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12 results on '"CALABRO', Raffaele"'

2. Bosentan therapy in patients with pulmonary hypertension secondary to congenital heart disease (Eisenmenger physiology)

Author

D'Alto, Michele, Sarubbi, Berardo, Vizza, Carmine D., Romeo, Emanuele, Santoro, Giuseppe, Argiento, Paola, Russo, Maria G., and Calabro, Raffaele

Subjects
Pulmonary hypertension -- Drug therapy, Pulmonary hypertension -- Research, Congenital heart disease -- Risk factors, Congenital heart disease -- Drug therapy, Endothelin -- Dosage and administration, Health, Bosentan (Medication) -- Dosage and administration
Abstract

PURPOSE: To evaluate safety, tolerability, clinical and haemodynamic impact of bosentan, an orally administered endothelin-1 antagonist, in patients with pulmonary hypertension due to congenital heart disease (Eisemnenger syndrome). METHODS: Twelve [...]

Published
2005

11. Range in pulmonary artery systolic pressure among highly trained athletes

Author

Robert Naeije, Rodolfo Citro, Paola Argiento, Giovanni Di Salvo, Eduardo Bossone, Antonello D'Andrea, Enrica Golia, Rosangela Cocchia, Raffaella Scarafile, Pio Caso, Raffaele Calabrò, Michele D'Alto, Lucia Riegler, Giuseppe Limongelli, Maria Giovanna Russo, D'Andrea, A, Naeije, R, D'Alto, M, Argiento, P, Golia, E, Cocchia, R, Riegler, L, Scarafile, R, Limongelli, G, Di Salvo, G, Citro, R, Caso, P, Russo, Mg, Calabro, R, Bossone, E, Limongelli, Giuseppe, DI SALVO, Giovanni, Russo, Maria Giovanna, Calabro', Raffaele, and Bossone, E.

Subjects
Pulmonary and Respiratory Medicine, Adult, Male, medicine.medical_specialty, Systole, Pulmonary Artery, Critical Care and Intensive Care Medicine, Reference Values, Internal medicine, medicine.artery, medicine, Ventricular outflow tract, Humans, Pulmonary Wedge Pressure, Ultrasonography, Doppler, Color, Exercise, Retrospective Studies, Ejection fraction, biology, Athletes, business.industry, Stroke volume, biology.organism_classification, medicine.anatomical_structure, Blood pressure, Pulmonary artery, Cardiology, Vascular resistance, Female, Cardiology and Cardiovascular Medicine, business, Follow-Up Studies
Abstract

BACKGROUND: Although the physiologic range of pulmonary artery systolic pressure (PASP) has been reported, data on how it is manifested in athletes are limited. The aim of the present study was to explore the full spectrum of PASP and the long-term training impact in a large population of highly trained athletes. METHODS: Six hundred fifteen consecutive athletes (370 endurance-trained athletes [ATEs] vs 245 strength-trained athletes [ATSs]; 28.4 ± 10.1 years old) and 230 healthy control subjects (27.5 ± 11.3 years old) underwent transthoracic echocardiography. PASP was estimated by measuring maximal tricuspid regurgitant jet velocity (TRV) with the modified Bernoulli equation. The ratio of TRV to right ventricular outflow tract time-velocity integral (TRV/RVOTTVI) was obtained as a correlate of pulmonary vascular resistance (PVR). RESULTS: Left ventricular (LV) mass index and ejection fraction did not differ significantly between the two groups of athletes. Conversely, ATSs showed an increased sum of wall thickness and relative wall thickness, whereas LV end-diastolic diameter, LV stroke volume, peak TRV, and PASP were significantly higher in ATEs. The ratio between transmitral E wave and tissue Doppler e' wave was not different among the three groups. The ratio TRV/RVOTTVI was ≤ 0.2 (ie, normal PVR) in all subjects. A TRV value > 2.5 m/s was observed in 76 athletes (12.3%). By multivariable analysis, age (P < .01), type and duration of training (P < .01), and LV stroke volume (P < .001) were the only independent predictors of PASP in athletes. CONCLUSIONS: This study delineates the full range of resting TRV and derived PASP in highly trained athletes. The upper physiologic limit of PASP in endurance athletes may reach 40 mm Hg, in line with the greater increase in stroke volume. This should be considered a "physiologic phenomenon" when evaluating athletes for sports eligibility.

Published
2010

12. Morphology of Ductus Arteriosus and of the Pulmonary Arteries in Patients With Pulmonary Atresia and Complex Congenital Heart Disease

Author

Ugo Vairo, Raffaele Calabrò, Bruno Marino, Carlo Marcelletti, Marino, B, Vairo, U, Marcelletti, C, and Calabro', Raffaele

Subjects
Heart Defects, Congenital, Heart Septal Defects, Ventricular, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Adolescent, Transposition of Great Vessels, Critical Care and Intensive Care Medicine, Internal medicine, Ductus arteriosus, medicine.artery, medicine, Humans, In patient, Complex congenital heart disease, Child, Ductus Arteriosus, Patent, Lung, business.industry, Infant, Newborn, Infant, Arteries, medicine.disease, Aorticopulmonary septum, medicine.anatomical_structure, Child, Preschool, Atresia, Pulmonary artery, Cardiology, Cardiology and Cardiovascular Medicine, Pulmonary atresia, business
Abstract

1990;97;766b-766 Chest B Marino, U Vairo, C Marcelletti and R Calabro atresia and complex congenital heart disease. pulmonary arteries in patients with pulmonary Morphology of ductus arteriosus and of the http://chestjournal.chestpubs.org/content/97/3/766b.citation can be found online on the World Wide Web at: The online version of this article, along with updated information and services ) ISSN:0012-3692 http://chestjournal.chestpubs.org/site/misc/reprints.xhtml ( without the prior written permission of the copyright holder. reserved. No part of this article or PDF may be reproduced or distributed Chest Physicians, 3300 Dundee Road, Northbrook, IL 60062. All rights of been published monthly since 1935. Copyright1990by the American College is the official journal of the American College of Chest Physicians. It has Chest

Published
1990

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