1. Rates of Postoperative Complications among Human Immunodeficiency Virus–Infected Women Who Have Undergone Obstetric and Gynecologic Surgical Procedures
- Author
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Manfred Stauber, Bernd H. Belohradsky, Olaf Dathe, Daniela Reindell, Thomas Grubert, Lutz Gürtler, and Ralph Kästner
- Subjects
Adult ,Microbiology (medical) ,medicine.medical_specialty ,medicine.medical_treatment ,Obstetric Surgical Procedures ,HIV Infections ,Gynecologic Surgical Procedures ,Postoperative Complications ,Acquired immunodeficiency syndrome (AIDS) ,Risk Factors ,Humans ,Medicine ,Antibiotic prophylaxis ,Risk factor ,Sida ,biology ,business.industry ,Immunity ,Odds ratio ,biology.organism_classification ,medicine.disease ,Curettage ,Surgery ,Women's Health Services ,Infectious Diseases ,Female ,Morbidity ,business ,Complication ,Abdominal surgery - Abstract
Clinical observations indicate that human immunodeficiency virus (HIV)‐positive women experience more postoperative problems than do HIV-negative women. To obtain a better estimate of the individual risk of postoperative morbidity among HIV-infected women, and to determine which procedures pose the greatest risk, we performed a retrospective case-control study in which we assessed the outcomes after 235 obstetric and gynecologic surgical procedures. For purposes of comparison, an HIV-negative control patient was matched for each of the 235 surgical procedures performed, on the basis of the type of procedure and patient age. We found a significantly greater number of postoperative complications among the HIV-positive women. Higher complication rates occurred after abdominal surgery (odds ratio [OR], 3.6; ) and curettage (OR, 7.7; P p .001 ). Among HIV-infected women, the risk of complications was associated with immune status. AntiP p .06 retroviral therapy and standard perioperative antibiotic prophylaxis did not decrease the risk of complications. Indications for performing abdominal surgery and curettage on HIV-infected women should be carefully weighed against the potential risk of postoperative complications.
- Published
- 2002