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Start Over Author "Gorse, Geoffrey J." Journal clinical infectious diseases
4 results on '"Gorse, Geoffrey J."'

2. Risk Factors for Healthcare Personnel Infection With Endemic Coronaviruses (HKU1, OC43, NL63, 229E): Results from the Respiratory Protection Effectiveness Clinical Trial (ResPECT).

Author

Cummings, Derek A T, Radonovich, Lewis J, Gorse, Geoffrey J, Gaydos, Charlotte A, Bessesen, Mary T, Brown, Alexandria C, Gibert, Cynthia L, Hitchings, Matthew D T, Lessler, Justin, Nyquist, Ann-Christine, Rattigan, Susan M, Rodriguez-Barradas, Maria C, Price, Connie Savor, Reich, Nicholas G, Simberkoff, Michael S, and Perl, Trish M

Subjects
WORK environment, OCCUPATIONAL roles, AEROSOLS, CONFIDENCE intervals, SICK people, COVID-19, MEDICAL personnel, CROSS infection, RESPIRATORY infections, RISK assessment, DESCRIPTIVE statistics, PERSONAL protective equipment, ODDS ratio, COVID-19 pandemic, DISEASE risk factors
Abstract

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) presents a large risk to healthcare personnel (HCP). Quantifying the risk of coronavirus infection associated with workplace activities is an urgent need. Methods We assessed the association of worker characteristics, occupational roles and behaviors, and participation in procedures with the risk of endemic coronavirus infection among HCP who participated in the Respiratory Protection Effectiveness Clinical Trial (ResPECT), a cluster randomized trial to assess personal protective equipment to prevent respiratory infections and illness conducted from 2011 to 2016. Results Among 4689 HCP seasons, we detected coronavirus infection in 387 (8%). HCP who participated in an aerosol-generating procedure (AGP) at least once during the viral respiratory season were 105% (95% confidence interval, 21%–240%) more likely to be diagnosed with a laboratory-confirmed coronavirus infection. Younger individuals, those who saw pediatric patients, and those with household members <5 years of age were at increased risk of coronavirus infection. Conclusions Our analysis suggests that the risk of HCP becoming infected with an endemic coronavirus increases approximately 2-fold with exposures to AGPs. Our findings may be relevant to the coronavirus disease 2019 (COVID-19) pandemic; however, SARS-CoV-2, the virus that causes COVID-19, may differ from endemic coronaviruses in important ways. Clinical Trials Registration NCT01249625. [ABSTRACT FROM AUTHOR]

Published
2021
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3. Risk Factors for Healthcare Personnel Infection With Endemic Coronaviruses (HKU1, OC43, NL63, 229E): Results from the Respiratory Protection Effectiveness Clinical Trial (ResPECT)

Author

Cummings, Derek A T, primary, Radonovich, Lewis J, additional, Gorse, Geoffrey J, additional, Gaydos, Charlotte A, additional, Bessesen, Mary T, additional, Brown, Alexandria C, additional, Gibert, Cynthia L, additional, Hitchings, Matthew D T, additional, Lessler, Justin, additional, Nyquist, Ann-Christine, additional, Rattigan, Susan M, additional, Rodriguez-Barradas, Maria C, additional, Price, Connie Savor, additional, Reich, Nicholas G, additional, Simberkoff, Michael S, additional, and Perl, Trish M, additional

Published
2020
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4. Male Genital Tuberculosis: A Review of the Literature with Instructive Case Reports

Author

Gorse, Geoffrey J. and Belshe, Robert B.

Abstract

The prevalence of extrapulmonary tuberculosis, including cases at male genital sites, has remained relatively constant during the past two decades in the United States. The most common genital sites of tuberculous infection are the epididymis and prostate; the testicle is infected in a lower proportion of cases. The usual modes of genital involvement include descending infection from the kidneys, intracanalicular or direct extension from neighboring foci in the genital tract, and hematogenous seeding. Local symptoms are usually insidious and progressive. Systemic manifestations such as fever, chills, and sweats are infrequently present in isolated genital tuberculosis. Tuberculous genital infection can be confused with other bacterial (including nontuberculous mycobacterial) infections, fungal disease, tumors, and cysts as well as with a number of less common illnesses. Although some diagnostic and therapeutic indications for surgical excision still exist, the preferred approach to treatment is primarily multiple-drug antituberculous chemotherapy.

Published
1985
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