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3 results on '"Lattanzi, G."'

2. Constitutive heterochromatin: a surprising variety of expressed sequences

Author

Ruggiero Caizzi, Ennio Giordano, Patrizio Dimitri, Maria Carmela Accardo, Giovanna Lattanzi, Giuseppe Biamonti, Dimitri, P, Caizzi, R, Giordano, Ennio, Carmela Accardo, M, Lattanzi, G, and Biamonti, G.

Subjects
Genetics, Genome evolution, Euchromatin, Heterochromatin, fungi, Chromosome Mapping, Gene Expression, Genomics, Biology, Genome, Drosophila melanogaster, Eukaryotic chromosome fine structure, Constitutive heterochromatin, Animals, Humans, Heterochromatin protein 1, Drosophila, Genetics (clinical), Pericentric heterochromatin, In Situ Hybridization, Fluorescence
Abstract

The organization of chromosomes into euchromatin and heterochromatin is amongst the most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is a basic yet still poorly understood component of eukaryotic chromosomes, and its molecular characterization by means of standard genomic approaches is intrinsically difficult. Although recent evidence indicates that the presence of transcribed genes in constitutive heterochromatin is a conserved trait that accompanies the evolution of eukaryotic genomes, the term heterochromatin is still considered by many as synonymous of gene silencing. In this paper, we comprehensively review data that provide a clearer picture of transcribed sequences within constitutive heterochromatin, with a special emphasis on Drosophila and humans.

Published
2008

3. Constitutive heterochromatin: a surprising variety of expressed sequences.

Author

Dimitri P, Caizzi R, Giordano E, Carmela Accardo M, Lattanzi G, and Biamonti G

Subjects
Animals, Chromosome Mapping, Drosophila melanogaster genetics, Humans, In Situ Hybridization, Fluorescence, Gene Expression, Heterochromatin genetics
Abstract

The organization of chromosomes into euchromatin and heterochromatin is amongst the most important and enigmatic aspects of genome evolution. Constitutive heterochromatin is a basic yet still poorly understood component of eukaryotic chromosomes, and its molecular characterization by means of standard genomic approaches is intrinsically difficult. Although recent evidence indicates that the presence of transcribed genes in constitutive heterochromatin is a conserved trait that accompanies the evolution of eukaryotic genomes, the term heterochromatin is still considered by many as synonymous of gene silencing. In this paper, we comprehensively review data that provide a clearer picture of transcribed sequences within constitutive heterochromatin, with a special emphasis on Drosophila and humans.

Published
2009
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