1. Development of anaplastic ependymoma in Rasmussen’s encephalitis: review of the literature and case report
- Author
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Raj Kumar, Sunil Pradhan, Lily Pal, Jaypal Sangala Reddy, and AA Wani
- Subjects
Male ,Ependymoma ,Rasmussen's encephalitis ,Pediatrics ,medicine.medical_specialty ,Malignant Ependymoma ,Anaplastic Ependymoma ,X ray computed ,medicine ,Humans ,Child ,Cerebral Cortex ,Brain Neoplasms ,business.industry ,Infant ,General Medicine ,medicine.disease ,Child, Preschool ,Pediatrics, Perinatology and Child Health ,Encephalitis ,Neurology (clinical) ,Neurosurgery ,Atrophy ,Tomography, X-Ray Computed ,business ,Intractable seizures - Abstract
Rasmussen's encephalitis (RE) is a form of chronic encephalitis presenting with intractable seizures and progressive neurological deficits in children. The occurrence of anaplastic ependymoma in a diagnosed case of RE has not been reported in the literature.We report an eight and a half year-old boy, a diagnosed case of RE, suffering from intractable right-sided focal seizures, who developed features of raised intracranial pressure during follow-up. Repeat imaging revealed left fronto-temporoparietal mass for which near-total decompression was done. Histopathology of the mass revealed anaplastic ependymoma.The etiology of such a co-existence or development of malignancy in a pre-existing RE is yet to be completely understood. Both these entities could have a common etiology of viral- or autoimmune-mediated process, but no definite conclusion can be drawn with all the literature available at the moment.
- Published
- 2005
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