1. Xpert Ultra Assay on Stool to Diagnose Pulmonary Tuberculosis in Children
- Author
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S. M. Mazidur Rahman, Shahriar Ahmed, Sayeeda Anwar, Mohammod Jobayer Chisti, Shakil Ahmed, Hemant Deepak Shewade, Sabrina Choudhury, Pruthu Thekkur, Rupali Sisir Banu, Mohammad Khaja Mafij Uddin, Shamiul Islam, Senjuti Kabir, Nazneen Akhter Banu, Rumana Nasrin, Kishor Kumar Paul, Razia Khatun, and Sayera Banu
- Subjects
Microbiology (medical) ,medicine.medical_specialty ,childhood TB ,Tuberculosis ,Induced sputum ,Stool specimen ,Sensitivity and Specificity ,Tertiary care ,World health ,Mycobacterium tuberculosis ,Feces ,fluids and secretions ,Pulmonary tuberculosis ,Internal medicine ,medicine ,Humans ,Xpert Ultra ,stool ,Xpert ,Child ,Antibiotics, Antitubercular ,Tuberculosis, Pulmonary ,Bangladesh ,biology ,business.industry ,Sputum ,biology.organism_classification ,medicine.disease ,Major Articles and Commentaries ,Cross-Sectional Studies ,Infectious Diseases ,AcademicSubjects/MED00290 ,SORT IT ,Rifampin ,medicine.symptom ,business - Abstract
Background The World Health Organization recommends the Xpert MTB/RIF Ultra assay for diagnosing pulmonary tuberculosis (PTB) in children. Though stool is a potential alternative to respiratory specimens among children, the diagnostic performance of Xpert Ultra on stool is unknown. Thus, we assessed the diagnostic performance of Xpert Ultra on stool to diagnose PTB in children. Methods We conducted a cross-sectional study among consecutively recruited children (, Xpert Ultra may be used on stool, an easy-to-obtain specimen, for childhood pulmonary tuberculosis diagnosis. Future studies with follow-up and clinical evolution are needed to provide insight on management of children with trace call.
- Published
- 2020