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A convenient synthesis of intermediate 4,5-diamino-3-aryl-1-phenylpyrazoles 4a–4c was reported. The different cyclization reactions were carried out with chalcone, 2-mercaptoacetic acid and p-anisialdehyde, ethyl chloroformate, glyoxal and thiourea to afford different N and S containing heterocycles. The reaction conditions were compared by conventional heating and microwave irradiation. The structures of the cyclization products were determined by analytical and spectroscopic data. All the synthesized compounds were screened for antibacterial activities in vitro.

3-Amino-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (1) was used as starting material for the synthesis of a number of azo compounds 3a–3c and azomethine derivative 4. The deblocking of 3a–3c and 4 gave rise to 5a–5c and 6 in which a free amino was revealed. The diazonium salts of 5a–5c and 6 were coupled with several phenols to produce a number of bis azo compounds 7a–7c and 8a–8c with azomethine in position 4 and azoic group in position 3. The prepared dyes were structurally confirmed by elemental analysis, spectral methods and applied to different fibers (wool, polyester and blend of wool/polyester) as disperse dyes and their fastness properties were measured.