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Your search keyword '"Adrian B. Levine"' showing total 2 results
Start Over Author "Adrian B. Levine" Journal clinical case reports
2 results on '"Adrian B. Levine"'

1. NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

Author

Heidi M. Britton, Adrian B. Levine, Yaoqing Shen, Karen Mungall, Jonathan Serrano, Matija Snuderl, Erin Pleasance, Steven J. M. Jones, Janessa Laskin, Marco A. Marra, Shahrad R. Rassekh, Rebecca Deyell, Stephen Yip, Sylvia Cheng, and Chris Dunham

Subjects
Medicine, Medicine (General), R5-920
Abstract

Abstract This is the first report of a NACC2‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profiling in cancer care.

Published
2021
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2. NTRK2 Fusion driven pediatric glioblastoma: Identification of oncogenic Drivers via integrative Genome and transcriptome profiling

Author

Matija Snuderl, Rebecca J. Deyell, Marco A. Marra, Chris Dunham, Sylvia Cheng, Janessa Laskin, Jonathan Serrano, Karen Mungall, Erin Pleasance, Steven J.M. Jones, Heidi Britton, Adrian B. Levine, Stephen Yip, Shahrad Rod Rassekh, and Yaoqing Shen

Subjects
Cerebellar Glioblastoma, Pediatric glioblastoma, lcsh:Medicine, Case Report, Computational biology, Case Reports, 030204 cardiovascular system & hematology, Genome, 03 medical and health sciences, 0302 clinical medicine, Medicine, Transcriptome profiling, neoplasms, lcsh:R5-920, Oncogene, business.industry, lcsh:R, Cancer, General Medicine, medicine.disease, nervous system diseases, 030220 oncology & carcinogenesis, Identification (biology), lcsh:Medicine (General), business, Glioblastoma
Abstract

This is the first report of a NACC2‐NTRK2 fusion in a histological glioblastoma. Oncogenomic analysis revealed this actionable fusion oncogene in a pediatric cerebellar glioblastoma, which would not have been identified through routine diagnostics, demonstrating the value of clinical genome profiling in cancer care.

Published
2021

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