1. A simple, rapid micro-latex fixation test.
- Author
-
Cicciarelli JC, Terasaki PI, Chia D, Barnett EV, Mickey MR, Prince S, Iwaki Y, and Shirahama S
- Subjects
- Adult, Aged, Aging, Antilymphocyte Serum, Arthritis, Rheumatoid immunology, B-Lymphocytes immunology, Child, Preschool, Double-Blind Method, HLA Antigens immunology, Humans, Infant, Infant, Newborn, Kidney Transplantation, Middle Aged, Regression Analysis, Renal Dialysis, Rheumatoid Factor, Sjogren's Syndrome immunology, Latex Fixation Tests methods
- Abstract
A micro-latex fixation test (LFT) for the determination of rheumatoid factor (RF) is presented. Its advantages compared to similar tests are greater precision, simplicity, increased sensitivity, lower cost, reproducibility and adaptibility to large-scale testing. Micro-LFT titres are presented from a wide range of sample populations. The majority of normal samples show measureable titres whereas rheumatoid patients show high titres. A large sampling of pre- and post-transplant sera from kidney patients was studied and the micro-LFT titres were in the range of normal persons. The transplant sera were tested for lymphocytotoxic antibodies and no correlation was observed with the micro-LFT titres.
- Published
- 1979