detectable plasma RNA were associated with delayed symptom improvement.Clinical Trials Registration. https://clinicaltrials.gov/ct2/show/NCT04518410.

Published
2022
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