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Your search keyword '"Abraham, William T."' showing total 24 results
Start Over Author "Abraham, William T." Journal circulation: heart failure
24 results on '"Abraham, William T."'

1. A Composite Score Summarizing Use and Dosing of Evidence-Based Medical Therapies in Heart Failure: A Nationwide Cohort Study

Author

Johansen, Niklas Dyrby, Vaduganathan, Muthiah, Zahir, Deewa, Fiuzat, Mona, DeFilippis, Ersilia M., Januzzi, James L., Butler, Javed, O’Connor, Christopher M., Abraham, William T., Psotka, Mitchell A., McMurray, John J.V., Dewan, Pooja, Claggett, Brian L., Solomon, Scott D., Modin, Daniel, Butt, Jawad H., Jensen, Jens Ulrik Stæhr, Schou, Morten, Torp-Pedersen, Christian, Køber, Lars, Gislason, Gunnar H., and Biering-Sørensen, Tor

Published
2023
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3. Lower Rates of Heart Failure and All-Cause Hospitalizations During Pulmonary Artery Pressure-Guided Therapy for Ambulatory Heart Failure: One-Year Outcomes From the CardioMEMS Post-Approval Study

Author

Shavelle, David M., Desai, Akshay S., Abraham, William T., Bourge, Robert C., Raval, Nirav, Rathman, Lisa D., Heywood, J. Thomas, Jermyn, Rita A., Pelzel, Jamie, Jonsson, Orvar T., Costanzo, Maria Rosa, Henderson, John D., Brett, Marie-Elena, Adamson, Philip B., and Stevenson, Lynne W.

Published
2020
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6. Contemporary Characteristics and Outcomes in Chagasic Heart Failure Compared With Other Nonischemic and Ischemic Cardiomyopathy

Author

Shen, Li, Ramires, Felix, Martinez, Felipe, Bodanese, Luiz Carlos, Echeverría, Luis Eduardo, Gómez, Efraín A., Abraham, William T., Dickstein, Kenneth, Køber, Lars, Packer, Milton, Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Zile, Michael R., Jhund, Pardeep S., Gimpelewicz, Claudio R., and McMurray, John J.V.

Published
2017
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10. Early Reduction in Ambulatory Pulmonary Artery Pressures After Initiation of Sacubitril/Valsartan

Author

Desai, Akshay S., primary, Heywood, J. Thomas, additional, Rathman, Lisa, additional, Abraham, William T., additional, Adamson, Philip, additional, Brett, Marie-Elena, additional, Costanzo, Maria R., additional, Lamba, Sumant, additional, Raval, Nirav, additional, Shavelle, David, additional, Sood, Poornima, additional, and Stevenson, Lynne W., additional

Published
2021
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12. Risk Factor Burden, Heart Failure, and Survival in Women of Different Ethnic Groups

Author

Breathett, Khadijah, primary, Leng, Iris, additional, Foraker, Randi E., additional, Abraham, William T., additional, Coker, Laura, additional, Whitfield, Keith E., additional, Shumaker, Sally, additional, Manson, JoAnn E., additional, Eaton, Charles B., additional, Howard, Barbara V., additional, Ijioma, Nkechinyere, additional, Cené, Crystal W., additional, Martin, Lisa W., additional, Johnson, Karen C., additional, Klein, Liviu, additional, Rossouw, Jacques, additional, Ludlam, Shari, additional, Burwen, Dale, additional, McGowan, Joan, additional, Ford, Leslie, additional, Geller, Nancy, additional, Anderson, Garnet, additional, Prentice, Ross, additional, LaCroix, Andrea, additional, Kooperberg, Charles, additional, Stefanick, Marcia L., additional, Jackson, Rebecca, additional, Thomson, Cynthia A., additional, Wactawski-Wende, Jean, additional, Limacher, Marian, additional, Wallace, Robert, additional, and Kuller, Lewis, additional

Published
2018
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15. Contemporary Characteristics and Outcomes in Chagasic Heart Failure Compared With Other Nonischemic and Ischemic Cardiomyopathy.

Author

Li Shen, Ramires, Felix, Martinez, Felipe, Bodanese, Luiz Carlos, Echeverría, Luis Eduardo, Gómez, Efraín A., Abraham, William T., Dickstein, Kenneth, Køber, Lars, Packer, Milton, Rouleau, Jean L., Solomon, Scott D., Swedberg, Karl, Zile, Michael R., Jhund, Pardeep S., Gimpelewicz, Claudio R., and McMurray, John J. V.

