1. Association of Cancer With Outcomes in Patients Hospitalized for Heart Failure
- Author
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Katsuhito Fujiu, Kojiro Morita, Hidehiro Kaneko, Hiroyuki Kiriyama, Nobuaki Michihata, Hideo Yasunaga, Hidetaka Itoh, Haruki Yotsumoto, Norifumi Takeda, Hiroyuki Morita, Issei Komuro, Tatsuya Kamon, and Taisuke Jo
- Subjects
Male ,medicine.medical_specialty ,Databases, Factual ,Comorbidity ,030204 cardiovascular system & hematology ,Logistic regression ,Risk Assessment ,Metastasis ,03 medical and health sciences ,0302 clinical medicine ,Japan ,Risk Factors ,Neoplasms ,Internal medicine ,Epidemiology ,Prevalence ,medicine ,Humans ,Hospital Mortality ,Generalized estimating equation ,Aged ,Retrospective Studies ,Aged, 80 and over ,Heart Failure ,business.industry ,Cancer ,General Medicine ,Odds ratio ,Prognosis ,medicine.disease ,Hospitalization ,030220 oncology & carcinogenesis ,Heart failure ,Concomitant ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
BACKGROUND The complex clinical status of heart failure (HF) patients with concomitant cancer is gaining clinical interest. This study sought to explore the prevalence of cancer in patients with HF and its effect on outcomes using a nationwide inpatient database.Methods and Results:In total, 447,818 HF patients who were admitted and discharged between January 2010 and March 2018 were studied and included in the Diagnosis Procedure Combination (DPC) database. The median age was 81 years; 238,192 patients (53.2%) were men and 25,951 (5.8%) had concomitant cancer. The prevalence of cancer peaked in patients aged in their 70 s and 80 s and increased with time. Patients with cancer were older and more likely to be male. Cigarette smoking was more common in patients with cancer. Patients with cancer more frequently had infectious complications during hospitalization. Advanced medical procedures were less frequently performed for patients with cancer. In-hospital mortality was higher in patients with cancer than those without (10.0% vs. 6.7%, P
- Published
- 2020