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Objective To analyze the development status and research trend of premature ejaculation treatment. Methods By systematically searching the Web of Science (WoS) core collection database, the related literatures to premature ejaculation treatment were obtained from January 1, 2000 to December 31, 2020. The distribution characteristics, research hotspots, and research frontiers of global research literatures on premature ejaculation treatment were visually analyzed using CiteSpace software. Results A total of 2 433 articles were included, and 10 keyword clustering labels were formed. Research hotspots mainly focused on the epidemiological characteristics and treatment of premature ejaculation, and research trends on systematic evaluation of diseases and nursing care. Conclusion The treatment of premature ejaculation has received increasing attention in the last two decades. In the future, we will strengthen international exchanges to promote research on premature ejaculation treatment in China relying on the cultural background of the Chinese medical field. [ABSTRACT FROM AUTHOR]

Objective To explore medication rules of traditional Chinese medicine in the treatment of teratozoospermia based on clinical literature data mining for providing guidance methods for teratozoospermia treatment. Methods Clinical literatures on teratozoospermia treatment with traditional Chinese medicine from database establishment to December 31,2022 were retrieved and collected from the database of CNKI, Wanfang and VIP. SPSS and Excel were used for data mining to summarize the clinical medication rules of teratozoospermia. Results A total of 101 related literatures were initially retrieved, and 57 clinical literatures were ultimately obtained, including 64 prescriptions containing 145 kinds of traditional Chinese medicine. Eight syndrome elements were extracted, mainly including essence deficiency, blood stasis, damp-heat and yin deficiency. The disease mainly located in kidney, spleen and liver. Cuscuta chinensis and Lycium barbarum were the most common clinical drugs, and the main drugs were tonic drugs. The property of the drug was warm and mild, the taste of the drug was mainly sweet, and the meridian tropism was mainly in the kidney, liver and spleen. Association rule analysis showed that there were 8 pairs of combinations with high correlation strength, and the results of hierarchical cluster analysis revealed 3 categories. The network visualization of association rules indicated that the core drugs included 16 kinds such as dodder, wolfberry fruit, cornus officinalis, prepared rehmannia root, etc., and the compatibility correlation between drugs was high. Conclusion The basic pathogenesis of teratozoospermia is essence deficiency and kidney deficiency, damp-heat descending and blood stasis blocking collaterals. The main treatment is to tonify deficiency, clear heat, remove dampness and activate blood circulation. [ABSTRACT FROM AUTHOR]