1. Depletion of antioxidants is associated with no-reflow phenomenon in acute myocardial infarction
- Author
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Hideyuki Takaoka, Hidenari Matsumoto, Nobutaka Inoue, Toru Ozawa, Satoshi Watanabe, Hiroyuki Masai, Toshiro Shinke, Katsuya Hata, Ryohei Yoshikawa, and Mitsuhiro Yokoyama
- Subjects
medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Vitamin E ,Percutaneous coronary intervention ,General Medicine ,medicine.disease ,medicine.disease_cause ,Coronary circulation ,medicine.anatomical_structure ,Internal medicine ,Conventional PCI ,No reflow phenomenon ,cardiovascular system ,medicine ,Cardiology ,cardiovascular diseases ,Myocardial infarction ,Cardiology and Cardiovascular Medicine ,business ,TIMI ,Oxidative stress - Abstract
Background: No-reflow phenomenon is observed in approximately one-third of patients after percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI), and is associated with poor functional and clinical outcomes. On the other hand, the formation of free radicals in vasculature exerts deleterious effects on coronary microcirculation. Hypothesis: We hypothesized that redox state in coronary circulation may play a crucial role in no-reflow phenomenon in AMI. Methods: Consecutive 26 patients with first AMI who underwent primary PCI
- Published
- 2004
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