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Your search keyword '"Kim, Han-Bi"' showing total 2 results
Start Over Author "Kim, Han-Bi" Journal clinical & experimental allergy
2 results on '"Kim, Han-Bi"'

1. The transient receptor potential vanilloid‐3 (TRPV3) channel in epidermal keratinocytes induce thymic interstitial lymphopoietin: Implications for TRPV3‐mediated itch pathways

Author

Um, Ji Young, primary, Kim, Han Bi, additional, Shim, Won‐Sik, additional, Lee, Wook Joo, additional, Lee, So Yeon, additional, Park, Jin Seo, additional, Kim, Jin Cheol, additional, Kwak, In Suk, additional, Chung, Bo Young, additional, Park, Chun Wook, additional, and Kim, Hye One, additional

Published
2023
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2. The transient receptor potential vanilloid‐3 (TRPV3) channel in epidermal keratinocytes induce thymic interstitial lymphopoietin: Implications for TRPV3‐mediated itch pathways.

Author

Um, Ji Young, Kim, Han Bi, Shim, Won‐Sik, Lee, Wook Joo, Lee, So Yeon, Park, Jin Seo, Kim, Jin Cheol, Kwak, In Suk, Chung, Bo Young, Park, Chun Wook, and Kim, Hye One

Subjects
*ITCHING, *CARVACROL, *TRPV cation channels, *TRP channels, *KERATINOCYTES
Abstract

This article discusses the role of the transient receptor potential vanilloid-3 (TRPV3) channel in inducing thymic interstitial lymphopoietin (TSLP) and its implications for itch pathways. The study found that TRPV3 activation regulates TSLP expression through calcium influx and the calcineurin/NFAT/NF-kB pathway. Carvacrol, a compound that activates TRPV3, was shown to increase TSLP and calcium influx, suggesting its involvement in TRPV3-mediated itch pathways. The findings provide insights into the molecular mechanisms of chronic pruritus and potential therapeutic targets for inflammatory skin diseases. [Extracted from the article]

Published
2024
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