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Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To investigate the effect of the strong bone and muscle form ula on bone mineral density ( BMD ) and IL-17 level in ovariectomized ra ts. Methods Thirty SPF grade 6-month-old female SD rats were divided into Sham group ( 11 = 9) and model group ( n = 21) according to random number table. After 12 weeks, 3 rats were respectively se lected from the Sham group and OVX group for lumbar vertebrae BMD test to verify the success of modeling. Rats in the model group were divided into OVX group ( n = 6), ZGQJ group ( n = 6 ), and Alen group ( n = 6 ). Rats in ZGQJ group received the strong bone and muscle formu la. Rats in Alen group received alendronate sodium. After 12 weeks of the treatment, the rats were sacrificed. BMD of the lumbar vertebrae was detected with DEXA. The microstructure of the tibia was detected with micro-CT. The structure of the femur and spleen was observed with HE staining. Serum level of IL-17 was detected with ELISA. The level of IL-17 in the tibia was detected with immunofluorescent staining. The level of IL-17 in the spleen was detected with immunohistochemistry. Results Compared to that in OVX group, the lumbar vertebrae BMD in ZGQJ and Alen group increased significantly ( P

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective To systematically review the efficacy of traditional Chinese medicine (TCM) decoction or Chinese patent medicine for primary osteoporosis (POP) in Yang deficiency of the spleen and kidney, and to provide evidence for clinical decisionmaking. Methods Databases including China National Knowledge Infrastructure (CNKI), Chinese Science and Technology Periodical Database (VIP), Wanfang data, China Biology Medicine disc (CBM), Pub Med, and Em base were searched from the establishment to 1 March 2022. Randomized controlled trials with TCM treatment for POP in type of Yang deficiency of the spleen and kidney were identified. The quality assessment was conducted by using the Cochrane risk of bias tool. Meta-analysis was performed using RevMan version 5. 3. Results Seventeen studies were included. Meta-analysis showed that in comparison with non-TCM treatment, TCM invigorating spleen and kidney showed a favorable effect in the total effective rate compared with Western medicine based on the change of bone mineral density (OR= 3. 22, 95% Cl 2. 07, 5. 00, P<0. 000 01) and the total effective rate of TCM assessed by TCM syndrome score (OR= 6. 26, 95% Cl 3. 12, 12. 58, P<0. 000 01). Compared with non-TCM, TCM showed a superior impact in improvement of lumbar bone mineral density (SMD = 0. 49, 95% CI 0. 03, 0. 95, P = 0. 03<0. 05), reduction of TCM syndrome scores (SMD = -1. 01, 95% CJ- I. 29, - 0. 73, P < 0. 000 01) and visual analogue scale (VAS, SMD = -1. 58, 95% Cl-2. 42, -0. 74, P = 0. 000 2<0. 05). There were no significant side effect to the patients. Conclusion In the treatment of POP with Yang deficiency of the spleen and kidney, TCM treatment is more effective in improving the total clinical effective rate, lumbar bone mineral density, reducing TCM syndrome score, and VAS than conventional Wes tern medicine treatment. Additionally, TCM has the advantage of high safety. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Osteoporosis is the property of Chinese Journal of Osteoporosis and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)