Abstract

BACKGROUND: Chagas' disease is an important cause of cardiomyopathy in Latin America. We aimed to compare clinical characteristics and outcomes in patients with heart failure (HF) with reduced ejection fraction caused by Chagas' disease, with other etiologies, in the era of modern HF therapies. METHODS AND RESULTS: This study included 2552 Latin American patients randomized in the PARADIGM-HF (Prospective Comparison of ARNI With ACEI to Determine Impact on Global Mortality and Morbidity in Heart Failure) and ATMOSPHERE (Aliskiren Trial to Minimize Outcomes in Patients With Heart Failure) trials. The investigator-reported etiology was categorized as Chagasic, other nonischemic, or ischemic cardiomyopathy. The outcomes of interest included the composite of cardiovascular death or HF hospitalization and its components and death from any cause. Unadjusted and adjusted Cox proportional hazards models were performed to compare outcomes by pathogenesis. There were 195 patients with Chagasic HF with reduced ejection fraction, 1300 with other nonischemic cardiomyopathy, and 1057 with ischemic cardiomyopathy. Compared with other etiologies, Chagasic patients were more often female, younger, and had lower prevalence of hypertension, diabetes mellitus, and renal impairment (but had higher prevalence of stroke and pacemaker implantation) and had worse health-related quality of life. The rates of the composite outcome were 17.2, 12.5, and 11.4 per 100 person-years for Chagasic, other nonischemic, and ischemic patients, respectively--adjusted hazard ratio for Chagasic versus other nonischemic: 1.49 (95% confidence interval, 1.15-1.94; P=0.003) and Chagasic versus ischemic: 1.55 (1.18-2.04; P=0.002). The rates of allcause mortality were also higher. CONCLUSIONS: Despite younger age, less comorbidity, and comprehensive use of conventional HF therapies, patients with Chagasic HF with reduced ejection fraction continue to have worse quality of life and higher hospitalization and mortality rates compared with other etiologies. [ABSTRACT FROM AUTHOR]

Published
2017
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17. Percutaneous Ventricular Restoration Using the Parachute Device in Patients With Ischemic Heart Failure

Author

Costa, Marco A., primary, Mazzaferri, Ernest L., additional, Sievert, Horst, additional, Abraham, William T., additional, Gradinac, Sinisa, additional, Sagic, Dragan, additional, Otasevic, Petar, additional, Hasan, Ayesha K., additional, Goff, Thomas L., additional, Wunderlich, Nina, additional, DePuy, Venita, additional, and Smart, Frank, additional

Published
2014
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19. Effects of Exercise on Left Ventricular Systolic and Diastolic Properties in Patients With Heart Failure and a Preserved Ejection Fraction Versus Heart Failure and a Reduced Ejection Fraction

Author

Zile, Michael R., primary, Kjellstrom, Barbro, additional, Bennett, Tom, additional, Cho, Yong, additional, Baicu, Catalin F., additional, Aaron, Mark F., additional, Abraham, William T., additional, Bourge, Robert C., additional, and Kueffer, Fred J., additional

Published
2013
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21. An α 2C -Adrenergic Receptor Polymorphism Alters the Norepinephrine-Lowering Effects and Therapeutic Response of the β-Blocker Bucindolol in Chronic Heart Failure

Author

Bristow, Michael R., primary, Murphy, Guinevere A., additional, Krause-Steinrauf, Heidi, additional, Anderson, Jeffrey L., additional, Carlquist, John F., additional, Thaneemit-Chen, Surai, additional, Krishnan, Vaishali, additional, Abraham, William T., additional, Lowes, Brian D., additional, Port, J. David, additional, Davis, Gordon W., additional, Lazzeroni, Laura C., additional, Robertson, Alastair D., additional, Lavori, Phillip W., additional, and Liggett, Stephen B., additional

Published
2010
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23. An α2C-Adrenergic Receptor Polymorphism Alters the Norepinephrine-Lowering Effects and Therapeutic Response of the β-Blocker Bucindolol in Chronic Heart Failure.

Author

Bristow, Michael R., Murphy, Guinevere A., Krause-Steinrauf, Heidi, Anderson, Jeffrey L., Cariquist, John F., Thaneemit-Chen, Surai, Krishnan, Vaishali, Abraham, William T., Lowes, Brian D., Port, J. David, Davis, Gordon W., Lazzeroni, Laura C., Robertson, Alastair D., Lavori, Phillip W., and Stephen B. Liggett

Subjects
HEART failure, ALPHA adrenoceptors, BETA adrenoceptors, ADRENERGIC beta blockers, SYMPATHOLYTIC agents, GENETIC polymorphisms, GENETICS
Abstract

The article focuses on a study which investigated whether alpha-2C-adrenergic receptor (AR) polymorphisms affect sympatholytic effects of bucindolol in patients with chronic heart failure. Outcomes of chronic heart failure were determined by adrenergic activation. The study concluded that alpha-2Creceptor genotype influenced the Beta-Blocker Evaluation of Survival Trial AR polymorphism substudy, the norepinephrine lowering and clinical therapeutic responses to bucindolol.

Published
2010
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24. An 2C-Adrenergic Receptor Polymorphism Alters the Norepinephrine-Lowering Effects and Therapeutic Response of the -Blocker Bucindolol in Chronic Heart Failure

Author

Bristow, Michael R., Murphy, Guinevere A., Krause-Steinrauf, Heidi, Anderson, Jeffrey L., Carlquist, John F., Thaneemit-Chen, Surai, Krishnan, Vaishali, Abraham, William T., Lowes, Brian D., Port, J David, Davis, Gordon W., Lazzeroni, Laura C., Robertson, Alastair D., Lavori, Phillip W., and Liggett, Stephen B.

Abstract

Adrenergic activation is an important determinant of outcomes in chronic heart failure. Adrenergic activity is regulated in part by prejunctional 2C-adrenergic receptors (ARs), which exhibit genetic variation in humans. Bucindolol is a novel -AR blocking agent that also lowers systemic norepinephrine and thus is also a sympatholytic agent. This study investigated whether 2C-AR polymorphisms affect sympatholytic effects of bucindolol in patients with heart failure.

Published
2010
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