1. Active Participation in Outpatient Cardiac Rehabilitation Is Associated With Better Prognosis After Coronary Artery Bypass Graft Surgery ― J-REHAB CABG Study ―
- Author
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Haruki Itoh, Masatoshi Nagayama, Takashi Masuda, Kenji Ueshima, Hitoshi Adachi, Ryuji Nohara, Masahiro Kohzuki, Kazuto Omiya, Yoichi Goto, Shigeru Makita, Hideki Origuchi, Shin Ichi Momomura, and Hiroyuki Daida
- Subjects
Male ,medicine.medical_specialty ,Time Factors ,Health Status ,Coronary Artery Disease ,030204 cardiovascular system & hematology ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Ambulatory Care ,medicine ,Clinical endpoint ,Humans ,cardiovascular diseases ,030212 general & internal medicine ,Myocardial infarction ,Coronary Artery Bypass ,Aged ,Retrospective Studies ,Cardiac Rehabilitation ,Exercise Tolerance ,Unstable angina ,business.industry ,VO2 max ,Recovery of Function ,General Medicine ,Middle Aged ,medicine.disease ,Exercise Therapy ,Surgery ,Treatment Outcome ,medicine.anatomical_structure ,Heart failure ,Cohort ,Female ,Cardiology and Cardiovascular Medicine ,business ,Mace ,Artery - Abstract
BACKGROUND There is little evidence regarding the effect of outpatient cardiac rehabilitation (CR) on exercise capacity or the long-term prognosis in patients after coronary artery bypass graft surgery (CABG). This study aimed to determine whether participation in outpatient CR improves exercise capacity and long-term prognosis in post-CABG Japanese patients in a multicenter cohort.Methods and Results:We enrolled 346 post-CABG patients who underwent cardiopulmonary exercise testing during early (2-3 weeks) and late (3-6 months) time points after surgery. They formed the Active (n=240) and Non-Active (n=106) CR participation groups and were followed for 3.5 years. Primary endpoint was a major adverse cardiac event (MACE): all-cause death or rehospitalization for acute myocardial infarction/unstable angina/worsening heart failure. Peak oxygen uptake at 3-5 months from baseline was significantly more increased in Active than in Non-Active patients (+26±24% vs. +19±20%, respectively; P
- Published
- 2020
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