Search

Vibratory angio-oedema is a rare form of physical urticaria characterized by pruriginous weals and angio-oedema at the site of exposure to vibration. Severe treatment-resistant disease can occur, and is associated with significant disability. Therapy with omalizumab, a monoclonal IgG anti-IgE antibody, has been shown to be successful in several types of physical urticaria. We report a patient with vibratory angio-oedema for whom all standard treatments for urticaria, including omalizumab, failed to show a clinical benefit. Finally, ketotifen was tried, and unexpectedly reduced symptoms significantly. Ketotifen may thus represent a therapeutic option in patients with treatment-resistant vibratory angio-oedema. [ABSTRACT FROM AUTHOR]

The article presents a case study of a 57-year-old patient who had experienced reddening of the hands and feet. The patient was diagnosed with erythema scarlatiniforme desquamativum recidivans (ESDR) or Féreéol-Besnier disease. The patient was asked to use topical corticosteroids, emollients and chinosol, a topical disinfectant, in the bath.

The article discusses the case of a 56-year-old man with pityriasis rubra pilaris (PRP) and tuberculosis (TB) prophylaxis, which are manifested as lesions. It states that physical and histological examination yielded results consistent with PRP diagnosis including follicular hyperkeratotic papules, hyperparakeratosis, and hypergranulosis. It also says that the patient is treated with infusions of intravenous infliximab and had complete hyperkeratosis and erythema remission in 30 weeks.