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2. All-transRetinoic Acid Modulates the Balance of Matrix Metalloproteinase-9 and Tissue Inhibitor of Metalloproteinase-1 in Patients With Emphysema*

Author

Mao, Jenny T., Tashkin, Donald P., Belloni, Paula N., Baileyhealy, Irene, Baratelli, Felicita, and Roth, Michael D.

Abstract

The balance between proteases and antiproteases plays an essential role in the pathogenesis of emphysema. This study was designed to evaluate the impact of all-transretinoic acid (ATRA) on the balance of matrix metalloproteinase-9 (MMP-9) and tissue inhibitor of metalloproteinase-1 (TIMP-1) in patients with emphysema.

Published
2003
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