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Your search keyword '"MISHIMA, Michiaki"' showing total 29 results
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29 results on '"MISHIMA, Michiaki"'

26. An automated method to assess the distribution of low attenuation areas on chest CT scans in chronic pulmonary emphysema patients

Author

Sakai, Naoki, Mishima, Michiaki, Nishimura, Koichi, Itoh, Harumi, and Kuno, Kenshi

Subjects
Emphysema, Pulmonary -- Diagnosis, Lung diseases, Obstructive -- Diagnosis, CT imaging -- Usage, Health, Diagnosis, Usage
Abstract

We developed an automated method to recognize the lung in a computed tomographic (CT) image. With computer-assisted analysis, we were able to describe the continuous low attenuation (less than --960 [...]

Published
1994

28. Environmental Risk Factors for Pulmonary Mycobacterium avium-mtracellulare Complex Disease.

Author

Maekawa, Koichi, Ito, Yutaka, Hirai, Toyohiro, Kubo, Takeshi, Imai, Seiichiro, Tatsumi, Shuji, Fujita, Kohei, Takakura, Shunji, Niimi, Akio, Iinuma, Yoshitsugu, Ichiyama, Satoshi, Togashi, Kaori, and Mishima, Michiaki

Subjects
MYCOBACTERIUM avium, ENVIRONMENTAL exposure, IMMUNE system, LUNG diseases, SOILS, PATIENTS, HEALTH
Abstract

The article presents a study which aims to examine the environmental risk factors in immunocompetent patients with pulmonary Mycobacterium avium-intracellulare complex (MAC) disease. Environmental exposures included water exposure from bathing, pet exposure and soil exposure from farming. The study reveals that patients having pulmonary MAC disease had more soil exposure than noninfected control patients, suggesting that soil exposure is probably risk factor for developing pulmonary MAC disease.

Published
2011
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29. A Comparison of the Effects Salbutamol and Ipratropium Bromide on Exercise Endurance in Patients With COPD.

Author

Oga, Toru, Nishimura, Koichi, Tsukino, Mitsuhiro, Sato, Susumu, Hajiro, Takashi, and Mishima, Michiaki

Subjects
BRONCHODILATOR agents, OBSTRUCTIVE lung disease treatment, DRUG therapy
Abstract

Study objective: Inhaled bronchodilators are the first-line pharmacotherapy against COPD. The purpose of the present study was to investigate the effects of β[sub 2]-agonists and anticholinergic agents on the exercise capacity of patients with COPD. Methods: A total of 67 stable patients with COPD were recruited at the Kyoto University Hospital. After inhaling 400 µg salbutamol, 80 µg ipratropium bromide, or an identical placebo in a randomized, double-blind, crossover fashion, the patients performed cycle endurance tests at a constant workload of 80% of the maximum work rate reached on progressive cycle ergometry, and the endurance time was recorded. Results: Both salbutamol and ipratropium bromide significantly improved the endurance time by 29 s (15%; p < 0.001) and 27 s (14%; p < 0.001), respectively, in comparison with the placebo. However, there was no statistically significant difference between them (p = 0.71). The dyspnea ratios were also similarly reduced by both bronehodilators. The difference in the endurance time between therapy with salbutamol and placebo was significantly, but moderately, related to the difference between therapy with ipratropium bromide and placebo. In addition, there were no relationships, or only weakly significant relationships, between the change in FEV[sub 1] and the change in the endurance time, the highest oxygen uptake, and the highest minute ventilation for both salbutamol and ipratropium bromide. Conclusions: Therapy with both salbutamol and ipratropium bromide improved exercise capacity, as evaluated by the endurance time, and reduced dyspnea similarly in patients with COPD. In addition, the effects of the different bronchodilators on exercise capacity varied within individuals, and a complex mechanism may be responsible for the different effects of these two bronchodilators on exercise capacity vs airflow limitation. These results support the conclusion that boors can be used as first-line drugs for... [ABSTRACT FROM AUTHOR]

Published
2003
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