1. Intramolecular Photogeneration of a Tyrosine Radical in a Designed Protein
- Author
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Christian Herrero, Alison G. Tebo, Vincent L. Pecoraro, Ally Aukauloo, Annamaria Quaranta, Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Photocatalyse et Biohydrogène (LPB), Département Biochimie, Biophysique et Biologie Structurale (B3S), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Institut de Biologie Intégrative de la Cellule (I2BC), and Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)
- Subjects
photochemistry ,010405 organic chemistry ,Chemistry ,Charge separation ,Radical ,Tyrosine radical ,[SDV]Life Sciences [q-bio] ,Organic Chemistry ,Protein design ,010402 general chemistry ,Photochemistry ,radicals ,01 natural sciences ,Article ,0104 chemical sciences ,Analytical Chemistry ,Electron transfer ,Intramolecular force ,Tyrosine ,Physical and Theoretical Chemistry ,protein design - Abstract
Long-distance biological electron transfer occurs through a hopping mechanism and often involves tyrosine as a high potential intermediate, for example in the early charge separation steps during photosynthesis. Protein design allows for the development of minimal systems to study the underlying principles of complex systems. Herein, we report the development of the first ruthenium-linked designed protein for the photogeneration of a tyrosine radical by intramolecular electron transfer.
- Published
- 2017
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