156 results on '"Hafler, David A."'
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2. Characterization of in vivo expanded OspA-specific human T-cell clones
3. Functional analysis of highly defined, FACS-isolated populations of human regulatory CD4 +CD25 + T cells
4. Decreases in Interleukin-4 Secretion by Invariant CD4−CD8−Vα24JαQ T Cells in Peripheral Blood of Patients with Relapsing–Remitting Multiple Sclerosis
5. Efficient Activation of Self-reactive T Cells from MS Patients with Altered Synapse Formation
6. Dissecting the Functional Consequences of the Validated Multiple Sclerosis Susceptibility Allele in TNFRSF1A
7. Interleukin-9 Secretion by Human Th17 Cells is Inducible by TGF-β and Proinflammatory Cytokines and is Increased in Autoimmune Diabetes
8. Characterization of the Myelin Specific Autoantibodies in Acute Disseminated Encephalomyelitis
9. IL-12 Induces Human CD4+CD45RA-CD25hiCD127low/neg Regulatory T Cells to Secrete IFNγ and IL-10 and Acquire a Non-regulatory Effector Phenotype
10. Altered Synapse Formation by Self-reactive T Cells from MS Patients
11. IL-1 Receptor Expression on Human Regulatory T Cells and IL-1β's Role in Reducing Suppression
12. Monocytes from Patients with Type 1 Diabetes Have Increased Gene Expression of Pro-inflammatory Cytokines or IL-10
13. Regulation of Immunological Tolerance and Autoimmunity by the Enzyme Sialic Acid Acetylesterase (SIAE)
14. The PhenoGenetic Project: A Living Biobank Enabling the Study of Human Genetic and Immunologic Variation
15. OR.39. Enumeration and Phenotype of Autoreactive B Cells in Pancreatic Draining Lymph Nodes from Type 1 Diabetes Subjects
16. S.132. Cathepsin S Regulates MHC Class II Processing in Human CD4+HLA-DR+T Cells
17. F.108. DNA Methylation of the Human FoxP3 Locus Differs Significantly Between Functionally Distinct Subpopulations of CD4+CD25high Human Regulatory T Cells
18. OR.31. Human TIM-3 Regulates Th1 and Th17 Cytokines
19. S.119. CD127 and HLA DR Define Functionally Distinct Human Tregs- One Subsets Exhibits Decreased Activity in Multiple Sclerosis
20. OR.55. Transforming Growth Factor-beta is Crucial for the Differentiation and Regulation of Interleukin 9-producing Human CD4+T Cells
21. F.89. Elucidating the Antigen Specificity of B Cells Present within the CNS Lesions of Patients with MS
22. OR.43. Comparative Analysis of B Cell Repertoires Among Lesions and Normal Appearing White Matter in the Multiple Sclerosis Central Nervous System
23. T.22. Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Pro-inflammatory Cytokines Inducing Th17 Cells
24. OR.4. Cellular Senescence in Terminally Differentiated Human CD4+CD25hi IL-7Rneg HLA-DR+Regulatory T Cells
25. S.67. Detection of Myelin Reactive CD4+Cells in the Peripheral Blood of Patients with Multiple Sclerosis using MHC Class II Tetramers
26. Concurrent detection of secreted products from human lymphocytes by microengraving: Cytokines and antigen-reactive antibodies
27. Sa.115. IL7R and HLA-Class II selected FoxP3+ Natural Regulatory T Cells (nTregs) Represent Effector nTregs, Precursor nTregs, and Induced nTregs
28. F.14. Autoantibodies to Myelin Oligodendrocyte Glycoprotein in Pediatric MS
29. Flt3, a New Regulator of IL-10 Production by Human T Cells, Identified Using an RNAi Library
30. OR.41. IL-21 and TGF-β are Required for Differentiation of Human Th17 Cells
31. Sa.77. Ex Vivo Activated State of Type 1 Diabetic Monocytes
32. OR.39. Differentiation of Natural Human CD4+CD25high Tregs to Th17 Effector Cells
33. F.33. Genetic Variants that Control the Expression of MHC Genes Do Not Affect Susceptibility to Multiple Sclerosis
34. Sa.114. IL-10 and Granzyme B Inhibits Suppression by Human DR+ Effector nTregs
35. Sa.102. Discovery and Characterization of Novel Human TIM-3 Splice Variants
36. F.34. Changes in the CD8dimCD4- Cell Population Parallel Disease Activity in Treated Multiple Sclerosis Subjects
37. OR.102. The CD58 Pathway is Implicated in MS Susceptibility
38. Sa.109. Allelic and Phenotypic Heterogeneity at the Autoimmune Susceptibility Locus IL2RA
39. Su.86. Automated High-dimensional Flow Cytometric Data Analysis
40. Large Scale Immunoprofiling Uncovers Population Structure in Untreated MS Subjects and Highlights the Role of NK Cells
41. An Association Between the Autoimmune Susceptibility Locus CTLA4 and Alterations in Proximal TCR Signaling in Healthy Human Volunteers
42. Characterization of Single B Cell Immunoglobulin Variable Region Genes Derived from Infiltrated Muscle Tissue of Subjects with Inflammatory Myopathies
43. Human Glioblastoma Multiforme (GBM) Tumors are Enriched for Strongly Suppressive, Apoptosis Resistant, DR+ Tregs
44. Dysregulation of the TIM-3-Galectin-9 Pathway in Type I Diabetic T Cells
45. TIM-3 is a Negative Regulator of Human Th1 Cells
46. Defect in TIM-3 Regulation of CD4+ T Cells in a Human Autoimmune Disease
47. Improving Elispot to Detect Antigen Specific T Cells
48. Haplotype-specific Use of Lysosomal Proteases Can Modulate the Class II MHC Peptide Repertoire but Does Not Impair Invariant Chain Degradation in Human Antigen Presenting Cells
49. IL-10 Both Inhibits Treg Suppressive Activity and is a Survival Factor for Human Natural Tregs
50. A Genome-wide Screen for Genetic Variants Affecting the Expression of Immunologically Relevant Cell Surface Markers
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