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The BF3OEt2catalyzed one-pot 1,3-dipolar cycloaddition reaction of benzylamines, isatins and dimethyl acetylenedicarboxylate in dry methylene dichloride afforded the functionalized spiro[indoline-3,2′-pyrroles] in moderate to good yields and with high diastereoselectivity.

A series of difunctionalized copillar[5]arene Schiff bases from the condensation of salicylaldehyde and its 5-chloro, 5-bromo, 3,5-di(t-butyl) substituted derivatives with corresponding di-amino-functionalized pillar[5]arenes were successfully prepared. The single crystal structures and coordination properties to some transition metal ions were investigated.

The three-component reaction of triphenylphosphine, dialkyl but-2-ynedioate and arylidene pivaloylacetonitrile in dry methylene dichloride at room temperature resulted in unexpected densely substituted 1-(triphenyl-λ5-phosphanylidene)ethyl)-2,3-dihydrofurans in satisfactory yields with high diastereoselectivity.

The series of salen-bridged bis-pillar[1]arenes were conveniently prepared by condensation reaction of 5,5′-methylenebis(2-hydroxybenzaldehyde) or 5,5′-(propane-2,2-diyl)bis(2-hydroxybenzaldehyde) with mono-amido-functionalized pillar[5]arenes. The 1H NMR and 2D-NOESY spectra as well as single crystal structure clearly indicated that the salen-bridged bis-pillar[5]arenes with longer alkylene linker (m = 0, 1, 3) formed the fascinating bis-[1]rotaxanes, while those with short hydrazine and ethylenediamino linker predominately existed in free form.

The base promoted four-component reaction of hydrated hydrazine, dimethyl acetylenedicarboxylate, isatines and malononitrile (ethyl cycanoacetate) in ethanol afforded polysubstituted spiro[indoline-3,4′-pyrano[2,3-c]pyrazoles] and spiro[acenaphthyl-3,4′-pyrano[2,3-c]pyrazoles].

Three-component reaction of β-naphthol, isatins and cyclic amines, such as piperidine or morpholine, in methylene dichloride without any other catalyst afforded new type of Betti bases in good yields.