1. Cyclopentyl Methyl Ether: An Elective Ecofriendly Ethereal Solvent in Classical and Modern Organic Chemistry
- Author
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Ugo Azzena, Massimo Carraro, Luisa Pisano, Vittorio Pace, Serena Monticelli, and Roberta Bartolotta
- Subjects
Green chemistry ,organometallic chemistry ,General Chemical Engineering ,Cyclopentyl methyl ether ,Reviews ,02 engineering and technology ,Review ,solvent effects ,010402 general chemistry ,01 natural sciences ,Catalysis ,chemistry.chemical_compound ,Environmental Chemistry ,Organic chemistry ,General Materials Science ,Organometallic chemistry ,green chemistry ,021001 nanoscience & nanotechnology ,Environmentally friendly ,0104 chemical sciences ,Solvent ,General Energy ,ethers ,chemistry ,synthetic methods ,Chemical stability ,Solvent effects ,0210 nano-technology - Abstract
Solvents represent one of the major contributions to the environmental impact of fine‐chemical synthesis. As a result, the use of environmentally friendly solvents in widely employed reactions is a challenge of vast real interest in contemporary organic chemistry. Within this Review, a great variety of examples showing how cyclopentyl methyl ether has been established as particularly useful for this purpose are reported. Indeed, its low toxicity, high boiling point, low melting point, hydrophobicity, chemical stability towards a wide range of conditions, exceptional stability towards the abstraction of hydrogen atoms, relatively low latent heat of vaporization, and the ease with which it can be recovered and recycled enable its successful employment as a solvent in a wide range of synthetic applications, including organometallic chemistry, catalysis, biphasic reactions, oxidations, and radical reactions.
- Published
- 2018