1. Rare presentations of COVID-19: PRES-like leukoencephalopathy and carotid thrombosis
- Author
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Florence X. Doo, Shanna Patterson, Gassan Kassim, Daniel R. Lefton, Puneet Belani, and Hien Pham
- Subjects
Nervous system ,Pediatrics ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Pneumonia, Viral ,Anosmia ,Article ,Leukoencephalopathy ,Altered Mental Status ,Leukoencephalopathies ,Carotid thrombosis ,Pandemic ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Carotid Artery Thrombosis ,Pandemics ,Stroke ,SARS-CoV-2 ,business.industry ,COVID-19 ,medicine.disease ,medicine.anatomical_structure ,Radiology Nuclear Medicine and imaging ,medicine.symptom ,Coronavirus Infections ,Infection ,business - Abstract
Coronavirus disease 2019 (COVID-19) is a global pandemic, and it is increasingly important that physicians recognize and understand its atypical presentations. Neurological symptoms such as anosmia, altered mental status, headache, and myalgias may arise due to direct injury to the nervous system or by indirectly precipitating coagulopathies. We present the first COVID-19 related cases of carotid artery thrombosis and acute PRES-like leukoencephalopathy with multifocal hemorrhage., Highlights • COVID-19 may manifest with neurological symptoms • SARS-CoV-2 may have direct neurologic effects due to endothelial invasion, such as our case of PRES-like leukoencephalopathy. • Indirect effects may include coagulation cascade disruption, resulting in unusual thrombosis and large vessel occlusions.
- Published
- 2021
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