1. Prevalence and Risk Factors for Osteoporosis in Individuals With COPD
- Author
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W. Darlene Reid, Yi-Wen Chen, Jessica Bon, Andrew H. Ramsook, and Harvey O. Coxson
- Subjects
Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,COPD ,business.industry ,Copd patients ,Quality assessment ,Osteoporosis ,MEDLINE ,CINAHL ,Critical Care and Intensive Care Medicine ,medicine.disease ,respiratory tract diseases ,3. Good health ,03 medical and health sciences ,0302 clinical medicine ,030228 respiratory system ,Data extraction ,Meta-analysis ,Internal medicine ,Medicine ,030212 general & internal medicine ,Cardiology and Cardiovascular Medicine ,business - Abstract
Background Osteoporosis is prevalent in individuals with COPD. Updated evidence is required to complement the previous systematic review on this topic to provide best practice. The aim of this systematic review and meta-analysis was to quantitatively synthesize data from studies with respect to the prevalence and risk factors for osteoporosis among individuals with COPD. Methods EMBASE, CINAHL, MEDLINE, and PubMed databases were searched for articles containing the key words “COPD,” “osteoporosis,” “prevalence,” and “risk factor.” Eligibility screening, data extraction, and quality assessment of the retrieved articles were conducted independently by two reviewers. Meta-analyses were performed to determine osteoporosis prevalence and risk factors in individuals with COPD. Meta-regression analyses were conducted to explore the sources of heterogeneity. Results The pooled global prevalence from 58 studies was 38% (95% CI, 34-43). The presence of COPD increased the likelihood of having osteoporosis (OR, 2.83). Other significant risk factors for osteoporosis in COPD patients were BMI Conclusions Osteoporosis is prevalent in individuals with COPD, and the prevalence seems to be high and similar in many countries. Patients with COPD should be screened for osteoporosis and contributing risk factors.
- Published
- 2019